Search results for "Mali"
showing 10 items of 3900 documents
LGTBIQfobia audiovisual: La ocultación de colectivos sexualmente diversos en Disney
2021
La LGTBIQfobia supone una barrera para la normalización de colectivos sexualmente diversos. Productos como los audiovisuales Disney dificultan esta tarea ya que la compañía tiende a ocultarlas. De esta manera se frena el desarrollo de una ciudadanía más tolerante y respetuosa con la diferencia desde las primeras edades. En la educación hay una preocupación latente por erradicar el bullying LGTBIQfóbico. Por ello, a través de un posicionamiento queer y de una metodología mixta se analiza la colección “Los clásicos” Disney para manifestar los ataques hacia dicho colectivo y concienciar a quienes la utilizan como recurso en sus aulas con los grupos de menores. También para visibilizar los ejem…
De l’avoir lieu à l’être-lieu : parcours dans l’œuvre de Dorothy Cross
2019
Les installations et performances de Dorothy Cross, artiste contemporaine irlandaise, reposent sur un profond respect de la nature et visent à remettre en cause, de manière poétique, l’anthropocentrisme des sociétés occidentales. En mettant en scène le surgissement inattendu d’une bestialité archaïque symbolisée par le requin, la méduse ou les serpents, animaux sauvages mais culturellement marqués, et en s’immergeant dans des milieux et biotopes sauvages, l’artiste opère des renversements spatiaux : l’espace culturel devient un espace ensauvagé. Les procédés d’inscription, d’incrustation ou de projection de motifs évoquant une nature non domestiquée opèrent une symbiose entre l’homme et l’é…
La utilización de la historia de las ciencias en la enseñanza de la física y la química
1996
Most recently we have assisted to a considerable increase of investigations on cons tructivi Stic approaches to Science teaching, but among all these works we rarely found detailed proposals for including the History and Philosophy of Science. In this paper we consider how to initiate this trend and which should be the aims in order to get a better Science teaching. We consider basically which the pupils’ perceptions of Science in a High School level are in order to show how we can modify them by means of introducing the History of Science under a new perspective.
Autosomal recessive severe dwarfism in a Sicilian girl: a new form of osteodysplastic primordial dwarfism?
1996
A new type of osteodysplastic primordial dwarfism is delineated in a 5- year-old female child with severe growth retardation of prenatal onset, gross skeletal changes, a non-Seckel facial phenotype, and presumed autosomal recessive inheritance.
Data from: Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish
2017
Crude oil spills are a worldwide ocean conservation threat. Fish are particularly vulnerable to the oiling of spawning habitats, and crude oil causes severe abnormalities in embryos and larvae. However, the underlying mechanisms for these developmental defects are not well understood. Here, we explore the transcriptional basis for four discrete crude oil injury phenotypes in the early life stages of the commercially important Atlantic haddock (Melanogrammus aeglefinus). These include defects in (1) cardiac form and function, (2) craniofacial development, (3) ionoregulation and fluid balance, and (4) cholesterol synthesis and homeostasis. Our findings suggest a key role for intracellular cal…
Data from: Negative frequency-dependent selection of sexually antagonistic alleles in Myodes glareolus
2011
Sexually antagonistic genetic variation, where optimal values of traits are sex-dependent, is known to slow the loss of genetic variance associated with directional selection on fitness-related traits. However, sexual antagonism alone is not sufficient to maintain variation indefinitely. Selection of rare forms within the sexes can help to conserve genotypic diversity. We combined theoretical models and a field experiment with Myodes glareolus to show that negative frequency-dependent selection on male dominance maintains variation in sexually antagonistic alleles. In our experiment, high-dominance male bank voles were found to have low-fecundity sisters, and vice versa. These results show …
Data from: The role of morbidly obesity in the promotion of metabolic disruptions and non-alcoholic steatohepatitis by Helicobacter Pylori
2017
Helicobacter pylori (HP) infection has been associated to an increased rate of type 2 diabetes (T2D) and liver disease through its effect on insulin resistance and systemic inflammation. However, results are inconstant and no studies exist in morbidly obese patients, in which both insulin resistance and inflammation coexist. Material and Methods: Cross-sectional study to evaluate the relationship between HP infection and alterations in carbohydrate metabolism, lipid profile, inflammation markers, and liver disease in patients awaiting for bariatric surgery. HP infection was histologically assessed in gastric antrum biopsy from 416 subjects. Liver biopsy was also available in 93 subjects. Re…
Evaluation of MRI and cannabinoid type 1 receptor PET templates constructed using DARTEL for spatial normalization of rat brains
2015
Purpose: Image registration is one prerequisite for the analysis of brain regions in magnetic-resonance-imaging (MRI) or positron-emission-tomography (PET) studies. Diffeomorphic anatomical registration through exponentiated Lie algebra (DARTEL) is a nonlinear, diffeomorphic algorithm for image registration and construction of image templates. The goal of this small animal study was (1) the evaluation of a MRI and calculation of several cannabinoid type 1 (CB1) receptor PET templates constructed using DARTEL and (2) the analysis of the image registration accuracy of MR and PET images to their DARTEL templates with reference to analytical and iterative PET reconstruction algorithms. Methods:…
The role of the Thomsen-Friedenreich antigen as a tumor-associated molecule.
1990
The Thomsen-Friedenreich antigen (Gal-GalNAc) represents a tumor-associated molecule, which is assumed to be one of the few chemically well-defined antigens with a proven association with malignancy. In order to analyze the role of the carbohydrate structure Gal-GalNAc for gastrointestinal tumors, we immunized Balb/c mice with MCF-7 breast tumor cells together with synthetic Gal-GalNAc linked to a BSA carrier. One monoclonal antibody (82-A6) was established which recognizes the Thomsen-Friedenreich antigen according to the biochemical and serological analysis presented here. In contrast to the studies performed in the past, immunohistochemical results using this antibody 82-A6 did not exhib…
Potential drug-drug interaction between duloxetine and acenocoumarol in a patient with Alzheimer's disease
2007
Abstract Background : Recent evidence suggests that duloxetine may increase the effect of warfarin, thereby increasing the possibility of bleeding. However, a MEDLINE search for articles published between 1980 and May 2007 (terms: duloxetine , anticoagulants , acenocoumarol , and interaction ; no language restriction) did not yield any reports of an interaction between concomitant use of duloxetine and acenocoumarol. Objective : The aim of this study was to describe a potential drug-drug interaction between duloxetine and acenocoumarol in a patient with Alzheimer's disease. The possible mechanism of this potential interaction is examined. Case summary : This report presents the case of a 63…