Search results for "Map"

Physico-Geographical Mesoregions of Poland: verification and adjustment of boundaries on the basis of contemporary spatial Data

2018

The programme of identification, cataloguing and evaluation of Polish landscapes, part of the implementation of the European Landscape Convention, has caused an increase in interest in physico-geographical regionalisation over recent years. The commonly accepted regionalisation of Poland developed by J. Kondracki (Kondracki & Richling 1994) is sufficient for work at an overview scale (e.g. 1:500,000), whereas its spatial accuracy is too low to make use of it for the purpose of Polish landscape cataloguing. The aim of this article is to present a more up-to-date and detailed division of Poland into mesoregions, adjusted to the 1:50,000 scale. In comparison with older work, the number of meso…

Introduction to the new Nordic Yearbook and to the thematic section on eighteenth-century philosophy

2009

Evidence of the origin of specific spontaneous head turns during intertrial intervals.

1997

Direction and the frequency of spontaneous head movements during the ITIs following forward and backward paired trials were compared to an acquisition of a conditioned orienting (alpha) response directed to the side of the tone source. The head movements were analyzed from video recordings using classification of head turns to preferred and to nonpreferred directions. The results showed a significant increase in the alpha responses during the forward paired conditioning to the preferred direction and rapid extinction during the subsequent backward conditioning sessions. Spontaneous head movements during the ITIs increased to the same preferred direction as the conditioned alpha responses. T…

Face-work in teacher-in-role: Acting at the interface between artistry and pedagogy

2016

The teacher-in-role (TIR) strategy is used in process drama to strengthen the dramatic experience and promote learning among the participants. In this study, one TIR construct is examined through the lens of Erving Goffman’s concept of facework in order to deepen the understanding of the subtle and vulnerable processes of interaction in process drama. TIR is considered to be an interactive construct in which both artistry and pedagogy are embodied. Face-work is applied in the fictive context of process drama to uncover the interactional potential for learning and creating drama. In addition, the teacher’s reflections on his or her actions as they relate to face-work in process drama are exp…

Città Invisibili of Teatro Potlach: A Journey to Rediscover Our Cultural Heritage

2017

Città Invisibili is a multidisciplinary art project made by the Italian company Teatro Potlach. Compared to the canonical theatrical performances, Città Invisibili, being in its essence a site-specific performance, interacts with the place where it grows. With the project, the Italian group builds next to the existing space of the place (physical space and memory space) other two spaces, the space of the staging and the space of the performer, using different materials, in particular cloths and video projections. Moreover Teatro Potlach conducts a historical, anthropological and social research trying to bring out the latent memory of places. All these interventions bring out from the place…

Co-simulation of bio-inspired multi-agent algorithms

2020

This paper reports on the co-simulation of a team of robots deployed in an exploration task, coordinated by a bio-inspired exploration algorithm. The co-simulation integrates the high-level exploration algorithm with detailed implementations of the robot controllers and kinematic models. Co-simulation results are used to find and correct mismatches between submodels.

Lovastatin causes sensitization of HeLa cells to ionizing radiation‐induced apoptosis by the abrogation of G2 blockage

2003

To investigate the effect of inhibition of Ras/Rho-regulated signalling by 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) on radiation-induced cell killing and apoptosis.Different human cell lines were pretreated or not with lovastatin before exposure to gamma-rays. Afterwards, radiation-induced cell killing, formation and repair of double-strand breaks, activation of radiation-inducible signal mechanisms (i.e. p53, p21, extracellular-signal-related kinase (ERK), NF-kappaB), changes in cell cycle progression and apoptosis were analysed.As shown by a colony formation assay, lovastatin sensitized HeLa cells to gamma-radiation-induced cell killing. The lovastati…

Roflumilast N-oxide reverses corticosteroid resistance in neutrophils from patients with chronic obstructive pulmonary disease

2013

Background Glucocorticoid functions are markedly impaired in patients with chronic obstructive pulmonary disease (COPD). The phosphodiesterase 4 inhibitor roflumilast N-oxide (RNO) is the active metabolite of roflumilast approved as a treatment to reduce the risk of exacerbations in patients with severe COPD. Objective We sought to characterize the differential effects of RNO versus corticosteroids and their potential additive/synergistic effect in neutrophils from patients with COPD, thus providing scientific rationale for the combination of roflumilast with corticosteroids in the clinic. Methods Peripheral blood neutrophils were isolated from patients with COPD (n = 32), smokers (n = 7), …

“Cysteinyl leukotriene-1 receptor activation in a human bronchial epithelial cell line leads to signal transducer and activator of transcription 1-me…

2008

Abstract We studied the effect of leukotriene D(4) (LTD(4)) on a human bronchial epithelial cell line (16HBE) overexpressing the cysteinyl leukotriene (CysLT) (1) receptor (HBECysLT(1)R), looking at the associated signal transduction mechanisms as well as at effects on inflammatory cell adhesion. The results obtained showed that LTD(4) increases the phosphorylation of extracellular signal-regulated protein kinase (ERK) 1/2 and of the signal transducer and activator of transcription 1 (STAT-1) in serine 727 (STAT-1Ser727), resulting in increased eosinophil adhesion to HBECysLT(1)R, associated with enhanced surface expression of intercellular adhesion molecule (ICAM) 1. Pretreatment with a Cy…

Activation and translocation of p38 mitogen-activated protein kinase after stimulation of monocytes with contact sensitizers.

2002

Recently we described the induction of tyrosine phosphorylation by contact sensitizers as an early molecular event during the activation of antigen- presenting cells. In this study, the role of the p38 mitogen-activated protein kinase for the activation of human monocytes after exposure to four structurally unrelated contact sensitizers was analyzed in comparison with the irritant benzalkonium chloride and an inductor of oxidative stress (H 2 O 2 ) using immunofluorescence, Western blotting, and enzyme-linked immunosorbent assay techniques. Bio chemical analysis revealed a translocation of p38 from the cytoplasm to the detergent-resistant cell fraction only upon stimulation with contact sen…