Search results for "Maximum-likelihood"

showing 10 items of 10 documents

Structure and function of the vacuolar Ccc1/VIT1 family of iron transporters and its regulation in fungi

2020

Iron is an essential micronutrient for most living beings since it participates as a redox active cofactor in many biological processes including cellular respiration, lipid biosynthesis, DNA replication and repair, and ribosome biogenesis and recycling. However, when present in excess, iron can participate in Fenton reactions and generate reactive oxygen species that damage cells at the level of proteins, lipids and nucleic acids. Organisms have developed different molecular strategies to protect themselves against the harmful effects of high concentrations of iron. In the case of fungi and plants, detoxification mainly occurs by importing cytosolic iron into the vacuole through the Ccc1/V…

ISC Iron-sulfur lusterCS Consistency scoreCcc1Ribosome biogenesisVacuoleReview ArticleYRE Yap response elementsBiochemistryBiotecnologia0302 clinical medicineStructural BiologyCg Candida glabrata0303 health sciencesMAFFT Multiple Alignment using Fast Fourier TransformNRAMP Natural Resistance-Associated Macrophage ProteinbiologyVIT1ChemistryMBD Metal-binding domainPlantsComputer Science ApplicationsBiochemistry030220 oncology & carcinogenesisCRD Cysteine-rich domainEg Eucalyptus grandisIron detoxificationBiotechnologyCBC CCAAT-binding core complexlcsh:BiotechnologySaccharomyces cerevisiaeVTL Vacuolar iron transporter-likeBiophysicsVIT Vacuolar iron transporterbZIP basic leucine-zipper03 medical and health sciencesFongsLipid biosynthesislcsh:TP248.13-248.65GeneticsFe IronIron transportTranscription factor030304 developmental biologyComputingMethodologies_COMPUTERGRAPHICSBLOSUM BLOcks SUbstitution MatrixTMD Transmembrane domainML Maximum-likelihoodIron regulationDNA replicationFungibiology.organism_classificationYeastYeastMetabolic pathwayH HelixHap Heme activator proteinVacuoleROS Reactive oxygen speciesFerroComputational and Structural Biotechnology Journal
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GET_PHYLOMARKERS, a software package to select optimal orthologous clusters for phylogenomics and inferring pan-genome phylogenies, used for a critic…

2018

22 Pags.- 3 Tabls.- 7 Figs. Creative Commons License Attribution 4.0 International (CC BY 4.0).

0301 basic medicineMicrobiology (medical)Computer science030106 microbiologylcsh:QR1-502GenomicsLocus (genetics)Context (language use)Computational biologyMicrobiologyGenomelcsh:Microbiologylaw.invention03 medical and health scienceschemistry.chemical_compoundPhylogeneticslawPhylogenomicsRefSeqSpecies delimitationNucleotideCladeMexicoOriginal Researchchemistry.chemical_classificationPhylogenetic treespecies-treePan-genomeStenotrophomonas maltophilia complexgenome-phylogenyphylogenetics030104 developmental biologychemistryMolecular phylogeneticsRecombinant DNAmaximum-likelihoodDNA
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Search for Cosmic Neutrino Point Sources with Four Year Data of the ANTARES Telescope

2012

In this paper, a time-integrated search for point sources of cosmic neutrinos is presented using the data collected from 2007 to 2010 by the ANTARES neutrino telescope. No statistically significant signal has been found and upper limits on the neutrino flux have been obtained. Assuming an E ¿2 n; spectrum, these flux limits are at 1-10 ¿10¿8 GeV cm¿2 s¿1 for declinations ranging from ¿90° to 40°. Limits for specific models of RX J1713.7¿3946 and Vela X, which include information on the source morphology and spectrum, are also given.

