Search results for "Malo"

showing 10 items of 815 documents

A selective medium for the isolation of malolactic mutants of Leuconostoc oenos

1994

We have developed a selective medium for the isolation of Leuconostoc oenos mutants defective in malolactic fermentation. Forty per cent of colonies isolated directly on selective plates after UV mutagenesis had lost their ability to degrade malate. None of the tested mutants showed any detectable malolactic activity and all lacked a protein band corresponding in size to that of the malolactic enzyme. The availability of such mutants provides a valuable tool both for physiological and genetic research on malolactic fermentation.

MutationbiologyMutantfood and beveragesbiology.organism_classificationmedicine.disease_causeIsolation (microbiology)StreptococcaceaeApplied Microbiology and BiotechnologyMalolactic enzymeMicrobiologyBiochemistrymedicineMalolactic fermentationLeuconostocBacteria
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Redox signaling in acute pancreatitis

2015

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium, cathepsins, pH disorders, autophagy, and cell death, particularly necrosis. This review focuses on the new role of redox signaling in acute pancreatitis. Oxidative stress and redox status are involved in the onset of acute pancreatitis and also in the development of the systemic inflammatory response, being glutathione depletion, xanthine oxidase activation, and thiol oxidation in proteins critical features of the disease in the pancreas. On th…

NecrosisGSH reduced glutathioneSTAT3 signal transducer and activator of transcription 3ERK extracellular signal-regulated kinasesClinical BiochemistryCCK cholecystokininTRAFs TNF receptor associated factorsReview ArticleIκB kinasePharmacologymedicine.disease_causeBiochemistrySHP small heterodimer partnerSTIM1 stromal interaction molecule 1chemistry.chemical_compoundHATs histone acetyltransferasesMedicineASK1GCL glutamate cysteine ligaseTNF-α tumor necrosis factor alphaIKK IκB kinaseNOS nitric oxide synthaseAcute inflammationHIF hypoxia inducible factorlcsh:QH301-705.5NF-κB nuclear factor kappa BDAMPs damage-associated molecular pattern moleculeslcsh:R5-920biologyGSSG oxidized glutathioneNF-kappa BNLRs nucleotide-binding oligomerization domain (NOD) like receptorsTRADD tumor necrosis factor receptor type 1-associated DEATH domain proteinTRPC3 transient receptor potential channel 3VEGF vascular endothelial growth factorGlutathioneTNFR tumor necrosis factor receptorHMGB1 high-mobility group Box 1 proteinIP3R inositol 145-trisphosphate receptor type 3VCAM-1 Vascular Cell adhesion protein 1Acute DiseaseJNK c-Jun N-terminal kinaseAcute pancreatitisTLRs toll-like receptorsmedicine.symptomlcsh:Medicine (General)Oxidation-ReductionAP-1 activator protein-1Signal TransductionmRNA messenger ribonucleic acidHMGB1ASC apoptosis-associated speck-like protein containing a carboxy-terminal CARDRNS reactive nitrogen speciesPTPs protein tyrosine phosphatasesROS reactive oxygen speciesNADH nicotinamide adenine dinucleotidepHe extracellular pHFAEE fatty acid ethyl estersAP acute pancreatitisHumansXanthine oxidaseCBP CREB-binding proteinRyR endoplasmic reticulum membrane ryanodine receptorsMDA malondialdehydeNO nitric oxideXO xanthine oxidaseASK1 apoptosis signal-regulating kinase-1business.industryOrganic ChemistryAutophagyNADPH nicotinamide adenine dinucleotide phosphateHDACs histone deacetylasesmedicine.diseaseCARS compensatory anti-inflammatory response syndromeXDH xanthine dehydrogenaseIL interleukinIκB inhibitor of kappa BAcute pancreatitisETC Electron transport chainPancreatitisMKPs MAPK phosphatasesSAP severe acute pancreatitischemistrylcsh:Biology (General)DTT dithiothreitolOxidative stressNAC N-acetyl cysteineImmunologybiology.proteinCalciumLysosomesReactive Oxygen SpeciesbusinessMAPK mitogen-activated protein kinaseOxidative stressERCP endoscopic retrograde cholangiopancreatographyRedox Biology
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Formation of fumonisin B(1)-glucose reaction product, in vitro cytotoxicity, and lipid peroxidation on kidney cells.

