Search results for "Memory."
showing 10 items of 1949 documents
Programa de revisión de vida apoyado en las nuevas tecnologías para las personas mayores: Una aplicación de tecnologías positivas
2010
Existe una importante prevalencia de sintomatología depresiva en la población de la tercera edad. Sin embargo, pocas personas mayores reciben tratamiento adecuados para este tipo de dolencias. Entre las opciones terapéuticas disponibles figura la técnica de Revisión de Vida (RV). El objetivo de este artículo es presentar un programa de terapia para personas mayores basado en la técnica de Revisión de Vida a través de las nuevas tecnologías. El programa terapéutico se encuentra implantado en una plataforma tecnológica de e-salud (Sistema Mayordomo) y se enfoca en el entrenamiento de la recuperación de recuerdos autobiográficos específicos positivos. La herramienta tecnológica se dirige a enr…
A material for memory
2022
Every piece of architecture always aspires to become a monument, if only for the intentionality of meaning, witness and duration that becomes suggestive and evident through the etymological interpretation of the Latin verbs memini, moneo, maneo: every construction, in fact, it recalls the sense of its necessity and essence; it admonishes by arousing respect with the force of the image and the meaning it conveys; it remains durable and, ideally, eternal. There are, then, the architectures specially built to remember in which the utilitas transcends the usual considerations of functional type and sublimates itself in the manifestation of the memory, while the fi rmitas conserves and maintains…
El ritmo de la sociabilidad festiva en las rallas de Valencia
2018
This paper is concemed with the experience of time in the Festival of the Fallas of Valencia. It attributes a central role to the concept of festive sociability. The first section summarises basic concepts. A second part describes the Festival. The third section deals with the community's collective memory and its cyclic sense of history. The fourth describes the annual cycle of the permanent festive sociability of the Falla. A fifth section is concemed with the intensification of the rhythm of festive sociability during the Festive Event; it produces a reorganisation of time and space which go along with other relevant changes at the personal and community levéis. The participants have an …
Subtle Increases in Interletter Spacing Facilitate the Encoding of Words during Normal Reading
2012
BackgroundSeveral recent studies have revealed that words presented with a small increase in interletter spacing are identified faster than words presented with the default interletter spacing (i.e., w a t e r faster than water). Modeling work has shown that this advantage occurs at an early encoding level. Given the implications of this finding for the ease of reading in the new digital era, here we examined whether the beneficial effect of small increases in interletter spacing can be generalized to a normal reading situation.MethodologyWe conducted an experiment in which the participant's eyes were monitored when reading sentences varying in interletter spacing: i) sentences were present…
Spatial learning and expression patterns of PP1 mRNA in mouse hippocampus.
2009
<i>Background:</i> Synaptic plasticity is believed to be the major cellular basis for learning and memory. Protein phosphorylation is a key process involved in changes in the efficacy of neurotransmission. In long-term changes synaptic plasticity is followed by structural plasticity and protein de novo synthesis. Such mechanisms are believed to build the basis of hippocampal learning and memory investigated in the Morris water maze (MWM) task. To examine the role of dephosphorylation during that model for spatial learning, we analyzed protein phosphatase 1 (PP1) expression in the hippocampus of mice at various stages of the task and in two groups with different learning abilitie…
When the smile is a cue to familiarity
2000
International audience; The question discussed in the two following experiments concerns the effect of facial expressions on face recognition. Famous and unknown faces with neutral or smiling expression were presented for different inspection durations (15 ms vs 1000 ms). Subjects had to categorize these faces as famous or unknown (Experiment 1), or estimate their degree of familiarity on a rating scale (Experiment 2). Results showed that the smile increased ratings of familiarity for unfamiliar faces (Experiments 1 and 2) and for famous faces (Experiment 2). These data are discussed in the framework of current face-recognition models and are interpreted in terms of social value of the smil…
Study time effects in recognition memory.
2004
We empirically tested the assumption that study time increases recognition accuracy because the storage of information is better when study time is longer as Shiffrin and colleagues have reported, an assumption common to parallel models of recognition. In the present study with 123 subjects, we examined the effect of item strength on four measures: hit rate, false alarm rate, d′, and β, for a single-word recognition task with longer study times than those usually used in the literature. Analysis indicated significant increase for hit rate and d′ and a decrease in false alarm rate, as one goes from weak to stronger study conditions, and a change in ln(β) when study time is greater than 1 se…
Transcutaneous immunization with imiquimod is amplified by CD40 ligation and results in sustained cytotoxic T-lymphocyte activation and tumor protect…
1999
Transcutaneous immunization (TCI) using ligands of Toll-like receptors (TLRs) and cytotoxic T-lymphocyte (CTL) epitopes lead to the induction of potent T-cell responses. To characterize the efficacy of TCI-mediated CTL activation, we monitored the frequency and functional activity of specific CTL induced with TCI using the ovalbumin-derived epitope SIINFEKL composed in creme containing the synthetic TLR7 ligand R-837. We found that the frequency and activity decayed rapidly 10 d post-TCI. Consistently, no significant memory T-cell formation was detectable. In a prophylactic vaccination setting, TCI was protective against a lethal challenge with ovalbumin expressing EG.7 thymoma cells when t…
Pharmacological approaches in bipolar disorders and the impact on cognition: a critical overview
2012
Dias VV, Balanza-Martinez V, Soeiro-de-Souza MG, Moreno RA, Figueira ML, Machado-Vieira R, Vieta E. Pharmacological approaches in bipolar disorders and the impact on cognition: a critical overview. Objective: Historically, pharmacological treatments for bipolar disorders (BD) have been associated with neurocognitive side-effects. We reviewed studies which assessed the impact of several psychopharmacological drugs on the neurocognitive function of BD patients. Method: The PubMed database was searched for studies published between January 1980 and February 2011, using the following terms: bipolar, bipolar disorder, mania, manic episode, or bipolar depression, cross-referenced with cognitive…
Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation
2020
AbstractThe interphase nucleus is functionally organized in active and repressed territories defining the transcriptional status of the cell. However, it remains poorly understood how the nuclear architecture of neurons adapts in response to behaviorally relevant stimuli that trigger fast alterations in gene expression patterns. Imaging of fluorescently tagged nucleosomes revealed that pharmacological manipulation of neuronal activity in vitro and auditory cued fear conditioning in vivo induce nucleus-scale restructuring of chromatin within minutes. Furthermore, the acquisition of auditory fear memory is impaired after infusion of a drug into auditory cortex which blocks chromatin reorganiz…