Search results for "Memory"
showing 10 items of 2004 documents
A dominant gene for developmental dyslexia on chromosome 3.
2001
Developmental dyslexia is a neurofunctional disorder characterised by an unexpected difficulty in learning to read and write despite adequate intelligence, motivation, and education. Previous studies have suggested mostly quantitative susceptibility loci for dyslexia on chromosomes 1, 2, 6, and 15, but no genes have been identified yet. We studied a large pedigree, ascertained from 140 families considered, segregating pronounced dyslexia in an autosomal dominant fashion. Affected status and the subtype of dyslexia were determined by neuropsychological tests. A genome scan with 320 markers showed a novel dominant locus linked to dyslexia in the pericentromeric region of chromosome 3 with a m…
Maternal history of reading difficulty is associated with reduced language-related gray matter in beginning readers.
2012
Family history and poor preliteracy skills (referred to here as familial and behavioral risk, respectively) are critical predictors of developmental dyslexia. This study systematically investigated the independent contribution of familial and behavioral risks on brain structures, which had not been explored in past studies. We also examined the differential effects of maternal versus paternal history on brain morphometry, and familial risk dimensionally versus categorically, which were also novel aspects of the study. We assessed 51 children (5 to 6 years of age) with varying degrees of familial and behavioral risks for developmental dyslexia and examined associations with brain morphometry…
Familial dyslexia: neurocognitive and genetic correlation in a large Finnish family.
2007
Neuropsychological findings of individuals with dyslexia (n=24) from a large, three-generation Finnish family are presented. We have previously performed whole genome linkage scanning in this family and found that dyslexia in this kindred segregates with a single locus in the pericentromeric area of chromosome 3. Those included in the analyses were carefully evaluated for general cognitive ability, reading and spelling skills, and reading-related neurocognitive skills. The neurocognitive type of dyslexia segregating in this family consisted of deficits in phonological awareness, verbal short-term memory, and rapid naming. Severe dyslexia also seemed to be connected with a general language d…
Influence of articulation rate on two memory tasks in young and older adults.
2008
This study investigated the relation between phonological loop functioning and age. Phonological loop is a time-based subsystem of the Working Memory Model of Baddeley and Wilson, which uses rehearsal of information as an active process to avoid phonological decay. Performance differences were examined between young and older adults in two speech-based memory tasks, such as the immediate serial recall of words and the Digit Ordering Task. Analysis showed that performance on both tasks was lower for the older group. Articulation rate was also measured to test the hypothesis that the impairment of some cognitive functions in adults can be associated to their slowness or the greater time need…
The role of novelty detection in food memory
2010
International audience; Memory plays a central role in food choice. Recent studies focusing on food memory in everyday eating and drinking behaviour used a paradigm based on incidental learning of target foods and unexpected memory testing, demanding recognition of the target among distractors, which deviate slightly from the target. Results question the traditional view of memory as reactivation of previous experiences. Comparison of data from several experiments shows that in incidentally learned memory, distractors are rejected, while original targets are not recognised better than by chance guessing. Food memory is tuned at detecting novelty and change, rather than at recognising a prev…
Individual differences in working memory capacity are unrelated to the magnitudes of retrocue benefits
2021
AbstractPrevious studies have associated visual working memory (VWM) capacity with the use of internal attention. Retrocues, which direct internal attention to a particular object or feature dimension, can improve VWM performance (i.e., retrocue benefit, RCB). However, so far, no study has investigated the relationship between VWM capacity and the magnitudes of RCBs obtained from object-based and dimension-based retrocues. The present study explored individual differences in the magnitudes of object- and dimension-based RCBs and their relationships with VWM capacity. Participants completed a VWM capacity measurement, an object-based cue task, and a dimension-based cue task. We confirmed tha…
Effect of focal cerebellar lesions on procedural learning in the serial reaction time task
1998
Prior studies have shown that procedural learning is severely impaired in patients with diffuse cerebellar damage (cortical degeneration) as measured by the serial reaction time task (SRTT). We hypothesize that focal cerebellar lesions can also have lateralized effects on procedural learning. Our objective was to assess the effects of focal cerebellar lesions in procedural learning as measured by the SRTT. We studied 14 patients with single, unilateral vascular lesions in the territory of the posterior-inferior or superior cerebellar artery, who were compared with ten age- and sex-matched controls in a one-handed version of the SRTT. Patients with lesions at any other level of the brain or …
Psychophysiological and vocal measures in the detection of guilty knowledge.
2004
The Guilty Knowledge Test (GKT) and its variant, the Guilty Actions Test (GAT), are both psychophysiological questioning techniques aiming to detect guilty knowledge of suspects or witnesses in criminal and forensic cases. Using a GAT, this study examined the validity of various physiological and vocal measures for the identification of guilty and innocent participants in a mock crime paradigm. Electrodermal, respiratory, and cardiovascular measures successfully differentiated between the two groups. A logistic regression model based on these variables achieved hit rates of above 90%. In contrast to these results, the vocal measures provided by the computerized voice stress analysis system …
Intraoperative brain mapping of language, cognitive functions, and social cognition in awake surgery of low-grade gliomas located in the right non-do…
2020
Abstract Objective The aim of our study was to evaluate the usefulness of cortical-subcortical intraoperative brain mapping (ioBM) in resective awake surgery of low-grade gliomas (LGG) of the right non-dominant hemisphere (RndH). It was estimated how ioBM may affect both the extent of resection and postoperative outcome of language, spatial cognition, social cognition, and executive functions including attention and working memory. Patients and Methods : Fifteen patients that underwent ioBM in resective awake surgery of LGG located on the RndH, were included. A cohort of 15 patients with the same tumour location operated under general anaesthesia without brain mapping was used as control. S…
The relations between social anxiety and social intelligence: A latent variable analysis
2011
Social anxiety has been associated with biases in cognitive processing and deficits in social performances. Yet, it remains unclear if these variations may be partly attributable to deficits in fundamental social abilities: for example, social intelligence (SI). Using the Magdeburg Test of Social Intelligence (MTSI) as an objective and performance based SI measure, we examined the relationship between social anxiety and SI in a general population sample (N=110) using Structural Equation Modeling. Dimensions of social anxiety as postulated by Clark and Wells (1995) and facets of SI (social understanding, social memory, and social perception), were negatively correlated. Use of safety-behavio…