Search results for "Mania"
showing 10 items of 710 documents
Constituents of Peperomia vulcanica Baker & C. H. Wright (Piperaceae) with antiparasitic activity
2021
Abstract The investigation of the CH2Cl2-MeOH (1:1) extract of Peperomia vulcanica which showed antileishmanial activity during preliminary screening led to the isolation of two previously unknown compounds named peperolignan (1) and peperotannin (2) along with 13 known compounds. Their structures were determined on the basis of their spectroscopic data. The isolated compounds were assessed in vitro for their antileishmanial and antiplasmodial activities against Leishmania donovani 1S (MHOM/SD/62/1S) promastigotes and the Plasmodium falciparum chloroquine-sensitive 3D7 strain (Pf3D7), respectively. They were also assessed for their cytotoxicity on Raw 264.7 macrophage cells. The mixture of …
La inserción laboral de los inmigrantes rumanos y búlgaros en España
2008
Este artículo analiza la incorporación al mercado de trabajo español de los inmigrantes de nacionalidad búlgara y rumana, dos de los colectivos extranjeros que más han crecido en los últimos años. Tras elaborar un breve estado de la cuestión sobre el tema, se analiza su evolución numérica reciente y su distribución geogràfica a nivel de Comunidades Autónomas, sus características sociodemográficas y laborales a partir de la EPA y, finalmente, su inserción laboral por sector de actividad desde la perspectiva de la complementariedad con la población española ocupada en esos mismos sectores. Las conclusiones se centran en subrayar tanto las semejanzas como las diferencias existentes entre ambos…
Biogeography and diversity of South Atlantic Cretaceous echinoids: implications for circulation patterns
2000
Abstract This survey of echinoid species living on the African and South American margins of the South Atlantic Ocean in Cretaceous times is based on a review of published species and abundant unpublished material. The synthetic approach is used to ascertain how the South Atlantic was colonised by echinoids from the time it first opened in the Early Cretaceous until communications were established with the North Atlantic and Mediterranean–Tethys in the Late Cretaceous. The survey focuses on the biogeographical origin of immigrant species and their relations with Indo-Madagascan, North Atlantic and Mediterranean–Tethyan faunas. Qualitative variations in species diversity are also studied whe…
Shifting urban namescapes: street name politics and toponymic change in a Romanian(ised) city
2019
Abstract Street names express the spatial materialisation of nominative discourses articulated and deployed by the powerful in their politicisation of the urban landscape with self-legitimising ideological values, political symbols and historical narratives. Using an approach grounded upon the theoretical principles of critical toponymies, this paper sets out a longitudinal perspective on the politics of street nomenclature in Hermannstadt/Sibiu (Romania). For this purpose, a dataset comprising the complete historical record of street names in Sibiu between 1829 and 2018 was constructed. The analysis focuses on capturing the ethnopolitics played out at the level of the city's street names t…
L'esercizio dell'azione e il giudizio di prima istanza, tra ordinamento italiano e tedesco. Spunti comparatistici a margine dell'opera di Manfred Mai…
2010
Premettendo alcune considerazioni sulle finalità della ricerca comparatistica, l''Autore mette a confronto alcuni istituti del processo penale italiano e di quello tedesco, facendo particolare riferimento al momento dell''esercizio dell''azione e al giudizio di primo grado. Oltre alle diversità di fondo, vengono evidenziate le principali questioni interpretative e le iniziative di riforma affacciatesi in relazione ai due sistemi, per verificare il rispettivo livello di rispondenza di questi ultimi alle istanze maturate sul piano europeo.
Croce e la modernità tedesca
2017
The book collects the proceedings of the international symposium held with the support of the DFG in 2016 at Villa Vigoni about the relationship between Benedetto Croce and German culture. In particular, the essays deal with the question of the crisis of modernity in German culture through a spectrum of inquiries ranging from Kant to Th. Mann. Il volume costituisce l'edizione italiana dei materiali del seminario internazionale svoltosi con il sostegno della DFG nel 2016 presso Villa Vigoni, avente per argomento il ruolo di Croce in Germania e della cultura tedesca per Croce. In particolare, i singoli contributi affrontano la questione della crisi della modernità nella cultura tedesca in uno…
La Bailía General de València en tiempo de Germania
2021
espanolEl presente trabajo pretende abordar la Bailia General de Valencia durante la revuelta de la Germania. Esta institucion encargada de gobernar el Real Patrimonio hubo de enfrentarse a dificiles situaciones y crear nuevas soluciones a los problemas planteados por los agermanados. Su estudio nos permitira aproximarnos a un acontecimiento que marco la Historia Moderna del reino de Valencia y que todavia hoy suscita interes. EnglishThe present work tries to approach the General Bailiwick of Valencia during the revolt of the Germania. This institution in charge of governing the Royal Heritage had to face difficult situations and create new solutions to the problems posed by the revolted. I…
Sexual Exploitation in the Destination Country
2020
When the vulnerability of Nigerian and Romanian women in human trafficking is concerned, it is not only important to understand the causes that led the victim into a situation of trafficking, but also to understand the factors that maintain the individual in a situation of victimisation. However, this does not mean that these factors are separated according to the different phases of trafficking. On the contrary, it demonstrates that the accumulation of different factors can generate a higher or lower level of vulnerability, as well as the balance of factors affecting the women during the different phases. Therefore, in this chapter I will put forward a general analysis of the different fac…
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis
2018
Abstract: Chemotherapy is currently the only effective approach to treat all forms of leishmaniasis. However, its effectiveness is severely limited due to high toxicity, long treatment length, drug resistance, or inadequate mode of administration. As a consequence, there is a need to identify new molecular scaffolds and targets as potential therapeutics for the treatment of this disease. We report a small series of 1,2‐substituted‐1H‐benzo[d]imidazole derivatives (9ad) showing affinity in the submicromolar range (Ki = 0.150.69 μM) toward Leishmania mexicanaCPB2.8ΔCTE, one of the more promising targets for antileishmanial drug design. The compounds confirmed activity in vitro against intrace…
Can google trends and wikipedia help traditional surveillance? A pilot study on measles
2019
Introduction: Cases of measles in some European countries are increasing. The aim of this study is to find the correlation between Google Trends and Wikipedia searches and the real number of cases notified. Materials and Methods: The data on Internet searches have been obtained from Google Trends and Wikipedia. The reported cases of measles were selected from January 2013 until December 2018 for Google Trends and July 2015 until December 2018 from for Wikipedia. We have selected data from four European Countries: Italy, France, Germany and Romania. The data extracted from Wikipedia and Google Trends have been moved over time (Lag), one month in the future and one month in the past. Cross-co…