Search results for "Merkel"
showing 10 items of 45 documents
First International Merkel Cell Symposium, Heidelberg, Germany
1995
Brief an Johann G. Herder.
1799
Ms. 930a, Nr. 17, Bl. 43r-44v Garlieb H. Merkel. Brief an Johann G. Herder. Berlin, d[en] 9ten März 1799 Autora rokraksts / Autograph, vācuval. / Deutsch [4] lpp. / S. Attēlu numuri / Bildnummern: 930a-017-1, 930a-017-2-3, 930a-017-4 Wahrscheinlich handelt es sich bei diesem Dokument um ein Konzeptdes Briefes von Merkel an Herder; es ist also nicht gesichert, ob dieser in Reinschrift verfasst undan den Adressaten abgeschickt wurde. Merkel schreibt sehr persönlich über sich selbst und versucht das Bild eines draufgängerischen Lebemannes zu geben, der seinen Horizont, wenn möglich, lieber durch eigene Erfahrungen als durch Buchlektüre erweitern will. Merkel weiß, dass er diese Sichtweise mit …
Distribution and coexistence of chromogranin A-, serotonin-and pancreastatin-like immunoreactivity in endocrine-like cells of the human anal canal
1992
The comparative distribution and coexistence of chromogranin A (CGA)-, serotonin (5-hydroxytryptamine; 5-HT)- and pancreastatin (PST)-like immunoreactivity in endocrine-like cells of the human anal canal was investigated by light-microscopic immunocytochemistry. The largest population of colorectal endocrine-like cells consisted of CGA-immunoreactive (ir) cells, followed by the 5-HT-ir and PST-ir cell population. In the anal transitional zone (ATZ), CGA- and 5-HT-immunoreactivity was equally distributed; ir-PST was confined to a smaller endocrine-like cell population. In the squamous zone and the perianal skin, Merkel cells in the basal layer of the epidermis and hair follicles exhibited ir…
La Europa social / 1. El modelo europeo de sociedad
2005
Brief an Garlieb H. Merkel
1798
Ms. 930a, Nr. 13, Bl. 35r-[36v] August Hennings. Brief an Garlieb H. Merkel, Ploen, den 20. Dece[mber] 1798 Autora rokraksts / Autograph, vācu val. / Deutsch [3] lpp. / S. Attēlu numuri / Bildnummern: 930a-013-1, 930a-013-2, 930a-013-3 Hennings, der dänische Amtmann in Plön und Bekannte des dänischen Ministers Schimmelmann, schreibt in seiner Funktion als Herausgeber der Zeitschrift „Genius der Zeit“ an Merkel. Er kündigt an, einen Aufsatz zu drucken, in dem Merkel Partei für seinen Schriftstellerkollegen Johann(es) Falk ergreift, worum ihn dieser in einem anderen Brief gebeten hat (vgl. Ms. 930a-012). Merkels Aufsatz soll in der Februarausgabe 1799 erscheinen. Der Aufsatz sowie der hier üb…
Atklāj Merķeli sevī!
2019
Electron microscopic immunogold cytochemistry reveals chromogranin A confined to secretory granules of porcine Merkel cells
1990
By ultrastructural immunohistochemistry using the immunogold technique, immunoreactive (ir) Chromogranin A (CGA) was found to be confined to the secretory vesicles of porcine Merkel cells. CGA was present predominantly in the periphery of the electron-dense core and on the clear halo. These findings indicate that CGA is a regular constituent of Merkel cell secretory granules but probably not exclusively responsible for their electron opacity.
Chromogranin A in the Mammalian Merkel Cell: Cellular and Subcellular Distribution
1989
Chromogranin-A (CGA), which accounts for more than half the soluble matrix protein in secretory granules of various neuroendocrine cells, has a wide spectrum of potential biological roles and is considered an important marker of the diffuse neuroendocrine system (DNES). Light and electron microscopic immunohistochemistry of mammalian skin revealed that Merkel cells are exclusively CGA-immunoreactive (ir) and that the immunoreaction is localized in the secretory granules. This finding supports the classification of the Merkel cell as a member of the DNES. The CGA immunoreactivity was restricted to Merkel cells of pigs and humans. In human embryonic skin, CGA was expressed in Merkel cells as …
Chapter 20 Multiple messenger candidates and marker substances in the mammalian Merkel cell – axon complex: a light and electron microscopic immunohi…
1988
Publisher Summary This chapter discusses multiple messenger candidates and marker substances in the mammalian merkel cell—axon complex. According to the APUD theory, cells of the diffuse neuroendocrine system (DNES) are essentially characterized by containing amines, peptides and marker substances like neuronspecific enolase (NSE) and chromogranin A (CGA). By the comparison of the histotopography of immunostained peptides, CGA and neuroendocrine markers, there was an expectation to find out the most appropriate immunohistochemical marker of the Merkel cell and to get further insight into the complex chemo-anatomy and possible functional spectrum of the Merkel cell -axon complex at various d…