Search results for "Meta-analysis."
showing 10 items of 889 documents
Effects of Cognitive and Mental Health Factors on the Outcomes Following Carpal Tunnel Release: A Systematic Review and Meta-analysis.
2022
OBJECTIVE To determine the effects of the cognitive and mental health factors on the outcomes following carpal tunnel release (CTR). DATA SOURCES Embase, Pubmed/MEDLINE, Web of Science, CINAHL and Cochrane Central Register of Controlled Trials (CENTRAL) databases from inception to August 14, 2021. STUDY SELECTION Randomized controlled trials and observational studies of patients with CTR were included. The included studies aimed to determine the effect of the cognitive (catastrophic thinking, kinesiophobia and self-efficacy) or mental health factors (symptoms of anxiety and depression) on the outcomes at least three months post-CTR. DATA EXTRACTION Two independent reviewers performed data e…
Systemic therapies for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: a SCORTEN-based systematic review and meta-analysis.
2020
Background The SCORTEN score is a specific predictor of mortality for patients with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). There is little evidence in support of the common immunomodulating therapies for SJS/TEN. Objectives To systematically assess the effectiveness of several therapies for SJS/TEN through the SCORTEN score. Methods Databases were searched for original studies on the use of SCORTEN. Six meta-analyses were carried out on patients with SJS/TEN who received supportive care only or in combination with immunomodulating drugs: corticosteroids, cyclosporine, etanercept, immunoglobulins or a combination of corticosteroids with immunoglobulins. A multivaria…
Photobiomodulation and myofascial temporomandibular disorder: Systematic review and meta-analysis followed by cost-effectiveness analysis
2021
Background Photobiomodulation (PBM) is a non-invasive and non-pharmacological treatment, which, has shown beneficial results in the treatment of temporomandibular disorders (TMD) related pain. This systematic review and meta-analysis study aimed to evaluate the efficacy of photobiomodulation in the treatment of myofascial pain associated with (TMD by analyzing randomized clinical trials published from 2007 to February 2019. The secondary objective of the study was to perform a cost-effectiveness analysis of TMD treatment with photobiomodulation in patients with myofascial pain. Material and methods International databases were used: Pubmed, Medline and Web of Science; the initial search rai…
Which exercise prescriptions optimize V̇O2max during cancer treatment?—A systematic review and meta-analysis
2019
Author's accepted version (post-print). This is the peer reviewed version of the following article: Bjørke, A. C. H., Sweegers, M. G., Buffart, L. M., Raastad, T., Nygren, P. & Berntsen, S. (2019). Which exercise prescriptions optimize V̇O2max during cancer treatment? – A systematic review and meta‐analysis. Scandinavian Journal of Medicine & Science in Sports, 29(9), 1274-1287, which has been published in final form at https://doi.org/10.1111/sms.13442. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Available from 30/04/2020. The aims of the present systematic review and meta‐analysis were to investigate…
Effects of exercise training on oxygen uptake in coronary heart disease: a systematic review and meta-analysis
2010
It is not known to what extent exercise programs increase maximal oxygen uptake (VO(2max)) in patients with coronary heart diseases (CHD). The purpose of this study is to determine the effect of exercise interventions on VO(2max) in subjects with CHD. Database search of randomized controlled trials was conducted from PubMed. Studies were included that reported the characteristics and effects of exercise interventions in subjects with CHD, included a non-exercise control group and measured VO(2max) using direct measurement method. Eighteen studies were eligible. Exercise interventions increased VO(2max) by 2.6 +/- 1.6 and 0.3 +/- 1.4 mL/kg/min in the training and control groups, respectively…
On the Randomisation Gallery:Random Reflections on a Popular Method in Medical Research
2016
Objective: Randomized controlled trials (RCTs) and meta-analysis are increasingly utilized methods in medicine. There is, however, substantial critique on both from the theoretical as well as from the practical side. Methods: Seven points on RCTs and three on meta-analysis were choosen to summarize the current critique. Studies critically reviewing the quality of meta-analyses in various fields of medicine were narratively reviewed. Results: The typical RCT is short, performed on a small group of selected patients without severe comorbidity. It is expensive and favors drugs over other forms of therapies. Furthermore, neither patients nor doctors much like RCTs, they feel restricted in their…
Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-ana…
2020
Summary Background The timing of renal replacement therapy (RRT) for severe acute kidney injury is highly debated when no life-threatening complications are present. We assessed whether a strategy of delayed versus early RRT initiation affects 28-day survival in critically ill adults with severe acute kidney injury. Methods In this systematic review and individual patient data meta-analysis, we searched MEDLINE (via PubMed), Embase, and the Cochrane Central Register of Controlled Trials for randomised trials published from April 1, 2008, to Dec 20, 2019, that compared delayed and early RRT initiation strategies in patients with severe acute kidney injury. Trials were eligible for inclusion …
Efficacy of subcutaneous and sublingual immunotherapy with grass allergens for seasonal allergic rhinitis: a meta-analysis–based comparison
2012
Background: Subcutaneous (SCIT) and sublingual (SLIT) immunotherapy are the 2 most prescribed routes for administering allergen-specific immunotherapy. They were shown to be effective in control of symptoms and in reducing rescue medication use in patients with allergic diseases, but their effectiveness has to be balanced against side effects. In recent years, SLIT has been increasingly prescribed, instead of SCIT, because of improved safety and easy administration. Objective: We assessed which route is the most effective in the treatment of patients with seasonal allergic rhinitis to grass pollen. Methods: An indirect meta-analysis–based comparison between SCIT and SLIT was performed. Trea…
Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review
2015
Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes af…
Meta-analysis of the efficacy of different training strategies in animal models of ischemic stroke.
2013
Background and Purpose— Although several studies have shown beneficial effects of training in animal stroke models, the most effective training strategy and the optimal time to initiate training have not been identified. The present meta-analysis was performed to compare the efficacy of different training strategies and to determine the optimal time window for training in animal stroke models. Methods— We searched the literature for studies analyzing the efficacy of training in animal models of ischemic stroke. Training was categorized into forced physical training, voluntary physical training, constraint-induced movement therapy, and skilled reaching training. Two reviewers independently …