Search results for "Meta-"

showing 10 items of 1069 documents

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

2013

Author version made available in accordance with the publisher's policy.

Candidate geneRefractive errorBone Morphogenetic Protein 2Genome-wide association studyVARIANTSGenomeGenome-wide association studies0302 clinical medicineRisk FactorsMyopiaGRIA4Genetics0303 health sciencesKCNQ Potassium ChannelsDisease geneticsEYE GROWTHASSOCIATIONRETINAL-PIGMENT EPITHELIUMRefractive ErrorsGenetic load3. Good healthADAPTED MOUSE RETINAMeta-analysisACIDPOTASSIUM CHANNELEXPRESSIONSingle-nucleotide polymorphismBiologyWhite PeopleArticle03 medical and health sciencesAsian PeoplemedicineGeneticsHumansGenetic Predisposition to DiseaseReceptors AMPAgene; myopia; refractive030304 developmental biologyHomeodomain Proteinsta1184ta3121medicine.diseaseGENEAlcohol OxidoreductasesSERINE-PROTEASEbiology.protein030221 ophthalmology & optometrySusceptibility locusTrans-ActivatorsEye disorderLamininSerine ProteasesGWAS; meta-analyses; refractive error; myopiaGenome-Wide Association StudyNature Genetics
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Physical activity and risk of atrial fibrillation in the general population : meta-analysis of 23 cohort studies involving about 2 million participan…

2021

Regular physical activity is well established to be associated with reduced risk of cardiovascular disease outcomes. Whether physical activity is associated with the future risk of atrial fibrillation (AF) remains a controversy. Using a systematic review and meta-analysis of published observational cohort studies in general populations with at least one-year of follow-up, we aimed to evaluate the association between regular physical activity and the risk of AF. Relevant studies were sought from inception until October 2020 in MEDLINE, Embase, Web of Science, and manual search of relevant articles. Extracted relative risks (RRs) with 95% confidence intervals (CIs) for the maximum versus the …

Cardiac arrhythmiasMalerytmihäiriötEpidemiologyphysical activity030204 cardiovascular system & hematology0302 clinical medicinesystematic reviewRisk FactorsEpidemiologyMedicineatrial fibrillation030212 general & internal medicinekohorttitutkimussystemaattiset kirjallisuuskatsaukseteducation.field_of_studymeta-analyysiriskitekijäteteisvärinäObservational Studies as Topicrisk factorcardiac arrhythmiasMeta-analysisFemaleCohort studyfyysinen aktiivisuusCohort studymedicine.medical_specialtyPopulationMotor ActivityRisk Assessment03 medical and health sciencesInternal medicinecohort studyHumansRisk factoreducationExercisePhysical activitybusiness.industryArrhythmias CardiacAtrial fibrillationConfidence intervalmeta-analysisRelative riskSystematic reviewObservational studyRisk factorbusinessMeta-Analysis
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Effects of sauna bath on heart failure : A systematic review and meta-analysis

2018

Background: Sauna bath has potential as a lifestyle treatment modality for heart failure (HF). It is important to analyze the current evidence to help suggest paths of future study and potential for clinical application. Hypothesis: Sauna bath has a positive effect on HF patients. Methods: PubMed, Cochrane Library, and CINAHL databases were searched to identify randomized and nonrandomized controlled studies to compare effects of sauna bath with no sauna bath. Studies were searched for both infrared sauna bath and Finnish sauna bath. The strength of evidence was rated using a modified GRADE approach. Out of 1444 studies, nine met the inclusion criteria and were included in this review. Seve…

Cardiac function curveMalemedicine.medical_specialtyInfrared Rayssaunominenheart failureReview030204 cardiovascular system & hematologyCochrane Librarysydämen vajaatoimintaVentricular Function LeftSteam Bath03 medical and health sciences0302 clinical medicineInternal medicineWaon therapyterveysvaikutuksetNatriuretic Peptide BrainmedicineInfrared saunaHumansCardiac and Cardiovascular Systems030212 general & internal medicineAgedHeart FailureEjection fractionKardiologiWaon therapybusiness.industrymeta-analyysiStroke VolumeGeneral Medicinearchitecture.styleRecovery of FunctionMiddle Agedmedicine.diseaseBlood pressureTreatment OutcomearchitectureHeart failureFinnish SaunaCardiologysydän- ja verisuonitauditsauna bathFemaleCardiology and Cardiovascular MedicinebusinessBiomarkers
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Meta-analysis of the correlation between serum uric acid level and carotid intima-media thickness

2021

Objective Recently, increasing epidemiological evidence has shown that there is a correlation between serum uric acid level (SUA) and carotid intima-media thickness (CIMT). This paper explored the relationship between them through meta-analysis. Methods PubMed, Cochrane Library, EMBASE, Web of Science and Google Scholar were searched to obtain literature. The keywords used to retrieve the literature were carotid intima thickness, intima-media thickness, carotid atherosclerosis, carotid stenosis, carotid artery, uric acid, blood uric acid, and hyperuricaemia. The retrieval time was from the establishment of the database through July 2020. Stata15.0 and RevMan5.3 software were used for stati…