cosmic neutrinosUNIVERSEFluxVela01 natural scienceslaw.inventionHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)lawSIGNALSABSORPTION[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]MAXIMUM-LIKELIHOOD010303 astronomy & astrophysicsATMOSPHERIC MUONSPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)COSMIC cancer database[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]ASTRONOMYneutrinosastroparticle physicsFísica nuclearNeutrinoAstrophysics - High Energy Astrophysical PhenomenaREMNANT RX J1713.7-3946Particle physics[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Astrophysics::High Energy Astrophysical PhenomenaNeutrino telescope[SDU.STU]Sciences of the Universe [physics]/Earth SciencesFOS: Physical sciencesddc:500.2Telescopeneutrinos; cosmic rays; astroparticle physicscosmic rays0103 physical sciencesPoint (geometry)ALGORITHMNeutrinosDETECTORCosmic raysUNDERWATER CHERENKOV NEUTRINO TELESCOPES010308 nuclear & particles physicsAstronomy and AstrophysicsHIGH-ENERGY PHOTONSSpace and Planetary ScienceFISICA APLICADAAstroparticle physics
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An Improved Detection Technique for Cyclic-Prefixed OFDM

2010

A novel Orthogonal Frequency Division Multiplexing detection technique compatible to standard (e.g. Wireless LAN) transmitters is proposed. It features enhanced error-rate performance with flexible computational complexity and robustness to imperfect channel estimation. It is based on exploitation of the redundancy available in the cyclic prefix after cancellation of interference from the preceding block. In order to show the effectiveness of our proposal, an analysis of computational complexity and a number of comparisons to the standard per-subcarrier receiver and a previously existing method in terms of error rates are reported.

Computational complexity theoryLinear DetectionComputer Networks and CommunicationsOrthogonal frequency-division multiplexingComputer scienceSettore ING-INF/03 - TelecomunicazioniFrequency-selective channelCyclic prefixMaximum likelihood detectionSingle antenna interference cancellationRobustness (computer science)Maximum-Likelihood DetectionWireless lanStatisticsOrthogonal Frequency Division MultiplexingInterference CancellationAlgorithmComputer Science::Information Theory
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Mitochondrial phylogeography of the edible dormouse (Glis glis) in the western Palearctic region

2010

International audience; This study describes in detail the phylogeoraphic pattern Of the edible dormouse (Glis glis) a European rodent With pronounced hibernating behavior We Used sequences of 831 base pairs of the mitochondrial DNA cytochrome-b gene from 130 edible dormice collected at 43 localities (throughout Its distribution. Our results reveal presence of 3 main haplogroups: Sicilian, South Italian (restricted to the Calabrian region) (a widespread lineage corresponding to all remaining western, central. and eastern European populations). Examination of paleontological data confirms refugial regions for G,Its in the 3 Mediterranean peninsulas, although overall low genetic diversity is …

0106 biological sciencesEUROPEpostglacial colonization[SDV]Life Sciences [q-bio]ZoologyGENETIC CONSEQUENCESmitochondrial DNABiologyphylogeography010603 evolutionary biology01 natural sciencesHaplogroup03 medical and health sciencesRefugium (population biology)biology.animalGeneticsGLACIAL REFUGIAGenetic variabilitydormouse Europe glacial refugia Glis glis mitochondrial DNA phylogeography postglacial colonizationWOODMOUSE APODEMUS-SYLVATICUSDormouseMAXIMUM-LIKELIHOODEcology Evolution Behavior and Systematics030304 developmental biologyNature and Landscape ConservationEdible dormouse0303 health sciencesGenetic diversityEcologyPOPULATION-GROWTHEcology15. Life on landbiology.organism_classificationDNA-SEQUENCESEastern europeandormousePhylogeographyVOLE MICROTUS-ARVALIS[SDE]Environmental SciencesAnimal Science and ZoologyICE AGESGlis glis
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New insight into the colonization processes of common voles: inferences from molecular and fossil evidence.

