Search results for "Meta-"

Deguna obstrukcijas klīniskā klasifikācija ar 4-fāzu rinomanometriju

2015

Rinomanometrija joprojām var tikt uzskatīta par standartu objektīvai deguna elpošanas funkcijas mērīšanai. Spiediena un plūsmas attiecības x-y-attēlojumā parāda tipiskas cilpas, kas apstiprina nepieciešamību elpošanu novērtēt pēc 4 fāzēm; tas pamato četru fāzu rinomanometrijas būtību. 3 pamatnostādnes 4PR ir: aizvietot novērojumus ar mērījumiem, jaunu parametru ieviešana, kas ir saistīti ar subjektīvo deguna obstrukcijas sajūtu, un grafiska informācija par traucētu deguna vārsta funkciju. Šeit aprakstītā klīnisko datu meta-analīze ir nepieciešama, lai apstiprinātu, ka 4-fāzu rinomanometrija sniedz vairāk, kā arī svarīgāku klīnisko informāciju, salīdzinot ar tā saukto „klasisko” rinomanometr…

Safety Evaluation of α-Lipoic Acid Supplementation: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Studies

2020

Alpha-lipoic acid (ALA) is a natural short-chain fatty acid that has attracted great attention in recent years as an antioxidant molecule. However, some concerns have been recently raised regarding its safety profile. To address the issue, we aimed to assess ALA safety profile through a systematic review of the literature and a meta-analysis of the available randomized placebo-controlled clinical studies. The literature search included EMBASE, PubMed Medline, SCOPUS, Google Scholar, and ISI Web of Science by Clarivate databases up to 15th August 2020. Data were pooled from 71 clinical studies, comprising 155 treatment arms, which included 4749 subjects with 2558 subjects treated with ALA an…

Epidemiological and molecular associations between central nervous system disorders and cancer

2021

The study of comorbidity is becoming a key topic in biomedical research, which is especially relevant in the context of population ageing. Comorbidity has profound implications for individuals, practitioners, and health care systems. As a consequence, increasing efforts are being made by the scientific community to characterize better how disorders relate to each other and to identify the factors producing these associations. Cancer and central nervous system (CNS) disorders are among the top leading causes of death and disease burden worldwide. In recent decades direct and inverse patterns of association between CNS disorders and cancer have been reported. However, observational studies ha…

Cardiovascular and Renal Outcomes of Renin–Angiotensin System Blockade in Adult Patients with Diabetes Mellitus: A Systematic Review with Network Met…

2016

Background Medications aimed at inhibiting the renin–angiotensin system (RAS) have been used extensively for preventing cardiovascular and renal complications in patients with diabetes, but data that compare their clinical effectiveness are limited. We aimed to compare the effects of classes of RAS blockers on cardiovascular and renal outcomes in adults with diabetes. Methods and Findings Eligible trials were identified by electronic searches in PubMed/MEDLINE and the Cochrane Database of Systematic Reviews (1 January 2004 to 17 July 2014). Interventions of interest were angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and direct renin (DR) inhibitors. T…

Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and me…

2017

PubMed: 28779882

Calibration of microscopic traffic simulation models for evaluating operation and safety performance at roundabouts

Adsorption Properties of Nax and Bax Zeolites: Correlation between Structural and Thermodynamic Results on Para- and Meta-xylene Adsorption

1996

A comparison is made between NaX and BaX adsorption properties starting from crystallographic data and thermodynamic measurements. Adsorption isotherms and differential adsorption heats of pure para- and meta-xylenes in NaX and BaX zeolites are interpreted in the light of crystallographic results.

Alcohol consumption and risk of uterine myoma: A systematic review and meta analysis

2017

Background The published data about alcohol consumption and uterine myoma are scanty and controversial: some studies found positive association whereas other studies showed no association. Objectives To conduct a systematic review and meta-analysis to determine whether alcohol is a risk factor for myoma. Search strategy A MEDLINE/EMBASE search was carried out, supplemented by manual searches of bibliographies of the selected studies. Selection criteria Articles published as full-length papers in English. In the review we included all identified studies. Otherwise, the inclusion criteria for studies included in the meta-analysis were: a) case-control or cohort studies, reporting original dat…

Intervenciones individuales para mejorar la adherencia al tratamiento farmacéutico, la dieta y la actividad física en adultos con hipertensión primar…

2020

Introduction Hypertension is a chronic disease with 31% worldwide prevalence in adults. It has been associated with non-adherence to therapeutic regime with a negative impact on the prognosis of the disease and healthcare-associated costs. So, it is necessary to identify effective interventions to improve adherence among the afflicted population. The objective of this protocol is to describe the methods for a systematic review that will evaluate the effect of individual interventions so as to improve adherence to the prescribed pharmacological treatment, as well as to prescribed diet and physical activity in adults with primary hypertension. Methods and analysis A systematic search of studi…

Theoretical adequacy, methodological quality and efficacy of online interventions targeting resilience: a systematic review and meta-analysis

2021

Abstract Background There is a growing interest in the promotion of mental health, and concepts as resilience are re-emerging and taking relevance. In addition, Information and Communication Technologies can provide potential benefits in the field of mental health, and the treatment of mental disorders in particular. This study aims to synthesize the evidence of internet-based resilience interventions, analyzing the theoretical adequacy, methodological quality and efficacy. Methods A systematic search was performed. The eligibility criteria stated for this article were: randomized controlled trials targeted at adults or adolescents and including any psychological intervention focussing on r…