2010

Fumonisin B(1) (FB(1)) content in corn products decreases during the heating process in foods containing reducing sugars, mainly because of the formation of N-(carboxymethyl)fumonisin B(1). In this study, a rapid method has been developed for the determination of both compounds in corn products using a high-speed blender, Ultra-Turrax, for solvent extraction and liquid chromatography-tandem mass spectrometry. The kinetics of FB(1) degradation and the formation of the Maillard adduct were studied in a model system constituted by corn bread spiked with FB(1) and heated at 160, 180, and 200 degrees C for 3, 6, 10, 15, and 20 min. FB(1) decreased from 0.96 to 0.3 mg/kg and N-(carboxymethyl)fumo…

Neutral redFood HandlingKidneyFumonisinsZea maysLipid peroxidationsymbols.namesakechemistry.chemical_compoundfumonisinFumonisinChlorocebus aethiopskidney cellAnimalsIC50Vero CellsFumonisin B1ChromatographyChemistryfood and beveragesGeneral ChemistryCarbohydrateMalondialdehydeMaillard reactionKineticsGlucosesymbolsLipid PeroxidationGeneral Agricultural and Biological SciencesJournal of agricultural and food chemistry
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Reactive oxygen species induced by beauvericin, patulin and zearalenone in CHO-K1 cells

2008

The cytotoxic effects of mycotoxins, induction of reactive oxygen species (ROS) and generation of lipid peroxidation products in CHO-K1 cells were determined as function of increasing time of exposure and concentrations of beauvericin (BEA), patulin (PAT) and zearalenone (ZEA). The end points were evaluated after 24h of exposure, by the tetrazolium salt (MTT) and neutral red (NR) assays. The IC(50) values obtained on the MTT and NR assays ranged from 0.69 to 79.40 microM and 4.40 to 108.76 microM, respectively. To determine the intracellular production of ROS, the intensity of fluorescence emitted from the probe H(2)-DCFDA was measured. The relative intensity of fluorescence from cells incu…

Neutral redThiobarbituric acidCHO CellsToxicologyPatulinLipid peroxidationchemistry.chemical_compoundCricetulusCricetinaeDepsipeptidesMalondialdehydeTBARSAnimalschemistry.chemical_classificationReactive oxygen speciesfood and beveragesGeneral MedicineMycotoxinsMalondialdehydeBeauvericinPatulinchemistryBiochemistryZearalenoneLipid PeroxidationReactive Oxygen SpeciesToxicology in Vitro
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Theory of Neutrinos: A White Paper

2005

During 2004, four divisions of the American Physical Society commissioned a study of neutrino physics to take stock of where the field is at the moment and where it is going in the near and far future. Several working groups looked at various aspects of this vast field. The summary was published as a main report entitled ``The Neutrino Matrix'' accompanied by short 50 page versions of the report of each working group. Theoretical research in this field has been quite extensive and touches many areas and the short 50 page report provided only a brief summary and overview of few of the important points. The theory discussion group felt that it may be of value to the community to publish the e…

Neutrino mass physics; Matter-antimatter asymmetry of the UniverseParticle physicsSupersymmetric Standard ModelPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaElectric-dipole momentsPhysics beyond the Standard ModelFOS: Physical sciencesGeneral Physics and AstronomyTheoretical researchHigh Energy Physics - Phenomenology (hep-ph)White paperSee-saw mechanismneutriniPublicationParticle Physics - PhenomenologyPhysicsLepton-flavor violationDiscussion groupbusiness.industryHigh Energy Physics::PhenomenologyFísicaMatter-antimatter asymmetry of the UniverseDouble beta decaySettore FIS/02 - Fisica Teorica Modelli e Metodi MatematiciEpistemologyElectroweak symmetry-breakingHigh Energy Physics - PhenomenologyLarge extra dimensionsNeutrino mass physicsHeavy Majorana neutrinosHigh Energy Physics::ExperimentRight-handed neutrinoNeutrinoAnomalous magnetic momentWorking groupbusiness
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Peptidases specific for proline-containing peptides and their unusual peptide-dependent regulation in Oenococcus oeni

2009

International audience; Growth of the lactic acid bacterium (LAB) Oenococcus oeni, which is involved in malolactic fermentation during the winemaking process, is stimulated by peptides originating from yeast. In this study, we investigated the impact of peptides on O. oeni growth, peptidase activity and the expression of genes encoding the studied peptidases. Low levels of PepN activity and very high levels of PepI activity were observed in O. oeni, whereas levels of PepX activity were intermediate. The level of biosynthesis of these O. oeni peptidases was shown to depend on peptides present in the culture medium. These results were confirmed by transcriptional analyses of putative pep gene…

NitrogenPeptideElectrophoretic Mobility Shift AssayBiologyApplied Microbiology and Biotechnology[ CHIM ] Chemical Sciences03 medical and health scienceschemistry.chemical_compoundBiosynthesisGene expressionMalolactic fermentation[CHIM]Chemical SciencesPromoter Regions GeneticChromatography High Pressure LiquidOenococcus030304 developmental biologyOenococcus oeniDNA Primerschemistry.chemical_classification0303 health sciences030306 microbiologyReverse Transcriptase Polymerase Chain ReactionGeneral MedicineSequence Analysis DNAbiology.organism_classificationYeastEnzymechemistryBiochemistryGene Expression RegulationFermentationBiotechnologyPeptide Hydrolases
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Effective diffusion coefficient and diffusion-controlled reactions in insulating solids with defects

1995

Abstract The expressions for effective diffusion coefficient are obtained in the mean field approximation for two-phase system for spatial dimensions of 1, 2 and 3. The existence of potential barrier for diffusion on the phase boundary was taken into account via the boundary conditions. Obtained formulae could be applied in the theory of diffusion-controlled reactions and for interpreting the experimental data on defect diffusion in two-phase media.

