Search results for "Meta-analysis."
showing 10 items of 889 documents
The Impact of Venous Thromboembolism In Critically Ill Patients: A Meta-Analysis of Major Clinical outcomes
2010
Abstract Abstract 3327 Background: Critically ill patients are at high risk of developing venous thromboembolism (VTE) during their stay in the intensive care unit (ICU) because of premorbid medical and surgical conditions. The clinical consequences of Deep Vein Thrombosis (DVT) have the potential to be serious yet are frequently unrecognized in the Intensive Care Unit (ICU). In contrast to the extensive documentation on the short and long–term outcomes of patients with DVT evaluated in other clinical settings, little is known about the clinical course of this disease in the ICU setting. We hypothesized that both undetected and clinically evident VTE would affect the prognosis of critically…
Using meta-analytic path analysis to test theoretical predictions in health behavior: An illustration based on meta-analyses of the theory of planned…
2016
Abstract Objective Synthesizing research on social cognitive theories applied to health behavior is an important step in the development of an evidence base of psychological factors as targets for effective behavioral interventions. However, few meta-analyses of research on social cognitive theories in health contexts have conducted simultaneous tests of theoretically-stipulated pattern effects using path analysis. We argue that conducting path analyses of meta-analytic effects among constructs from social cognitive theories is important to test nomological validity, account for mediation effects, and evaluate unique effects of theory constructs independent of past behavior. We illustrate o…
Meta-Analysis, Ideals of Objectivity, and the Reliability of Medical Knowledge
2015
This paper focuses on the ideals of scientific objectivity as they emerge in discussions concerning meta-analyses and medical research. Stegenga (2011) has argued that meta-analyses fail to be objective because conducting them involves making judgments. I show that his reasoning is based on the so-called procedural ideal of objectivity, which can be questioned: this ideal is unattainable and does not capture some of the problematic issues of medical research. By introducing a case in research on selective serotonin reuptake inhibitors, I demonstrate why the so-called social view on objectivity succeeds better in accommodating 1) the way in which scientific research necessarily involves judg…
Efficacy of short-term psychotherapy for multiple medically unexplained physical symptoms: a meta-analysis.
2011
Multiple medically unexplained physical symptoms (MUPS) are considered to be difficult and costly to treat. The current meta-analysis therefore investigates the efficacy of short-term psychotherapy for MUPS. Based on a multiple-phase literature search, studies were selected according to a-priori defined inclusion criteria. The standardized mean gain was used as the effect size index. Separate data aggregation of between- and within-group contrasts was performed on the basis of a mixed effects model. Outcome variables were physical symptoms, disorder specific emotions, cognitions and behaviors, depressive symptoms, general psychopathology, functional impairment, and health care utilization. …
Using Sandelowski and Barroso's Meta-Synthesis Method in Advancing Qualitative Evidence.
2016
The purpose of this article was to iteratively account for and discuss the handling of methodological challenges in two qualitative research syntheses concerning patients’ experiences of hospital transition. We applied Sandelowski and Barroso’s guidelines for synthesizing qualitative research, and to our knowledge, this is the first time researchers discuss their methodological steps. In the process, we identified a need for prolonged discussions to determine mutual understandings of the methodology. We discussed how to identify the appropriate qualitative research literature and how to best conduct exhaustive literature searches on our target phenomena. Another finding concerned our statu…
Diagnostics for meta-analysis based on generalized linear mixed models
2012
Meta-analysis is the method to combine data coming from multiple studies, with the aim to provide an overall event-risk measure of interest summarizing information coming from the studies. In meta-analysis generalized linear mixed models (GLMM) are particularly used for a number of measures of interest since they allow the true effect size to differ from study to study while accepting binary, discrete as well as continuous response variable. In the present paper some strategies of influence diagnostics based on log-likelihood are suggested and discussed. These are considered for Individual Patient Data, Aggregate Data and their compounding.
The effectiveness of leadership: meta-analysis of trial, cross-sectional, and before after studies
2020
Abstract Background The clinical and surgical procedures are often based on scientifical evidence but 30-40% of patients do not receive treatment according to evidence based medicine. The main aim of this review and meta-analysis is to assess the effectiveness of leadership in healthcare setting. Methods It was conducted a literature research on MEDLINE, Pubmed and Scopus with publication year between 2015 and 2019. The inclusion criteria were studies involving healthcare workers that evaluated effectiveness of opinion leaders in improving behaviour of healthcare workers, according to clinical or patient related outcomes. The quality of studies were assesed with the NHLBI for before after s…
L'analyse statistique du profil sensoriel revisitée par une approche base de données
2015
During a sensory evaluation, trained subjects taste and score products on differentdescriptors in order to obtain a descriptive profile of these products. The data are thenanalyzed by several statistical methods (PCA, ANOVA…) in order to monitor the subjectperformances and map the product space.This work aims to revisit these statistical methods thanks to the analysis of a large number ofdatasets of sensory profiling data from the SensoBase (a database containing more than athousand of datasets). Different statistical methods of mapping and analysis ofperformances were compared, then improved. We mainly focused on the so-called scalingeffect (tendency of the subject to spread his scores mor…
Cardiovascular complications in COVID-19:A systematic review and meta-analysis
2020
Bloodstream Infections in Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis
2021
Background: Little is known about the occurrence of bloodstream infections in hospitalized patients with COVID-19 and the related clinical consequences. The aim of this systematic review and meta-analysis was to estimate the pooled occurrence of BSIs among hospitalized patients with COVID-19 and mortality of this patient population. Methods: A systematic search was performed on PubMed, EMBASE, and Web of Science from inception to 19 April 2021. The primary outcome was the occurrence of BSIs among hospitalized patients with COVID-19. The secondary outcome was mortality at the longest available follow-up. Results: Forty-six studies met the inclusion criteria, with a total of 42,694 patients e…