Carotid Artery DiseasesPublication EthicsType 2 diabetes030204 cardiovascular system & hematologyCardiovascular MedicineGastroenterologyVascular MedicineCarotid Intima-Media ThicknessGeographical Locationschemistry.chemical_compound0302 clinical medicineMathematical and Statistical TechniquesMedical ConditionsEndocrinologyMedicine and Health SciencesCarotid Stenosis030212 general & internal medicineResearch IntegrityMultidisciplinaryQStatisticsRMetaanalysisType 2 DiabetesChemistryCarotid ArteriesNeurologyCardiovascular DiseasesMeta-analysisPhysical Sciencescardiovascular systemMedicineResearch Articlemedicine.medical_specialtyChinaAsiaScience PolicyEndocrine DisordersScienceCerebrovascular DiseasesCardiologySubgroup analysisHyperuricemiaResearch and Analysis Methods03 medical and health sciencesInternal medicinemedicineDiabetes MellitusHumanscardiovascular diseasesStatistical Methodsbusiness.industryChemical CompoundsCardiovascular Disease Riskmedicine.diseaseAtherosclerosisConfidence intervalUric AcidIntima-media thicknesschemistryStrictly standardized mean differenceSample size determinationMetabolic DisordersPeople and PlacesUric acidbusinessAcidsMathematicsPLoS ONE
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Maternal cell phone use during pregnancy and child cognition at age 5 years in 3 birth cohorts

2018

Background: There have been few studies of children's cognitive development in relation to mothers' cell phone use, and most were limited to outcomes at age 3 years or younger. We examined the relationship between maternal cell phone use during pregnancy and cognitive performance in 5-year old children. Methods: This study included data from 3 birth cohorts: the Danish National Birth Cohort (DNBC) (n = 1209), Spanish Environment and Childhood Project (INMA) (n = 1383), and Korean Mothers and Children's Environment Health Study (MOCEH) (n = 497). All cohorts collected information about maternal cell phone use during pregnancy and cognitive performance in children at age 5. We performed linea…

Cell phonesIntelligenceMothersPooled analysisDanishCohort Studies03 medical and health sciences0302 clinical medicineChild DevelopmentCognitionPregnancyCognitive developmentMedicineHumans030212 general & internal medicineEffects of sleep deprivation on cognitive performanceChildChildrenlcsh:Environmental sciencesGeneral Environmental Sciencelcsh:GE1-350Pregnancybusiness.industryConfoundingCognitionmedicine.diseaselanguage.human_languageConfidence intervalCell Phone UseMeta-analysisPrenatal Exposure Delayed EffectsCohortlanguageFemalebusiness030217 neurology & neurosurgeryDemographyEnvironment International
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Molecular evidence for the inverse comorbidity between central nervous system disorders and cancers detected by transcriptomic meta-analyses.

2014

There is epidemiological evidence that patients with certain Central Nervous System (CNS) disorders have a lower than expected probability of developing some types of Cancer. We tested here the hypothesis that this inverse comorbidity is driven by molecular processes common to CNS disorders and Cancers, and that are deregulated in opposite directions. We conducted transcriptomic meta-analyses of three CNS disorders (Alzheimer's disease, Parkinson's disease and Schizophrenia) and three Cancer types (Lung, Prostate, Colorectal) previously described with inverse comorbidities. A significant overlap was observed between the genes upregulated in CNS disorders and downregulated in Cancers, as wel…

Central Nervous SystemCancer ResearchGene ExpressionDiseaseComorbidityBioinformaticsProstate cancer0302 clinical medicineNeoplasmsGenetics (clinical)0303 health sciencesWnt signaling pathwayParkinson DiseaseAlzheimer's diseasePeptidylprolyl Isomerase[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]3. Good health[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Alzheimer's diseaseResearch ArticleSignal Transductionlcsh:QH426-470[SDV.CAN]Life Sciences [q-bio]/CancerProtein degradationBiology03 medical and health sciencesAlzheimer Disease[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]medicineGeneticsCancer GeneticsHumansGene NetworksMolecular BiologyBiologyEcology Evolution Behavior and Systematics030304 developmental biologyPeptidylprolyl isomeraseGene Expression ProfilingCancerComputational Biologymedicine.diseaseColorectal cancerComorbidityMalariaNIMA-Interacting Peptidylprolyl IsomeraseMeta-analysislcsh:GeneticsGene Expression RegulationImmunologySchizophrenia[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie030217 neurology & neurosurgery
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The effects of lasers on bond strength to ceramic materials: A systematic review and meta-analysis

