Search results for "Medulla"

showing 10 items of 164 documents

New intramedullary locking nail for olecranon fracture fixation--an in vitro biomechanical comparison with tension band wiring.

2010

The aim of this study was to determine the difference in displacement of a newly designed intramedullary olecranon fracture fixation device compared with multifilament tension band wiring after 4 cycles and 300 cycles of dynamic continuous loading.In eight pairs of fresh-frozen cadaver ulnae, oblique olecranon fractures were created and stabilized using either newly designed intramedullary olecranon nail or multifilament tension band wiring. The specimens were then subjected to continuous dynamic loading (from 25 N to 200 N) using matched pairs of cadaveric upper extremities. The Wilcoxon test was used to determine statistical differences of the displacement in the fracture gap.After 4 cycl…

MaleBone NailsCritical Care and Intensive Care MedicineProsthesis Designlaw.inventionIntramedullary rodFixation (surgical)lawFracture fixationElbow JointmedicineHumansDisplacement (orthopedic surgery)Olecranon ProcessRange of Motion ArticularBone WiresAgedOrthodonticsAged 80 and overbusiness.industryTension band wiringMiddle Agedmedicine.diseaseUlna FracturesBiomechanical PhenomenaFracture Fixation Intramedullarymedicine.anatomical_structureOlecranon fractureNail (anatomy)SurgeryFemaleStress MechanicalbusinessElbow InjuriesBone WiresThe Journal of trauma
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Clinical performance of a new medullary humeral nail: antegrade versus retrograde insertion.

2001

Objective A new intramedullary nail system for humeral shaft fractures is evaluated to determine whether retrograde nailing is as reliable as antegrade nailing. Study design Prospective multicenter nonrandomized clinical study. Patients Eighty-four patients with acute humeral shaft fractures were nailed with the new unreamed humeral nail (UHN) system. Fifty-seven nails were introduced retrogradely, and twenty-seven antegradely. Bone healing and functional outcome were the follow-up parameters. Results The ratio of perioperative complications was equivalent for both groups, but one shaft fracture and three fractures or fissures at the entry point occurred in the group with retrograde nail in…

AdultMalemedicine.medical_specialtyHumeral FracturesMedullary cavityAdolescentBone healingBone Nailslaw.inventionIntramedullary rodlawFracture fixationmedicineHumansMulticenter Studies as TopicOrthopedics and Sports MedicineHumerusProspective Studiesskin and connective tissue diseasesAgedAged 80 and overFracture HealingOsteosynthesisintegumentary systembusiness.industryGeneral MedicineMiddle AgedSurgeryFracture Fixation IntramedullaryRadiographyDiaphysismedicine.anatomical_structureOrthopedic surgerySurgeryFemalebusinessJournal of orthopaedic trauma
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The neuro-B cell link of peptidergic innervation in the Bursa Fabricii

1991

The Bursa Fabricii, restricted to birds, specifically provides the microenvironment for B-cell maturation. The presence of nerve fibers containing immunopotent neuropeptides in immune organs opens interesting perspectives on the understanding of neuroimmune communication. As an organ for the development of only B-lymphocytes is not known in mammals, the contribution of a peptidergic innervation to the microenvironment of B-cells is not known. Therefore, we studied the peptidergic innervation of the Bursa Fabricii as an organ of B-cell maturation. Four different neuropeptides were found in nerve fibers of the Bursa Fabricii: tachykinins (TK), vasoactive intestinal peptide (VIP), galanin (GAL…

medicine.medical_specialtyNeuroimmunomodulationCalcitonin Gene-Related PeptideImmunologyVasoactive intestinal peptideNeuropeptideGalaninNerve fiberBiologyCalcitonin gene-related peptideMonocytesImmunoenzyme TechniquesBehavioral NeuroscienceBursa of FabriciusNerve FibersTachykininsInternal medicinemedicineAnimalsGalaninMedullaB cellB-LymphocytesEndocrine and Autonomic SystemsMacrophagesNeuropeptidesCell DifferentiationCell biologyEndocrinologymedicine.anatomical_structurePeripheral nervous systemPeptidesChickensVasoactive Intestinal PeptideBrain, Behavior, and Immunity
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Spinal Intradural Intramedullary Dissemination in the Absence of Intracranial Relapse of a Previously Radically Treated Temporal Lobe Glioblastoma Mu…

