Search results for "Marr"

¿Tiene el ser humano un puesto singular en el cosmos?

2019

Do nonmelanoma skin cancers develop from extra-cutaneous stem cells?

2008

A hypothesis is presented that nonmelanoma skin cancers can develop from extra-cutaneous stem cells, and not exclusively from skin keratinocytes. This idea is supported by recent findings regarding the initiation of cancers in the digestive tract, and by a cancer stem cell model of a neoplasia. It is known that multipotent adult progenitor cells can trans-differentiate into very diverse cellular lineages and can be recruited to areas of profound tissue injury. In these settings, they might also initiate malignant transformation. Some epidemiological data and recent findings regarding mechanisms of wound healing indicate that skin cancers could also originate from bone marrow-derived or othe…

Delayed healing of chronic leg ulcers can result from impaired trafficking of bone marrow-derived precursors of keratinocytes to the skin

2006

In this paper, it is hypothesized that in chronic wounds the process of homing of bone marrow-derived precursors of keratinocytes is disturbed, and that the interaction between cutaneous T-cell attracting chemokine (CTACK/CCL27) and soluble P-selectin glycoprotein ligand-1 (PSGL-1) can be the cause of this impairment. Several studies have revealed that bone marrow-derived cells (BMDC) trans-differentiate into various cellular lineages, and probably they participate also in healing of wounded skin. Recent studies have demonstrated that BMDC can engraft into the epidermis, and probably they do not engraft into epidermis as keratinocyte stem cells, but rather as transient amplifying cells. So,…

TD-09 IL-34 promotes macrophage-mediated lupus nephritis in MRL-Faslpr mice

2018

Background Nephritis is the major cause of mortality and morbidity in patients with lupus. Macrophages (Mo) are central to kidney destruction in lupus-prone mice and patients. CSF-1, and the newly identified IL-34, mediate Mo survival and proliferation. However, IL-34 and CSF-1 differ during development and disease. While CSF-1 and IL-34 share the CSF-1 receptor (cFMS), expressed by Mo, IL-34 binds to a second receptor, Protein-Tyrosine Phosphatase ζ (PTPRZ) in inflamed kidneys. Intra-renal IL-34, cFMS, and PTPRZ are increased during the progression of lupus nephritis in MRL-Faslpr mice. Therefore, we hypothesized that IL-34 is a potential therapeutic target for lupus nephritis. Methods and…

Ylirajainen avioliitto: Puolisovalinta ja avioituminen Suomessa asuvien kurdien keskuudessa

2020

This study examines spousal choice and its gendered dimensions in the Kurdish diaspora, particularly among Kurds resident in Finland. The study focuses on a specific type of marriage migration; transnational marriage, in which migrants marry partners from their families´ homeland or from the same cultural or ethnic background within the diaspora. The research poses the following questions: What transnational courtship and marriages do Kurds resident in Finland enter into? Why do Kurds resident in Finland seek and marry a spouse transnationally? How do individuals and family members engage in negotiations for a suitable partner, in determining the compatibility criteria, and in tackling cult…

Phenolic compounds of Marrubium globosum ssp.libanoticum from Lebanon

2006

Cytokines and their effects on maturation, differentiation and migration of dendritic cells.

1996

In this review the role of cytokines in the maturation and migration of phenotypically and functionally diverse dendritic cell (DC) subpopulations is discussed and their role in the progress of differentiation from bone marrow progenitors to lymphoid DC is described. GM-CSF is the most important cytokine for the development of functional DC and acts in concert with a varying mixture of other cytokines such as IL-4, IL-1 and TNF-α to direct the development of individual DC subpopulations.

Grāmata par laulību

1938

Laulības noslēgšana un šķiršana: diplomdarbs

1931

La dirección orquestal y su dimensión social: hacia la inclusión de la mujer

2022

Por influencia de las teorías freudianas suele decirse que, en el contexto de una orquesta, la batuta representa la virilidad, al ser un elemento usado única y exclusivamente por quien ostenta el liderazgo de aquella. El director, batuta en mano, se transforma en un mediador entre el conjunto musical, la obra y el público. Sin embargo, esta analogía únicamente funciona a nivel de recepción musical y social cuando estamos ante un líder varón. El presente artículo analiza con perspectiva de género el rol del director de orquesta partiendo de su origen, como figura que surge en el siglo XIX y evoluciona hasta la actualidad. En concreto se exponen los resultados de una investigación cuyo objeti…