Search results for "Medical prescription"

Colorectal cancer: pharmacogenetics support for the correct drug prescription

2019

Pharmacogenetics (PGx) in clinical practice is a tool that the clinician can use to guide, in a personalized way, the most suitable treatment that will be administered to the patient. The objective of this review is to summarize in a practical and accessible rational way, the advances that currently exist for the application of PGx in colorectal cancer chemotherapy management through the study of the patients’ germline polymorphisms. To define the polymorphisms that can be applied, we rely on three fundamental cornerstones: the recommendations of drug regulatory agencies; the implementation guidelines prepared by expert consortia in PGx and information from clinical annotations (the drug/p…

Herbal hepatotoxicity: a hidden epidemic

2011

Complementary and alternative therapies, including herbal products, have become increasingly popular in the general population and among patients and physicians. Regulations and pharmacovigilance regarding herbal drugs are still incomplete and need to be improved. In fact, herbals are commonly marketed on the Internet, and in many countries they are sold as food supplements, which are beyond the control of drug regulatory agencies. In Europe and the U.S., reports of hepatotoxicity from these products, including those advertised for liver diseases, are accumulating. Many herbal drugs are also commonly used in children, and in women during pregnancy and lactation, because they are believed to…

SPCCTDM, a Catalogue for Analysis of Therapeutic Drug Monitoring Related Contents in the Drug Prescription Information

2010

Therapeutic drug monitoring (TDM) has consistently been shown to be useful for optimization of drug therapy. For the first time, a method has been developed for the text analysis of TDM in SPCs in that a catalogue SPC-ContentTDM (SPCCTDM) provides a codification of the content of TDM in SPCs. It consists of six structure-related items (dose, adverse drug reactions, drug interactions, overdose, pregnancy/breast feeding, and pharmacokinetics) according to implicit or explicit references to TDM in paragraphs of the SPC, and four theory-guided items according to the information about ranges of plasma concentrations and a recommendation of TDM in the SPC. The catalogue is regarded as valid for t…

Pharmaceutical promotion and guided-prescription in low- and middle-income countries: A need for new regulations.

2020

Are byline biases an issue of the past? The effect of author’s gender and emotion norm prescriptions on the evaluation of news articles on gender equ…

2021

When female journalists write about issues of gender equality, they often become the target of incivility and their work is devaluated. Research has investigated such devaluations based on journalists’ gender under the scope of byline biases, analysing if it matters to readers whether a news piece is authored by a male or female journalist. In this paper, we set out to study if gender byline biases occur when journalists write about gender equality. As gender attributions become particularly salient through the presentation of gendered emotion norms, we also inquire in how it matters for readers’ interest in reading such an article and the attributed credibility of the author when an artic…

Physical activity prescription from primary care: impact on self steem and quality of life

2020

Abstract Objective To evaluate the benefit in terms of self-esteem, quality of life (QoL) and health perception, in a physical activity (FA) prescription intervention from Primary Care, after three months. Methods Quasi-experimental study before (T0) -after (T1) without a control group, for the evaluation of the pilot phase of the CAS program, implemented (December 2017-May 2018) in 5 primary health centers in Valencia. The questionnaire (T0) was completed with social information, self-esteem (Rosemberg), and QoL (Euroqol-5D, including health perception (HP)). The FA was prescribed with specific hours and days and the participation was monitorized. Three months after starting the FA, the pa…

Évaluation de la prescription du furosémide chez la personne âgée de 75 ans et plus dans un service de gériatrie aiguë

2018

Resume Introduction Le furosemide est tres prescrit en France. Il serait responsable d’effets indesirables non negligeables surtout chez la personne âgee. Afin de limiter son mesusage et un surcout pour la securite sociale, la Societe europeenne de cardiologie a edite des recommandations de prescription strictes. Nous avons conduit une etude dans une population âgee dont l’objectif principal etait de determiner le taux de prescription du furosemide chez la personne âgee hors recommandations. Methode Il s’agissait d’une etude prospective, monocentrique et observationnelle portant sur des personnes d’âge ≥ 75 ans, admises dans un service de geriatrie aigue sur une periode de 6 mois. La preval…

Disease awareness campaigns in printed and online media in Latvia: cross-sectional study on consistency with WHO ethical criteria for medicinal drug …

2018

Background European legislation prohibits direct-to-consumer advertising of prescription medicines, but allows drug manufacturers to provide information to the public on health and diseases. Our aim was to measure the frequency of disease awareness campaigns in Latvian media and assess their compliance with international and European standards. Methods Materials on health/disease and treatments were collected between April and September 2015 from 12 newspapers and magazines and six online portals. Disease awareness campaigns were assessed using a previously developed instrument based on the WHO Ethical Criteria for Medicinal Drug promotion and European standards (EU law and pharmaceutical i…

Assessment of a reconciliation and information programme for heart transplant patients

2010

Abstract Introduction The objective is to assess a pharmaceutical care programme for heart transplant patients upon patient admission and discharge. Material and methods Observational study of heart transplant patients, performed during the first quarter of 2007. Upon admission, the patient was interviewed regarding home treatments, adherence, allergies, and adverse effects, his/her prescriptions were compared with the last discharge report (drug reconciliation). At time of discharge, treatment was checked against the last hospital prescription (reconciliation) and an informative report was drawn up and personally delivered to the patient. Subsequently, a satisfaction questionnaire was carr…

Observational Study of Antibiotic Usage at the Children’s Clinical University Hospital in Riga, Latvia

2018

Background and objectives: Many pediatric patients have been treated with antibiotics during their hospitalization. There is a need to improve antibiotic prescribing for pediatric patients because many of these prescriptions are inappropriate. Antibiotic consumption analysis was conducted at the Children&rsquo