2017

Intracranial glioblastoma multiforme (GBM) constitutes the most frequent and unfortunately aggressive primary central nervous system malignancy. Despite the high tendency of these tumors to show local relapse within the brain after primary therapy, dissemination into the spinal axis is an infrequent event. If spinal metastases occur they are leptomeningeal in the vast majority of cases and always in the context of intracranial progressive disease. Spinal intramedullary metastases of intracranial GBM have rarely been described to date. We report the unique case of a young woman with subacute progressive paraparesis due to spinal intramedullary metastases of a temporal lobe GBM despite the re…

medicine.medical_specialtyPathologymedicine.medical_treatmentCentral nervous systemSpinal intradural intramedullary disseminationContext (language use)Case ReportMalignancylcsh:RC254-282Temporal lobelaw.inventionIntramedullary rod03 medical and health sciences0302 clinical medicinelawmedicineChemotherapybusiness.industrymedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.anatomical_structureOncology030220 oncology & carcinogenesisTemporal lobe glioblastoma multiformeRadiologybusiness030217 neurology & neurosurgeryProgressive diseaseGlioblastomaCase Reports in Oncology
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Differential Effects of Exercise on Tibial Shaft Marrow Density in Young Female Athletes

2013

Increased mechanical loading can promote the preferential differentiation of bone marrow mesenchymal stem cells to osteoblastogenesis, but it is not known whether long-term bone strength-enhancing exercise in humans can reduce marrow adiposity.Our objective was to examine whether bone marrow density (MaD), as an estimate of marrow adiposity 1) differs between young female athletes with contrasting loading histories and bone strengths and 2) is an independent predictor of bone strength at the weight-bearing tibia.Mid-tibial MaD, cortical area (CoA), total area, medullary area, strength strain index (SSI), and cortical volumetric bone mineral density (vBMD) (total, endocortical, midcortical, …

Adultmedicine.medical_specialtyAdolescentChemical PhenomenaMedullary cavityEndocrinology Diabetes and MetabolismAdipocytes WhiteClinical BiochemistryBone Marrow CellsContext (language use)BiochemistryWeight-BearingYoung AdultEndocrinologyBone DensityBone MarrowOsteogenesisInternal medicinemedicineHumansTibiaQuantitative computed tomographyExerciseAdiposityBone mineralOsteoblastsTibiabiologymedicine.diagnostic_testAthletesbusiness.industryBiochemistry (medical)Adolescent Developmentbiology.organism_classificationPeripheralEndocrinologymedicine.anatomical_structureAthletesFemaleDiaphysesBone marrowTomography X-Ray ComputedbusinessThe Journal of Clinical Endocrinology & Metabolism
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Design of a new tibial intramedullary nail

2011

FEM analysis redesign intramedullary nailSettore ING-IND/15 - Disegno E Metodi Dell'Ingegneria Industriale
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Dynamische Analyse von Osteosynthesen am Olecranon: ein in-vitro Vergleich zweier Osteosynthesesysteme / Dynamic analysis of olecranon osteosyntheses…

2008

INTRODUCTION The aim of the present study was to develop a test setup with continuous angle alteration to imitate elbow joint motion for the mechanical evaluation of tension band wiring and a newly designed intramedullary nail. MATERIALS AND METHODS The servo-pneumatical test stand worked with a rotational angle-adjusted and a linear force-adjusted engine. The fracture model was dynamically tested under cyclic loading imitating elbow joint motion. In total, 14 fresh cadaver upper extremities underwent olecranon fracture by means of transverse osteotomy and were assigned to two groups: tension band wiring and intramedullary nailing. There was a continuous angle alteration between 0 and 1000 …