2008

Biologie et Gestion des Populations, Campus International de Baillarguet, Montferrier/Lez, FranceElucidating the colonization processes associated with Quaternary climatic cycles is important in order to understand the distribution of biodiversity and the evolutionary potential of temperate plant and animal species. In Europe, general evolutionary scenarios have been defined from genetic evidence. Recently, these scenarios have been challenged with genetic as well as fossil data. The origins of the modern distributions of most temperate plant and animal species could predate the Last Glacial Maximum. The glacial survival of such populations may have occurred in either southern (Mediterranea…

0106 biological sciences[ SDE.BE.BIOD ] Environmental Sciences/Biodiversity and Ecology/domain_sde.be.biodBiodiversitylcsh:Medicine[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy01 natural sciencesbiodiversitéEvolutionary Biology/Animal GeneticsMaximum-LikelihoodControl RegionGlacial periodévolutionlcsh:SciencePhylogenyévolution biologiqueMismatch Distributionchangement climatique0303 health sciencesMultidisciplinarybiologyArvicolinaeFossilsEcology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]mammifèreFossil RecordCytochromes bEuropePhylogeographyHabitatResearch ArticleEvolutionary Biology/PaleontologyGene FlowClimatic ChangesGenetic SpeciationcolonisationMolecular DatingCytochrome b010603 evolutionary biologyQuaternary03 medical and health sciencesAnimalsMicrotusDemography030304 developmental biologyBayesian ApproachEvolutionary Biology/Evolutionary and Comparative GeneticsrongeurHuman evolutionary geneticslcsh:RGenetic Variation[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologySequence Analysis DNAmicrotus arvalis15. Life on landbiology.organism_classificationBiogeographic TraitsPhylogeographyGenetic SpeciationBiological dispersalAnimal Migrationlcsh:QCommon Vole
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Phylogeography and Molecular Evolution of Potato virus Y

2012

Potato virus Y (PVY) is an important plant pathogen, whose host range includes economically important crops such as potato, tobacco, tomato, and pepper. PVY presents three main strains (PVYO, PVYN and PVYC) and several recombinant forms. PVY has a worldwide distribution, yet the mechanisms that promote and maintain its population structure and genetic diversity are still unclear. In this study, we used a pool of 77 complete PVY genomes from isolates collected worldwide. After removing the effect of recombination in our data set, we used Bayesian techniques to study the influence of geography and host species in both PVY population structure and dynamics. We have also performed selection and…

0106 biological sciencesEvolutionary GeneticsAmino-acid sitesSelective constraintsPotyviruslcsh:Medicine01 natural sciencesAmino-Acid SitesRecombinant strainPlant RNA virusesNegative selectionMaximum-Likelihoodlcsh:Sciencepathologie végétaleSelective ConstraintsPhylogenyGenetics0303 health sciencesCoat proteinMultidisciplinaryNatural selectionVegetal BiologybiologyEcologyGenetic-structurePotyvirusfood and beveragesEuropePhylogeneticsVenous necrosisPhylogeographyPotato virus YBiogeographyVenous NecrosisSequence AnalysisResearch ArticlePlant RNA VirusesGenome ViralMicrobiologyEvolution Molecular03 medical and health sciencesGenetic-StructureMolecular evolutionVirologyMosaic-virus[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyEvolutionary SystematicsBiology030304 developmental biologySolanum tuberosumGenetic diversityEvolutionary BiologyMosaic virusHost (biology)Maximum-likelihoodlcsh:RComputational Biologyvirus à de la pomme de terreBayes Theoremlégumebiology.organism_classificationMutational analysisMosaic-VirusMutational AnalysisEvolutionary EcologyRecombinant StrainNorth Americalcsh:QBiologie végétalePopulation Genetics010606 plant biology & botany
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Taxas de substituições das Annonaceas: uma perspectiva do modelo códon

2014

The Annonaceae includes cultivated species of economic interest and represents an important source of information for better understanding the evolution of tropical rainforests. In phylogenetic analyses of DNA sequence data that are used to address evolutionary questions, it is imperative to use appropriate statistical models. Annonaceae are cases in point: Two sister clades, the subfamilies Annonoideae and Malmeoideae, contain the majority of Annonaceae species diversity. The Annonoideae generally show a greater degree of sequence divergence compared to the Malmeoideae, resulting in stark differences in branch lengths in phylogenetic trees. Uncertainty in how to interpret and analyse these…

