Search results for "Marker"

Diskursa iezīmētāji autora subjektīvās attieksmes paušanai

2018

Bakalaura darba tēma ir „Diskursa iezīmētāji autora subjektīvās attieksmes paušanai”. Izstrādājot darbu izvirzīti uzdevumi – apskatīt dažādu autoru rakstus par attiecīgi darbam nepieciešamajām teorijas tēmām; izstrādāt darba teorētisko pamatu, balstoties uz teorētiskās bāzes, apkopot diskursa iezīmētājus; analizēt iegūtos diskursa iezīmētājus un grupēt tos attiecīgās grupās pēc noteiktiem kritērijiem. Izstrādājot darbu padziļinātāk izprasti diskursa iezīmētāji, to funkcijas un izpausmes. Šī darba galvenie avoti, no kuriem ekscerpēti diskursa iezīmētāji, ir intervijas avīzēs un žurnālos – to struktūra ir jautājumu un atbilžu veidā –, un tāpat arī izmantoti avīžu un žurnālu raksti, kas ietver…

Changes in Body Composition, Energy Metabolites and Electrolytes During Winter Survival Training in Male Soldiers

2022

The aim of this study was to examine changes in body composition, energy metabolites and electrolytes during a 10-day winter survival training period. Two groups of male soldiers were examined: the REC group (n = 26; age 19.7 ± 1.2 years; BMI 23.9 ± 2.7) had recovery period between days 6 and 8 in the survival training, whereas the EXC group (n = 42; age 19.6 ± 0.8 years; BMI 23.1 ± 2.8) did not. The following data were collected: body composition (bioimpedance), energy balance (food diaries, heart rate variability measurements), and biomarkers (blood samples). In survival training, estimated energy balance was highly negative: −4,323 ± 1,515 kcal/d (EXC) and −4,635 ± 1,742 kcal/d (REC). Be…

The challenges of GxE research: A rejoinder

2017

On the Choice of the Extracellular Vesicles for Therapeutic Purposes

2019

Extracellular vesicles (EVs) are lipid membrane vesicles released by all human cells and are widely recognized to be involved in many cellular processes, both in physiological and pathological conditions. They are mediators of cell-cell communication, at both paracrine and systemic levels, and therefore they are active players in cell differentiation, tissue homeostasis, and organ remodeling. Due to their ability to serve as a cargo for proteins, lipids, and nucleic acids, which often reflects the cellular source, they should be considered the future of the natural nanodelivery of bio-compounds. To date, natural nanovesicles, such as exosomes, have been shown to represent a source of diseas…

New is not always costly: evidence from online processing of topic and contrast in Japanese.

2013

Two visual ERP experiments were conducted to investigate topic and contrast assigned by various cues such as discourse context, sentential position and marker during referential processing in Japanese. Experiment 1 showed that there was no N400-difference for new vs. given noun phrases (NPs) when the new NP was expected (contrastively focused) based on its preceding context and sentential position. Experiment 2 further revealed that the N400 for new NPs can be modulated by the NP’s contrastive meaning (exhausitivity) induced from the marker. Both experiments also showed that new NPs engendered an increased Late Positivity. The reduced N400 for new vs. given supports an expectation-based lin…

Traducir u omitir conectores y operadores. Simetrías/disimetrías, pérdida de la información

2018

This paper aims to contribute to the study of translation or omission of operadores and conectores in Italian and Spanish written discourse, through the analysis of a corpus extracted from the bilingual magazine Legioni e Falangi/Legiones y Falanges. (1940-43), a direct expression of an ideological and, therefore, pragmatic symmetry between two totalitarian regimes during the Second World War. Based on the case of comunque, I contrast the processes of transposition of this segnale discorsivo, revealing at the same time some syntactic and semantic (dis)symmetries between the original texts and their translation. Este trabajo pretende contribuir al estudio de la traducción u omisión de operad…

Using Corpus Linguistics as a research and training tool for Public Service Interpreting (PSI) in the legal sector

2017

Public Service Translation has for long been the ‘forgotten voice’ in PSI studies but it is arguably a valuable linguistic support for legal institutions and for training interpreters in the legal sector. Given that interpreters in the legal system in Italy often tend to ‘double-up’ as legal translators (to make a living) the line between the two is often hazy. Hybrid modalities like sight translation of legal and administrative documents is also a ‘borderline’ feature of these intertwined professions. The main aim of this paper is to describe how parallel and monolingual corpora can be used to train public service interpreters in double roles (translators, interpreters), namely by using co…

An Overview on the Use of miRNAs as Possible Forensic Biomarkers for the Diagnosis of Traumatic Brain Injury

2023

Determining the cause of death is one of the main goals of forensic pathology. However, conditions can occur in which common approaches—external inspection, autopsy, histology, etc.—might not be conclusive. With the advancement of molecular biology, several investigative techniques have been developed over the years, and the application as approaches complementary to routine procedures has proved useful in these cases. In this context, microRNA (miRNA) profiling has attracted increasing interest due to these molecules’ ability to regulate physiological and pathological processes. The evidence of differential miRNA expression in both animal models and human samples of traumatic brain injury …

Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial

2022

Background and purpose: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods: This was a phase II, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial. Participants diagnosed with definite, probable or probable laboratory-supported ALS were assigned to receive RNS60 or placebo administered for 24 weeks intravenously (375 ml) once a week and via nebul…

DIAGSOL Development of a new functional marker for B-triketone herbicides exposure in agricultural soils

2017

International audience; The-triketone herbicides are maize selective herbicides that have been largely applied in replacement of atrazine, banned in Europe in 2004. Their mode of action lays on the inhi- bition of the p-hydroxyphenylpyruvate dioxygenase (HPPD), a key enzyme of the carotenoid biosynthesis.In recent studies, we showed that within the soil bacterial community, many microorganisms possess a functional HPPD enzyme involved in tyrosine metabolism. These ”non-target or- ganisms” harbor the target of the-triketone herbicides and consequently may be affected in response to its exposure. From this point of view, the bacterial community harboring the hppd gene might be a relevant mark…