OrthodonticsMaterials scienceOsteosynthesisTension band wiringOlecranonElbowBiomedical Engineeringmedicine.diseaselaw.inventionIntramedullary rodmedicine.anatomical_structureOlecranon fracturelawFracture fixationmedicineDisplacement (orthopedic surgery)Biomedizinische Technik/Biomedical Engineering
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Malignant epithelial/exocrine tumors of the pancreas

2020

Summary Pancreatic malignant exocrine tumors represent the most important cause of cancer-related death for pancreatic neoplasms. The most common tumor type in this category is represented by pancreatic ductal adenocarcinoma (PDAC), an ill defined, stroma-rich, scirrhous neoplasm with glandular differentiation. Here we present the relevant characteristics of the most important PDAC variants, namely adenosquamous carcinoma, colloid carcinoma, undifferentiated carcinoma, undifferentiated carcinoma with osteoclast-like giant cells, signet ring carcinoma, medullary carcinoma and hepatoid carcinoma. The other categories of malignant exocrine tumors, characterized by fleshy, stroma-poor, circumsc…

acinarPathologymedicine.medical_specialtyAdenosquamous carcinomapancreatic cancerPancreatoblastomapancreatic ductal adenocarcinomaReviewAdenocarcinomaGlandular DifferentiationPathology and Forensic MedicinePancreatic cancersolid pseudopapillary.medicineCarcinomaNeoplasmHumansacinar; pancreatic cancer; pancreatic ductal adenocarcinoma; PDAC; solid pseudopapillaryPancreasbusiness.industryPDACPDAC; acinar; pancreatic cancer; pancreatic ductal adenocarcinoma; solid pseudopapillarymedicine.diseasePancreas ExocrinePancreatic Neoplasmssolid pseudopapillarymedicine.anatomical_structureMedullary carcinomaPancreasbusinessCarcinoma Pancreatic Ductal
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A Clinical Comparison between the Gamma® and the Claufitt® Nails in Unstable Proximal Femoral Fractures

2007

Purpose To assess the differences that exist between two intramedullary osteosynthesis systems for the treatment of unstable proximal femoral fractures in an attempt to find out whether the use of an antirotation screw improves the final result. Materials and methods A retrospective study was carried out to analyze the plcement and clinical evolution of both intramedullary nailing systems (Gamma ® y Claufitt ® ). The patients’ medium-term functional status was evaluated and benchmarked against the characteristics of the population served by our University Hospital. A final database was obtained made up of 43 cases of Claufitt ® that met the criteria of our study. A functional assessment sys…

Orthodonticseducation.field_of_studyOsteosynthesisbusiness.industryPopulationRetrospective cohort studyUniversity hospitallaw.inventionIntramedullary rodlawEvaluation methodsMedicineOrthopedics and Sports MedicineSurgeryFunctional statuseducationbusinessRevista Española de Cirugía Ortopédica y Traumatología (English Edition)
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Replication of herpes simplex virus type 1 and 2 in the medulla of the adrenal gland after vaginal infection of mice.

1996

After vaginal infections of mice with neuroinvasive strains of herpes simplex virus type 1 and 2 (HSV-1, HSV-2) virus replicates in the epithelium of the vagina, in the paravaginal ganglia, in the spinal cord and finally in the brain and in the adrenal glands. However, viral antigens could be demonstrated only in the medulla of the adrenal glands but not in the cortex, as assessed by immunohistochemistry (IHC). HSV could not be isolated from liver, spleen, uterus, and ovaries. This contrasts to the intraperitoneal (i.p) route of infection with replication in different visceral organs including the adrenal gland's cortex.

virusesHerpesvirus 2 HumanUterusSpleenHerpesvirus 1 HumanBiologymedicine.disease_causeVirus ReplicationHerpesviridaeVirusMiceVirologyChlorocebus aethiopsmedicineAnimalsHumansAntigens ViralVero CellsMedullaCerebral CortexMice Inbred BALB CAdrenal glandGeneral MedicineVirologymedicine.anatomical_structureHerpes simplex virusSpinal CordAdrenal MedullaVaginaVaginaFemaleArchives of virology
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