Nonsynonymous substitutionmodelo códondiversificationcomprimentos dos ramosSynonymous substitution ratecharactersfilogenéticaAnnonaceaePlant Sciencelcsh:Plant cultureDNA sequencinggeneraMolecular evolutionPhylogeneticsCodon modelsphylogeny reconstructionLaboratorium voor Moleculaire Biologielcsh:SB1-1110patternsCladeNon-synonymous substitutionNdhFGeneticsflowering plantsPhylogenetic treebiologyhistorical biogeographymolecular evolutionBiology and Life Sciencesbiology.organism_classificationBiosystematiekratePhylogeneticsAnnonaceaesubstituições não-sinônimassubstituições sinônimasBiosystematicsBranch lengthsNon-synonymous substitution ratemaximum-likelihoodLaboratory of Molecular BiologyEPSAgronomy and Crop ScienceFood Sciencenucleotide substitution
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Estimation of ordered response models with sample selection

2011

We introduce two new Stata commands for the estimation of an ordered response model with sample selection. The opsel command uses a standard maximum-likelihood approach to fit a parametric specification of the model where errors are assumed to follow a bivariate Gaussian distribution. The snpopsel command uses the semi-nonparametric approach of Gallant and Nychka (1987, Econometrica 55: 363–390) to fit a semiparametric specification of the model where the bivariate density function of the errors is approximated by a Hermite polynomial expansion. The snpopsel command extends the set of Stata routines for semi-nonparametric estimation of discrete response models. Compared to the other semi-n…

EstimationSample selectionHermite polynomialsResponse modelComputer scienceEstimatorSettore SECS-P/05 - EconometriaProbability density functionBivariate analysisst0226 opsel opsel postestimation sneop sneop postestimation snp2 snp2 postestimation snp2s snp2s postestimation snpopsel snpopsel postestimation snp snp postestimation ordered response models sample selection parametric maximum-likelihood estimation semi-nonparametric estimationSet (abstract data type)Mathematics (miscellaneous)StatisticsSettore SECS-P/01 - Economia PoliticaAlgorithmMathematicsParametric statistics
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Emergence and Phylodynamics of Citrus tristeza virus in Sicily, Italy

2013

Citrus tristeza virus (CTV) outbreaks were detected in Sicily island, Italy for the first time in 2002. To gain insight into the evolutionary forces driving the emergence and phylogeography of these CTV populations, we determined and analyzed the nucleotide sequences of the p20 gene from 108 CTV isolates collected from 2002 to 2009. Bayesian phylogenetic analysis revealed that mild and severe CTV isolates belonging to five different clades (lineages) were introduced in Sicily in 2002. Phylogeographic analysis showed that four lineages co-circulated in the main citrus growing area located in Eastern Sicily. However, only one lineage (composed of mild isolates) spread to distant areas of Sici…

Nonsynonymous substitutionCitrusGenetic-variationLineage (evolution)Population Dynamicslcsh:MedicinePopulation geneticsPlant Sciencelcsh:SciencePhylogenetic analysesPhylogenyGeneticsMultidisciplinarybiologyPhylogenetic treeGeographyCitrus tristeza virusAgriculturePhylogeneticsItalyRNA ViralEvolutionary dynamicsCross-protectionSequence AnalysisResearch ArticleClosterovirusDNA ComplementaryMolecular Sequence DataPlant PathogensCropsMicrobiologyViral EvolutionFruitsGenetic driftSpecies SpecificityVirologyMosaic-virusGenetic variationCTV Phylodynamics SicilyEvolutionary SystematicsPopulation-structureHost passageBiologyPlant DiseasesEvolutionary BiologyMaximum-likelihoodlcsh:RSettore AGR/12 - Patologia VegetaleComputational BiologyGenetic VariationBayes TheoremSequence Analysis DNAPlant Pathologybiology.organism_classificationAgronomyViral phylodynamicsDNA polymorphismEvolutionary biologyMolecular evolutionlcsh:Q
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