Search results for "Map"
showing 10 items of 3484 documents
Towards adaptive localization in wireless sensor networks
2012
It is often useful or even indispensable to know the locations of the nodes in a wireless sensor network (WSN), from both network functionality and applications point of view. A potential yet one of the most challenging method is to utilize received signal strength indicator (RSSI) for distance estimation. Albeit easily adopted, using of RSSI is notorious for imprecise distance estimates which can lead to inaccuracies in location estimates. In this paper, we study RSSI-based localization in WSNs through simulation experiments. We evaluate and compare a hybrid algorithm and its modifications with well-known range-based and range-free localization algorithms. Simulation results indicate that …
Activation of mitogen-activated protein kinase by the bradykinin B2receptor is independent of receptor phosphorylation and phosphorylation-triggered …
1999
Recent evidence suggests that serine/threonine phosphorylation and internalization of beta2-adrenergic receptors play critical roles in signalling to the mitogen-activated protein kinase cascade. To investigate whether this represents a general mechanism employed by G protein-coupled receptors, we studied the requirement of these processes in the activation of mitogen-activated protein kinase by G alpha(q)-coupled bradykinin B2 receptors. Mutant B2 receptors impaired in receptor phosphorylation and internalization are fully capable to activate mitogen-activated protein kinase. Bradykinin-induced long-term effects on mitogenic signalling monitored by measuring the transcriptional activity of…
Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type p…
2008
Here we show the increase of invasion of three breast cancer cell lines (8701-BC, MDA-MB-231 and SKBR3) upon long-term co-incubation with culture medium of normal microvascular endothelial cells (MVEC) and normal breast epithelial cells (HB2). The enhancement of invasion relied on the interaction of microvascular endothelial cell and normal breast epithelial cell CXCL12 (SDF1) chemokine, whose expression by breast cancer cells was very low, with the cognate CXCR4 receptor of malignant cells, which resulted in over-expression of the urokinase-type plasminogen activator receptor (uPAR) on their surfaces. uPAR over-expression, showed by RT-PCR and Western blotting, was paralleled by increased …
The yeast putative transcriptional repressor RGM1 is a proline-rich zinc finger protein.
1991
Abstract I have cloned a yeast gene, RGM1, which encodes a proline-rich zinc, finger protein. rgm1 mutants do not show any obvious phenotype but overexpression of RGM1 gene greatly impairs cell growth. The proline-rich region of RGM1 attached to a heterologous DNA binding domain is able to repress the expression of the target gene. RGM1 shares similar zinc finger motifs with the mammalian Egr (early growth response) proteins as well as proline-rich sequences with a high serine and threonine content, suggesting that RGM1 and Egr proteins could have functional similarities.
Production of biologically active light chain of tetanus toxin inEscherichia coli
1993
AbstractThe activity of the light (L) chain of tetanus toxin, and of mutants constructed by site-directed mutagenesis, was studied by expression and purification of the proteins from E. coli. Wild-type recombinant L chain (pTet87) was active in the inhibition of exocytosis from cultured bovine adrenal chromaffin cells, although at a level 5–15% of that of L chain purified from tetanus toxin. L chain mutants which terminated at Leu-438 (pTet89), or which contained a Cys-to-Ser mutation at residue 439 (pTet88) were equally as active as the full-length recombinant protein. The reduced activity of pTet87 L chain correlated with C-terminal proteolysis of the protein upon purification. A tryptic …
Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution
2004
Fluorescence in situ hybridization mapping of fully integrated human BAC clones to primate chromosomes, combined with precise breakpoint localization by PCR analysis of flow-sorted chromosomes, was used to analyze the evolutionary rearrangements of the human 3q21.3-syntenic region in orangutan, siamang gibbon, and silvered-leaf monkey. Three independent evolutionary breakpoints were localized within a 230-kb segment contained in BACs RP11-93K22 and RP11-77P16. Approximately 200 kb of the human 3q21.3 sequence was not present on the homologous orangutan, siamang, and Old World monkey chromosomes, suggesting a genomic DNA insertion into the breakpoint region in the lineage leading to humans a…
Seismic Characterization by Inversion of HVSR Data to Improve Geological Modelling
2014
SUMMARY An application of HVSR inversion is presented in order to verify the effectiveness of this technique for purposes of geological reconstruction of the subsoil finalized to studies of seismic microzonation of heavily urbanized areas, where few stratigraphic and geophysical constraints are available and most of the information are derived from the geological maps. In such cases the uncertainty of the results is is enhanced by doubts on the nature of the H/V peaks, not always caused by stratigraphic discontinuities, and to the subjective choices done especially in the step of signal preprocessing. The investigated area (Altavilla Milicia, Sicily) includes the town center and the adjacen…
Una aproximación volumétrica a la desagregación espacial de la población combinando cartografía temática y datos LIDAR
2016
[EN] Availability of high resolution population distribution data, independent of the administrative units in which demographic statistics are collected, is a real necessity in many fields: risk evaluation due to earthquakes, flooding or fires, to name just a few, integration between socio-demographic and environmental or geographical information collected in different formats, policy design for the provision public services, such as health, education or public transport, or mobility studies in urban areas or metropolitan regions. Because of this, the literature has explored various methods of population downscaling, collected at communality or census tract level, into smaller areas; typica…
A volumetric approach to spatial population disaggregation using a raster build-up layer, land use/land cover databases (SIOSE) and LIDAR remote sens…
2016
[EN] Availability of high resolution population distribution data, independent of the administrative units in which demographic statistics are collected, is a real necessity in many fields: risk evaluation due to earthquakes, flooding or fires, to name just a few, integration between socio-demographic and environmental or geographical information collected in different formats, policy design for the provision public services, such as health, education or public transport, or mobility studies in urban areas or metropolitan regions. Because of this, the literature has explored various methods of population downscaling, collected at communality or census tract level, into smaller areas; typica…
Finding Factors Influencing Students’ Preferences to Concept Mapping Tasks: Literature Review
2014
Abstract There is a broad set of concept mapping tasks which can be used by teachers for assessing students’ knowledge structures but there are no known works of research studying their adaptation to students’ individual differences and preferences in relation to different tasks. The paper reports first results of activities which aim to offer a solution of the abovementioned problem. It is based on extensive review of theoretical and empirical studies and focuses on: a) identification of advantages and drawbacks of different concept mapping tasks, and b) finding factors which may affect students’ concept mapping ability.