Search results for "Meta-"
showing 10 items of 1069 documents
Is Ethics Rational? Teleological, Deontological and Virtue Ethics Theories Reconciled in the Context of Traditional Economic Decision Making
2016
Abstract This article examines the most prominent ethical theories from the view point of economic rationality. Authors argue that utilitarian perspective which used to be connected with classical concepts of rationality in economics is not the only approach to understand reasoning behind the human behaviour. Moreover, Virtue ethics developed by Aristotle more than 2000 years ago, gives modern perspective to the questions of morale and ethics, connecting individuals to broader communities and explaining their motivation and actions. Similarly, deontological theories that from the first sight might seem as contradicting to rational choice, explain human behaviour when examined at the macro l…
Global collaborative networks on meta-analyses of randomized trials published in high impact factor medical journals: a social network analysis
2014
Abstract Background Research collaboration contributes to the advancement of knowledge by exploiting the results of scientific efforts more efficiently, but the global patterns of collaboration on meta-analysis are unknown. The purpose of this research was to describe and characterize the global collaborative patterns in meta-analyses of randomized trials published in high impact factor medical journals over the past three decades. Methods This was a cross-sectional, social network analysis. We searched PubMed for relevant meta-analyses of randomized trials published up to December 2012. We selected meta-analyses (including at least randomized trials as primary evidence source) published in…
Do-search -- a tool for causal inference and study design with multiple data sources
2020
Epidemiologic evidence is based on multiple data sources including clinical trials, cohort studies, surveys, registries, and expert opinions. Merging information from different sources opens up new possibilities for the estimation of causal effects. We show how causal effects can be identified and estimated by combining experiments and observations in real and realistic scenarios. As a new tool, we present do-search, a recently developed algorithmic approach that can determine the identifiability of a causal effect. The approach is based on do-calculus, and it can utilize data with nontrivial missing data and selection bias mechanisms. When the effect is identifiable, do-search outputs an i…
Causal Effect Identification from Multiple Incomplete Data Sources: A General Search-Based Approach
2021
Causal effect identification considers whether an interventional probability distribution can be uniquely determined without parametric assumptions from measured source distributions and structural knowledge on the generating system. While complete graphical criteria and procedures exist for many identification problems, there are still challenging but important extensions that have not been considered in the literature. To tackle these new settings, we present a search algorithm directly over the rules of do-calculus. Due to generality of do-calculus, the search is capable of taking more advanced data-generating mechanisms into account along with an arbitrary type of both observational and…
Early Response to treatment in Eating Disorders: A Systematic Review and a Diagnostic Test Accuracy Meta-Analysis
2016
Objective Early response to eating disorders treatment is thought to predict a later favourable outcome. A systematic review of the literature and meta-analyses examined the robustness of this concept. Method The criteria used across studies to define early response were summarised following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Diagnostic Test Accuracy methodology was used to estimate the size of the effect. Results Findings from 24 studies were synthesized and data from 14 studies were included in the meta-analysis. In Anorexia Nervosa, the odds ratio of early response predicting remission was 4.85(95%CI: 2.94–8.01) and the summary Area Under t…
1443Safety of red yeast rice supplementation: a systematic review and meta-analysis of randomized controlled trials
2019
Abstract Background Recently, concerns regarding the safety of red yeast rice (RYR) have been raised after the publication of some case reports claiming toxicity. Purpose Since the previous meta-analyses on the effects of RYR were mainly focused on its efficacy to improve the lipid profile and other cardiovascular parameters, we carried out a meta-analysis on safety data derived from the available randomized controlled clinical trials (RCTs). Methods Primary outcomes were musculoskeletal disorders (MuD). Secondary outcomes were non-musculoskeletal adverse events (Non-MuD) and serious adverse events (SAE). Subgroups analyses were carried out considering the intervention (RYR alone or in asso…
Hospitalisation and length of hospital stay following first-episode psychosis:Systematic review and meta-analysis of longitudinal studies
2019
AbstractBackgroundReducing hospitalisation and length of stay (LOS) in hospital following first episode psychosis (FEP) is important, yet reliable measures of these outcomes and their moderators are lacking. We conducted a systematic review and meta-analysis to investigate the proportion of FEP cases who were hospitalised after their first contact with services and the LOS in a hospital during follow-up.MethodsStudies were identified from a systematic search across major electronic databases from inception to October 2017. Random effects meta-analyses and meta-regression analyses were conducted.Results81 longitudinal studies encompassing data for 23 280 FEP patients with an average follow-u…
Deciphering transcriptional regulation mechanisms underlining fruit development and ripening in Vitis vinifera
2019
BACKGROUND: Grapes (Vitis vinifera ) are an important woody crop cultivated in a broad range of environmental conditions. Grapefruit development is a physiological process whose molecular regulatory networks are still not sufficiently investigated. OBJECTIVE: The primary aim of the work was to identify which key genes, molecular mechanisms and networks were involved in fruit ripening and development through a comparison of available transcriptomic data at different stages during grape development and ripening. Secondly, we aimed at identifying among these fruit-related genes, which genes play also a functional role in other developmental and physiological processes in reproductive tissues (…
‘You play like a Woman!’ Effects of gender stereotype threat on Women's performance in physical and sport activities: A meta-analysis
2018
Abstract Objectives The purpose of this quantitative review was to provide an estimation of the effect of stereotype threat on women's performance in sport. Design This review employed a meta-analytic technique. Method a meta-analysis with random effects model was performed on 24 effects. Publication bias was tested through funnel plots and Egger's regression test. Results Findings show a symmetric distribution of effects, making it possible to conclude that no file-drawer problem affected the collected sample of effects. Aggregating the results of the reviewed studies, a medium effect of stereotype threat manipulation on women's sport performances emerged (d = 0.33). Collected studies were…
An integrated fuzzy cells-classifier
2007
This paper introduces a genetic algorithm able to combine different classifiers based on different distance functions. The use of a genetic algorithm is motivated by the fact that the combination phase is based on the optimization of a vote strategy. The method has been applied to the classification of four types of biological cells, results show an improvement of the recognition rate using the genetic algorithm combination strategy compared with the recognition rate of each single classifier.