Search results for "Menispermaceae"

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Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira

2003

From the aerial parts of Cissampelos pareira L. (Menispermaceae), a chalcone-flavone dimer has been isolated which, mainly from NMR spectroscopic and MS data, was proved to be 2-(4-hydroxy-3-methoxyphenyl)-7-(4-methoxyphenyl)-6-(2-hydroxy-4,6-dimethoxybenzoyl)-furano[3,2-g]benzopyran-4-one. This has been assigned the trivial name cissampeloflavone. The compound has good activity against Trypanosoma cruzi and T. brucei rhodesiense and has a low toxicity to the human KB cell line.

ChalconeMagnetic Resonance Spectroscopymedicine.drug_classStereochemistryDimerAntiprotozoal AgentsPlant ScienceHorticultureBiologyPharmacognosyBiochemistryFlavonesKB Cellschemistry.chemical_compoundChalconemedicineAnimalsHumansMenispermaceaeTrypanosoma cruziMolecular BiologyFlavonoidschemistry.chemical_classificationEukaryotaGeneral MedicineCissampelosPlant Components Aerialbiology.organism_classificationAntineoplastic Agents PhytogenicchemistryCissampelos pareiraAntiprotozoalDimerizationPhytochemistry
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