Search results for "Mesh"

NOVEL TOOLS FOR THE MECHANICAL ANALYSIS OF THIN PLATES AND RELEVANCE ON MEMBRANE-BASED TECHNOLOGIES

2020

A backward sweep method for power flow solution in distribution networks

2010

Abstract A methodology for the analysis of radial or weakly meshed distribution systems supplying voltage dependent loads is here developed. The solution process is iterative and, at each step, loads are simulated by means of impedances. Therefore, at each iteration, it is necessary to solve a network made up only of impedances; for this kind of network, all the voltages and currents can be expressed as linear functions of a single unknown current (in radial systems) or of two unknown currents for each independent mesh (for meshed systems). The methodology has been called “backward” since the unique equation, in case of radial network, and the linear system of equations, in case of meshed n…

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

2015

International audience; Here we describe a spontaneous mutation in the Zdhhc13 (zinc finger, DHHC domain containing 13) gene (also called Hip14l), one of 24 genes encoding palmitoyl acyltransferase (PAT) enzymes in the mouse. This mutation (Zdhhc13luc) was identified as a nonsense base substitution, which results in a premature stop codon that generates a truncated form of the ZDHHC13 protein, representing a potential loss-of-function allele. Homozygous Zdhhc13luc/Zdhhc13luc mice developed generalized hypotrichosis, associated with abnormal hair cycle, epidermal and sebaceous gland hyperplasia, hyperkeratosis, and increased epidermal thickness. Increased keratinocyte proliferation and accel…

Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

2021

Abstract Background The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted the surgical community. Recommendations have been published to manage patients needing surgery during the COVID-19 pandemic. This survey, under the aegis of the Italian Society of Endoscopic Surgery, aims to analyze how Italian surgeons have changed their practice during the pandemic. Methods The authors designed an online survey that was circulated for completion to the Italian departments of general surgery registered in the Italian Ministry of Health database in December 2020. Questions were divided into three sections: hospital organization, screening policies, and safety profile of…

Integrazione di tecniche topografiche tradizionali ed innovative per analisi 3D ed il monitoraggio di superfici rocciose

2008

Le tecniche di rilievo topografico sono utilizzate da sempre per il monitoraggio di superfici rocciose per ottenere indicazioni sui micromovimenti degli stessi ammassi. Le esperienze recentemente maturate in ambito geologico-applicativo hanno mostrato le potenzialità della tecnica laser scanning long range come ausilio nel rilievo delle superfici rocciose per la possibilità di acquisire un’elevata quantità di dati con rapidità, ma con il limite di una accuratezza non inferiore al centimetro. Attraverso tale tecnica si possono indagare le principali caratteristiche geomorfologiche e geometriche dell’oggetto naturale ed eventualmente quantificare le variazioni geometriche occorse nel tempo. I…

Differential influence of Pomphorhynchus laevis (Acanthocephala) on brain serotonergic activity in two congeneric host species.

2007

The physiological mechanisms by which parasites with complex life cycles manipulate the behaviour of their intermediate hosts are still poorly understood. In Burgundy, eastern France, the acanthocephalan parasitePomphorhynchus laevisinverses reaction to light in its amphipod hostGammarus pulex, but not inGammarus roeseli, a recent invasive species. Here, we show that this difference in manipulation actually reflects a difference in the ability of the parasite to alter brain serotonergic (5-HT) activity of the two host species. Injection of 5-HT in uninfected individuals of both host species was sufficient to inverse reaction to light. However, a difference in brain 5-HT immunocytochemical s…

Development of a low-cost IoT system to detect and locate lightning strikes

2020

Lightnings are violent natural phenomena and can generate many expenditures, specially when they strike in urban areas. The identification of the concrete geographic area where they strike is of critical importance for emergency services in order to enhance their effectiveness by doing an intensive coverage of the affected area. To achieve this aim, this paper proposes a design, prototype and validation of a distributed network of Internet of Things (IoT) devices to enable detection and location of lightning strikes. The IoT devices are empowered with lightning detection capabilities and are synchronized with the other devices in the sensor network. All of them cooperate within a network th…

Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis

2014

International audience; Adipose tissue fibrosis development blocks adipocyte hypertrophy and favors ectopic lipid accumulation. Here, we show that adipose tissue fibrosis is associated with obesity and insulin resistance in humans and mice. Kinetic studies in C3H mice fed a high-fat diet show activation of macrophages and progression of fibrosis along with adipocyte metabolic dysfunction and death. Adipose tissue fibrosis is attenuated by macrophage depletion. Impairment of Toll-like receptor 4 signaling protects mice from obesity-induced fibrosis. The presence of a functional Toll-like receptor 4 on adipose tissue hematopoietic cells is necessary for the initiation of adipose tissue fibros…

Spike-in SILAC proteomic approach reveals the vitronectin as an early molecular signature of liver fibrosis in hepatitis C infections with hepatic ir…

2014

Hepatitis C virus (HCV)-induced iron overload has been shown to promote liver fibrosis, steatosis, and hepatocellular carcinoma. The zonal-restricted histological distribution of pathological iron deposits has hampered the attempt to perform large-scale in vivo molecular investigations on the comorbidity between iron and HCV. Diagnostic and prognostic markers are not yet available to assess iron overload-induced liver fibrogenesis and progression in HCV infections. Here, by means of Spike-in SILAC proteomic approach, we first unveiled a specific membrane protein expression signature of HCV cell cultures in the presence of iron overload. Computational analysis of proteomic dataset highlighte…

Anterior/Apical single incision mesh (Elevate™): Surgical experience, anatomical and functional results, and long-term complications

2021

Abstract Objective Pelvic organ prolapse is a common condition among post-menopausal women, and surgery is often the standard treatment proposed. Native tissue vaginal surgery is burdened by a high rate of recurrence, and mesh vaginal surgery has become current practice. The purpose of this study was to evaluate the safety and the effectiveness of the vaginal kit Anterior/Apical single incision mesh Elevate™ for the correction of anterior and apical compartment prolapse. Study design Data of patients with symptomatic anterior vaginal prolapse stage ≥ II, receiving mesh repair with the Anterior/Apical Elevate single incision system between January 2010 and January 2015 were retrieved. Prolap…