Search results for "Mechanism"
showing 10 items of 1835 documents
Organocatalysts Fold to Generate an Active Site Pocket for the Mannich Reaction
2017
Catalysts containing urea, thiourea and tertiary amine groups fold into a three-dimensional organized structure in solution both in the absence as well as in the presence of substrates or substrate analogues, as indicated by solution NMR and computational studies. These foldamer catalysts promote Mannich reactions with both aliphatic and aromatic imines and malonate esters. Hammett plot and secondary kinetic isotope effects provide evidence for the C-C bond forming event as the turnoverlimiting step of the Mannich reaction. Computational studies suggest two viable pathways for the C-C bond formation step, differing in the activation modes of the malonate and imine substrates. The results sh…
Effect of Mg2+ ions on competitive metal ions adsorption/desorption on magnesium ferrite : mechanism, reusability and stability studies
2021
The adsorption behavior of magnesium ferrite in single- and multicomponent metal ions solutions in the presence of Mg2+ ions were studied. A dramatic decrease in the adsorption capacity of magnesium ferrite towards Mn2+, Co2+, and Ni2+ ions for comparison study of single- and multicomponent solutions was established. The affinity of the sorbent in accordance with the maximum sorption capacities increases in the following order Cu2+ > Co2+ > Ni2+ > Mn2+. High efficiency of magnesium ferrite regeneration (~100%) with aqueous solutions of magnesium chloride in the concentration range of 0.001-0.1 M was shown. The low degree of toxic metal ions desorption combined with XRD, IR spectroscopy, and…
Digital Education For All: Multi-University Study of Increasing Competent Student Admissions at Scale
2022
An indubitable way to put learning at scale in practice is to implement Massive Open Online Courses, or MOOCs. When a wide-enough portfolio of them is available, new applications arise. For instance, university admissions in Finland, where this study was conducted, have traditionally been based on students' grades in high school studies, an entrance examination, or a combination of both. A minority of students have been accepted through an open university admission path where students can get a study right if they complete enough university course credits with a high enough grade in a given time frame. In this work, we report results from a multi-university project in which the open univers…
Clustering-triggered endocytic pathway of α2β1 integrin
2012
The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice
2018
The beneficial effects of probiotics on immune-based pathologies such as inflammatory bowel disease (IBD) have been well reported. However, their exact mechanisms have not been fully elucidated. Few studies have focused on the impact of probiotics on the composition of the colonic microbiota. The aim of the present study was to correlate the intestinal anti-inflammatory activity of the probiotic Escherichia coli Nissle 1917 (EcN) in the dextran sodium sulfate (DSS) model of mouse colitis with the changes induced in colonic microbiota populations. EcN prevented the DSSinduced colonic damage, as evidenced by lower disease activity index (DAI) values and colonic weight/length ratio, when compa…
Reciprocity, matching and conditional cooperation in two public goods games
2005
Previous experimental and empirical evidence has identified social preferences in the voluntary provision of public goods. A number of competing models of such preferences have been proposed. We provide evidence for one model of behavior in these games, reciprocity (or matching, or conditional cooperation). Consistent with previous research, we find that participants in the voluntary contribution mechanism attempt to match the contributions of others in their group. We also examine participants in a related game with different equilibria, the weakest-link mechanism. Here, in contrast, participants contribute so as to match the minimum contribution of others in their group.
Two traditions of cognitive sociology : an analysis and assessment of their cognitive and methodological assumptions
2022
Cognitive sociology has been split into cultural and interdisciplinary traditions that position themselves differently in relation to the cognitive sciences and make incompatible assumptions about cognition. This article provides an analysis and assessment of the cognitive and methodological assumptions of these two traditions from the perspective of the mechanistic theory of explanation. We argue that while the cultural tradition of cognitive sociology has provided important descriptions about how human cognition varies across cultural groups and historical periods, it has not opened up the black box of cognitive mechanisms that produce and sustain this variation. This means that its expla…
Chinese students' perceptions of cooperative learning in Finland
2015
International students from China continue to have a strong presence in European tertiary institutions, however, only a limited number of studies can be found about their learning experiences and their perceptions towards western educational practices. How Chinese students in Finland perceive cooperative learning is the focus of this study, while different education cultures between China and Finland is identified as the dominant element that may determine students’ beliefs and their choices of coping strategies when confronting challenges during cooperative learning practice. Qualitative data from 10 participants were collected through interviews conducted in Chinese. Based on participants…
Uusiutuva energia ja energiajärjestelmän konsensus : mekanisminen näkökulma liikenteen biopolttoaineiden ja syöttötariffin käyttöönottoon Suomessa
2014
Pain neuroscience education and physical exercise for patients with chronic spinal pain in primary healthcare: a randomised trial protocol.
2019
AbstractBackgroundChronic musculoskeletal pain affects more than 20% of the population, and the prevalence is increasing, causing suffering, loss of quality of life, disability, and an enormous expenditure on healthcare resources. The most common location for chronic pain is the spine. Many of the treatments used are mainly passive (pharmacological and invasive) and poor outcomes. The treatments currently applied in the public health system do not comply with the recommendations of the main clinical practice guidelines, which suggest the use of educational measures and physical exercise as the first-line treatment. A protocol based on active coping strategies is described, which will be eva…