Search results for "Mania"
showing 10 items of 710 documents
Le criticità riscontrate nelle procedure: esiti della verifica.
2010
Schede di analisi dei casi studio
2010
La pratica del processo di privatizzazione
2010
L’esigenza di acquisire risorse finanziarie e sollevare lo Stato e gli altri enti territoriali dai costi di gestione dei beni culturali ha determinato l’avvio di un diffuso processo di privatizzazione del patrimonio costruito. Gli immobili, alienati o conferiti in concessione a privati per lunghi periodi, sono adibiti a nuove funzioni, che impongono trasformazioni per l’adeguamento a differenti esigenze. Tali interventi richiedono azioni di indirizzo e di controllo, per le quali la pubblica amministrazione ha la necessità di dotarsi di nuovi strumenti, rivolti sia a garantire la permanenza dei valori espressi dai beni, sia ad orientare le scelte in funzione delle politiche di sviluppo del t…
(S)BILANCIAMENTI TRA DIRITTI SOCIALI E LIBERTÀ ECONOMICHE DELL’UNIONE EUROPEA. Diritto di sciopero e libertà di contrattazione collettiva: analisi a …
Comparative high-resolution chemostratigraphy of the Bonarelli Level from the reference Bottaccione section (Umbria-Marche Apennines) and from an equ…
2006
The Bonarelli Level (BL) from the upper Cenomanian portion of the reference Bottaccione section (central Italy) is characterized by the presence of black shales containing high TOC concentrations (up to 17%) and amounts of CaCO3 near to zero. In the absence of carbonate and, consequently, of relative carbon- and oxygen-isotopic data, the elemental geochemistry revealed to be a very useful tool to obtain information about the palaeoclimatic and palaeoceanographic evolution of the Tethys Ocean during the OAE2. Based on several geochemical proxies (Rb, V, Ni, Cr, Si, Ba), the BL is interpreted as a high-productivity event driven by increasingly warm and humid climatic conditions promoting an a…
In vitro evaluation of leishmanicidal properties of a new family of monodimensional coordination polymers based on diclofenac ligand
2020
Some series of isostructural chains with general formula [M(diclof)(HO)]·(EtOH) have been obtained from reaction between diclofenac ligand (diclof) and first row transition salts (M = Mn (1),Ni (2) and Co (3)). These monodimensional coordination polymers have been characterized and their crystal structures have been solved by X-ray diffraction methods, elucidating isostructural compounds that are chains with water molecules acting as bridge between different metallic centers, while diclofenac ligands are coordinated to the octahedral coordination environment of the same. Magnetic studies of these complexes have revealed the existence of moderate ferromagnetic interactions among manganese, n…
“Click” on PLGA-PEG and hyaluronic acid: Gaining access to anti-leishmanial pentamidine bioconjugates
2017
Pentamidine (Pent), an antiparasitic drug used for the treatment of visceral leishmaniasis, has been modified with terminal azide groups and conjugated to two different polymer backbones (PLGA-PEG [PP] copolymer and hyaluronic acid [HA]) armed with alkyne end-groups. The conjugation has been performed by Copper Catalyzed Azido Alkyne Cycloaddition (CuAAC) using CuSO4 /sodium ascorbate as metal source. The novel PP-Pent and HA-Pent bioconjugates are proposed, respectively, as non-targeted and targeted drug delivery systems against Leishmania infections. Moreover, Pent has been encapsulated into PP nanoparticles by the oil-in-water emulsion method, with the aim to compare the biological activ…
Cinema e politiche del vino
2021
Se è vero che il cinema culinario, con le sue storie, pone il problema dell’alterità e della convivenza fra diversi, facendo interagire in un medesimo contesto personaggi portatori di identità culinarie/ culturali eterodosse (cfr. Mangiapane 2015), i film che mettono al centro delle loro storie il vino battono una strada diversa. Da qualche tempo, con la progressiva saturazione da parte dell’industria culturale di ogni possibile appiglio narrativo riconducibile alla cosiddetta gastromania (cfr. Marrone 2014), infatti, il vino ha acquisito una certa visibilità come soggetto cinematografico autonomo, ispirando film a esso interamente dedicati. È il caso di alcuni titoli emblematici: Sideways …
The burden of mood-disorder/cerebrovascular disease comorbidity: essential neurobiology, psychopharmacology, and physical activity interventions
2017
Cardio-vascular diseases (CVDs) and CVD-related disorders (including cerebrovascular diseases; CBVDs) are a major public health concern as they represent the leading cause of mortality and morbidity in developed countries. Patients with CVDs and CBVDs co-morbid with mood disorders, especially bipolar disorder (BD) and major depressive disorder (MDD), suffer reduced quality-of-life and significant disability adjusted for years of life and mortality. The relationship between CVDs/CBVDs and mood disorders is likely to be bidirectional. Evidence for shared genetic risk of pathways involved in stress reaction, serotonin or dopamine signalling, circadian rhythms, and energy balance was reported i…
EDUCATION – IMPORTANT COMPONENT OF SUSTAINABLE DEVELOPMENT
2018
The present paper tackles certain issues regarding education, the educational system, the institution of education and it aims to provide a critical perspective on the Romanian higher education wellbeing in the contemporary international context. The outcome of the paper is to set forth specific recommendations regarding the improvement of education quality in order to ensure proper conditions for its sustainable development.