2018

Lasers have recently been introduced as an alternative means of conditioning dental ceramic surfaces in order to enhance their adhesive strength to cements and other materials. The present systematic review and meta-analysis aimed to review and quantitatively analyze the available literature in order to determine which bond protocols and laser types are the most effective. A search was conducted in the Pubmed, Embase and Scopus databases for papers published up to April 2017. PRISMA guidelines for systematic review and meta-analysis were followed. Fifty-two papers were eligible for inclusion in the review. Twenty-five studies were synthesized quantitatively. Lasers were found to increase bo…

CeramicsHigh variabilitylcsh:MedicineMaterials testinglaw.inventionAdhesion strength030207 dermatology & venereal diseasesMathematical and Statistical Techniques0302 clinical medicinelawMaterials TestingCeramicComposite materiallcsh:ScienceMultidisciplinaryBond strengthResearch AssessmentSystematic reviewOptical Equipmentvisual_artMeta-analysisPhysical SciencesCementsvisual_art.visual_art_mediumEngineering and TechnologyStatistics (Mathematics)Research ArticleMaterials scienceSystematic ReviewsMaterials by StructureAmorphous SolidsMaterials ScienceEquipmentResearch and Analysis MethodsDental Materials03 medical and health sciencesBindersStatistical MethodsMaterials by AttributeSurface TreatmentsLaserslcsh:R030206 dentistryLaserManufacturing ProcessesComposite Materialslcsh:QGlassMathematicsMeta-AnalysisPLOS ONE
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Influence of the chemical composition of monolithic zirconia on its optical and mechanical properties. Systematic review and meta-regression.

2021

Este artículo se encuentra disponible en la siguiente URL: https://www.jstage.jst.go.jp/article/jpr/66/2/66_JPR_D_20_00218/_pdf/-char/en Este artículo de investigación pertenece al número especial "Advances in Personalized Nursing Care". Purpose: This systematic review set out to investigate the influence of chemical composition and specimen thickness of monolithic zirconia on its optical and mechanical properties. Meta-analysis and meta-regression analyzed the effects of variations in percentages of yttrium, aluminum, and specimen thickness of monolithic zirconia. Study selection: The review followed recommendations put forward in the PRISMA checklist. An electronic search for relevant art…

CeramicsMaterials scienceWeb of scienceSurface Properties0206 medical engineeringDentistry02 engineering and technology03 medical and health sciencesDental Materials0302 clinical medicineMaterials TestingDentistry (miscellaneous)Meta-regressionCubic zirconiaYttriumCirconio - Propiedades mecánicas.Zirconium - Optical properties.business.industryMonolithic zirconia030206 dentistryCirconio - Propiedades ópticas.020601 biomedical engineeringZirconium - Mechanical properties.ZirconiumOral SurgerybusinessAluminumJournal of prosthodontic research
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Deoxynivalenol contamination in cereal-based foodstuffs from Spain: Systematic review and meta-analysis approach for exposure assessment

2022

Abstract The presence of deoxynivalenol (DON) has been repeatedly detected in cereal-based products collected from Spanish markets over the last years. Hence, the aim of this study was to conduct a systematic review and meta-analysis of the concentration and prevalence of DON in cereals and cereal-based products from Spanish markets intended for human consumption, in order to integrate the available data. Then, an exposure assessment was performed based on national consumption data. Results revealed a strong impact of DON in breakfast cereals (pooled concentration = 105.34 ng/g; pooled prevalence = 58%) and bread and derived products (pooled concentration = 95.17 ng/g; pooled prevalence = 6…

Cereal-basedTolerable daily intakebusiness.industrydigestive oral and skin physiologyfood and beveragesContaminationDeoxynivalenolFood safetyAge groupsMeta-analysisEnvironmental healthExposure assessmentSystematic reviewMedicineMeta-analysibusinessFood ScienceBiotechnologyExposure assessmentFood Control
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Effectiveness of Neural Mobilization Techniques in the Management of Musculoskeletal Neck Disorders with Nerve-Related Symptoms: A Systematic Review …

2021

Abstract Objective The objective was to assess the effectiveness of neural mobilization (NM) techniques in the management of musculoskeletal neck disorders with nerve-related symptoms (MND-NRS). Methods We conducted a systematic review with meta-analysis, using pain intensity, disability, perceived function, cervical range of motion, and mechanosensitivity as the main outcome measures. Results The systematic review included 22 studies (n = 978). More favorable outcomes were observed for NM on pain intensity compared with control interventions (standardized mean differences (SMDs) −0.92; 95% CI −1.66−0.18), but not compared with other treatments (OTs) (SMD 1.06; 95% CI −0.02 to 2.15). Regard…

Cervical range of motionmedicine.medical_specialtyNeck painNeck Painbusiness.industryOutcome measuresPsychological interventionNeck rotationGeneral MedicineIntensity (physics)Anesthesiology and Pain MedicineNeural mobilizationMeta-analysisPhysical therapymedicineHumansMusculoskeletal DiseasesNeurology (clinical)Range of Motion Articularmedicine.symptombusinessNeckPhysical Therapy ModalitiesPain Medicine
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