Nuclear and High Energy PhysicsMolecular diffusionRadiationMaterials scienceCondensed matter physicsAnomalous diffusionCondensed Matter PhysicsFick's laws of diffusionDiffusion layerPhoton transport in biological tissueGrain boundary diffusion coefficientEffective diffusion coefficientGeneral Materials ScienceDiffusion (business)Radiation Effects and Defects in Solids
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The Hunt for New Physics at the Large Hadron Collider

2010

233 páginas.-- AHEP Group: et al..-- El Pdf del artículo es la versión pre-print: arXiv.1001.2693v1.-- Trabajo presentado al "The International Workshop on Beyond the Standard Model Physics and LHC Signatures (BSM-LHC) celebrado en Boston (USA) del 2 al 4 de junio de 2009.

Nuclear and High Energy PhysicsParticle physicsCold dark matterPhysics::Instrumentation and DetectorsPhysics beyond the Standard ModelFOS: Physical sciencesRANDALL-SUNDRUM MODEL01 natural sciencesHigh Energy Physics - Phenomenology (hep-ph)R-PARITY BREAKING0103 physical sciencesHigh Energy PhysicsANOMALOUS MAGNETIC-MOMENT010306 general physicsParticle Physics - PhenomenologyPhysicsEXPLICIT CP VIOLATIONDARK-MATTER DETECTIONLarge Hadron Collider010308 nuclear & particles physicsPhysicsElectroweak interactionHigh Energy Physics::PhenomenologyFísicaRENORMALIZATION-GROUP EQUATIONSHierarchy problemSupersymmetryAtomic and Molecular Physics and OpticsGRAND UNIFIED THEORIESSUPERSYMMETRIC STANDARD MODELHidden sectorExtra dimensionsHigh Energy Physics - PhenomenologyMINIMAL FLAVOR VIOLATION[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]PhenomenologyHigh Energy Physics::ExperimentHIGGS-BOSON PRODUCTION
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Power Corrections to Event Shapes with Mass-Dependent Operators

2013

We introduce an operator depending on the "transverse velocity'' r that describes the effect of hadron masses on the leading 1/Q power correction to event-shape observables. Here, Q is the scale of the hard collision. This work builds on earlier studies of mass effects by Salam and Wicke [J. High Energy Phys. 05 (2001) 061] and of operators by Lee and Sterman [Phys. Rev. D 75, 014022 (2007)]. Despite the fact that different event shapes have different hadron mass dependence, we provide a simple method to identify universality classes of event shapes whose power corrections depend on a common nonperturbative parameter. We also develop an operator basis to show that at a fixed value of Q, the…

Nuclear and High Energy PhysicsParticle physicsExponentiationFOS: Physical sciences01 natural sciencesOperator (computer programming)High Energy Physics - Phenomenology (hep-ph)Factorization0103 physical sciencesRenormalonsResummationFactorization010306 general physicsMathematical physicsPhysicsQuantum chromodynamics010308 nuclear & particles physicsMultiplicative functionObservableUniversality (dynamical systems)HadronizationHigh Energy Physics - PhenomenologyQCD correctionsE&E-annihilationDistributionsResummationJet cross-sectionsQuantum chromodynamics
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Muon Anomaly from Lepton Vacuum Polarization and The Mellin--Barnes Representation

2008

We evaluate, analytically, a specific class of eighth--order and tenth--order QED contributions to the anomalous magnetic moment of the muon. They are generated by Feynman diagrams involving lowest order vacuum polarization insertions of leptons $l=e,\mu$, and $\tau$. The results are given in the form of analytic expansions in terms of the mass ratios $m_e/m_\mu$ and $m_\mu/m_\tau$. We compute as many terms as required by the error induced by the present experimental uncertainty on the lepton masses. We show how the Mellin--Barnes integral representation of Feynman parametric integrals allows for an easy analytic evaluation of as many terms as wanted in these expansions and how its underlyi…

Nuclear and High Energy PhysicsParticle physicsFOS: Physical sciences01 natural sciencesRenormalizationsymbols.namesakeHigh Energy Physics - Phenomenology (hep-ph)Vacuum PolarizationMuon Anomaly0103 physical sciencesFeynman diagramVacuum polarization010306 general physicsMathematical physicsPhysicsMuonMellin-Barnes RepresentationAnomalous magnetic dipole moment010308 nuclear & particles physicsConverse MappingRenormalization groupHigh Energy Physics - PhenomenologyMultidimensional Residues[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]symbolsAnomaly (physics)Lepton
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