Search results for "Mechanism"
showing 10 items of 1835 documents
Tractional Motion Machines extend GPAC-generable functions
2012
In late 17th century there appeared the Tractional Motion instruments, mechanical devices which plot the curves solving differential equations by the management of the tangent. In early 20th century Vannevar Bush’s Differential Analyzer got the same aim: in this paper we’ll compare the Differential Analyzer mathematical model (the Shannon’s General Purpose Analog Computer, or GPAC) with the Tractional Motion Machine potentials. Even if we will not arrive in defining the class of the functions generated by Tractional Motion Machines, we’ll see how this class will strictly extend the GPAC-generable functions.
Don't tell us: the demand for secretive bahaviour
2009
International audience
Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy
2015
ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.
A Novel Pathophysiological Mechanism Contributing to Trigeminal Neuralgia
2016
Trigeminal neuralgia (TN) is a form of neuropathic pain that affects the fifth cranial nerve, the most widely distributed nerve in the head. Although TN has been associated with a variety of pathological conditions, neurovascular compression on the trigeminal nerve, as it exits the brain stem, is the most frequent reported cause. This compression provides a progressive demyelination of the nerve and a subsequent aberrant neural transmission. Although several studies have clarified some physiopathological mechanisms underlying TN, the molecular basis remains vague. Very recently the substitution of methionine 136 by valine (MET126Val) in sodium channel Nav1.6 in a case study of typical TN ha…
On the mechanism of imine elimination from Fischer tungsten carbene complexes
2016
(Aminoferrocenyl)(ferrocenyl)carbene(pentacarbonyl)tungsten(0) (CO)5W=C(NHFc)Fc (W(CO)5(E-2)) is synthesized by nucleophilic substitution of the ethoxy group of (CO)5W=C(OEt)Fc (M(CO)5(1Et)) by ferrocenyl amide Fc-NH– (Fc = ferrocenyl). W(CO)5(E-2) thermally and photochemically eliminates bulky E-1,2-diferrocenylimine (E-3) via a formal 1,2-H shift from the N to the carbene C atom. Kinetic and mechanistic studies to the formation of imine E-3 are performed by NMR, IR and UV–vis spectroscopy and liquid injection field desorption ionization (LIFDI) mass spectrometry as well as by trapping experiments for low-coordinate tungsten complexes with triphenylphosphane. W(CO)5(E-2) decays thermally i…
Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures.
2014
Formation of superstructures in protein aggregation processes has been indicated as a general pathway for several proteins, possibly playing a role in human pathologies. There is a severe lack of knowledge on the origin of such species in terms of both mechanisms of formation and structural features. We use equine lysozyme as a model protein, and by combining spectroscopic techniques and microscopy with X-ray fiber diffraction and ab initio modeling of Small Angle X-ray Scattering data, we isolate the partially unfolded state from which one of these superstructures (i.e., particulate) originates. We reveal the low-resolution structure of the unfolded state and its mechanism of formation, hi…
Begripligheten av finskspråkiga gymnasisters svenska uttal: lyssnarvärderingar
2018

 
 
 The aim of this study is to investigate how comprehensible L1 Finnish speakers’ L2 Swedish is considered to be and whether any listener- or speaker-specific background factors relating to the comprehensibility judgements can be found. The research material consists of Swedish read-aloud texts by 21 Finnish-speaking upper secondary school students. Judgements are given by 64 native Swedish-speakers (Finland-Swedish n = 35, Sweden-Swedish n = 29) using a verbalized scale from 1 to 7. The study shows that L2 Swedish, pronounced by L1 Finnish speakers, is on average considered to be comprehensible but the listener has to concentrate closely. Both Finland-Swedish and Sweden-…
Kodolieroču neizplatīšanas uzraudzības un pārbaudes mehānismi: Irānas (2002 – 2015) gadījuma analīze
2020
Maģistra darbs “Kodolieroču neizplatīšanas uzraudzības un pārbaudes mehānismi: Irānas (2002 – 2015) gadījuma analīze” analizē Irānas kodolprogrammas uzraudzību laika posmā no 2002. līdz 2015. gadam. Pētījuma mērķis ir noskaidrot, kāpēc Irānas kodolprogrammas statuss tiek regulāri apšaubīts. Darba teorētisko ietvaru veido kodolieroču neizplatīšanas režīma galveno komponentu analīze. Šī gadījuma analīzē tiek izmantotas kvalitatīvās pētniecības metodes – oficiālo ziņojumu, dokumentu un līgumu kontentanalīze, kā arī tiek veikta akadēmisko pētījumu izpēte. Pētījuma rezultātā tiek izdarīti secinājumi, kā iesaistītās puses kodolieroču neizplatīšanas uzraudzības un pārbaudes ietvaros reaģē uz tām s…
Perhepäivähoito- ja päiväkoti-instituutio varhaiskasvatuksen kunnallisten viranhaltijoiden puheessa
2022
Tutkimuksessa tarkasteltiin perhepäivähoito- ja päiväkoti-instituutioiden tuottamista varhaiskasvatuksesta vastaavien kunnallisten viranhaltijoiden puheessa. Tutkimus tehtiin kymmenessä suomalaisessa kunnassa, ja aineistona käytettiin teemahaastatteluja (N =42). Perhepäivähoito ja päiväkotitoiminta ymmärrettiin diskursiivisen institutionalismin näkökulmasta sosiaalisina käytäntöinä, joiden merkitykset ilmenevät ja muuttuvat varhaiskasvatuksen instituutioiden kielenkäytössä. Aineistoa analysoitiin diskursiivisesti, ja puheesta erotettiin vaihtelevia tapoja puhua perhepäivähoidosta ia päiväkotitoiminnasta. Löydetyissä puhetavoissa perhepäivähoidolle ja päiväkotitoiminnalle tuotettiin erilaise…
Multimodal Aposematic Defenses Through the Predation Sequence
2021
Aposematic organisms warn predators of their unprofitability using a combination of defenses, including visual warning signals, startling sounds, noxious odors, or aversive tastes. Using multiple lines of defense can help prey avoid predators by stimulating multiple senses and/or by acting at different stages of predation. We tested the efficacy of three lines of defense (color, smell, taste) during the predation sequence of aposematic wood tiger moths (Arctia plantaginis) using blue tit (Cyanistes caeruleus) predators. Moths with two hindwing phenotypes (genotypes: WW/Wy = white, yy = yellow) were manipulated to have defense fluid with aversive smell (methoxypyrazines), body tissues with a…