Search results for "Metas"

showing 10 items of 1693 documents

Un enfoque de educación física y salud a la luz de la perspectiva de metas: los contextos de clase y la motivación del alumnado

1995

El propósito de este capítulo es presentar los aspectos principales de la teoría de las metas de logro y su utilidad para comprender la motivación del alumnado al realizar actividad física. Nos centraremos en un enfoque de educación física y salud y analizaremos cómo un tipo de metas está relacionado con unas estructuras concretas que surgen en la clase de educación física (tareas o actividades de aprendizaje, la autonomía y responsabilidad del alumnado y la evaluación). Asimismo, comentaremos el papel del profesorado para conseguir crear un ambiente que induzca a unas metas deseables, facilitadoras de experiencias educativas recompensantes, satisfactorias y emancipadoras. Todo ello lo ilus…

educación físicasaludaproximación cualitativaclimas de claseUNESCO::PSICOLOGÍAautonomía del alumnadometas de logroUNESCO::PEDAGOGÍA
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The [Fe(etz)6](BF4)2 Spin-Crossover System—Part One: High-Spin ⇌ Low-Spin Transition in Two Lattice Sites

1996

The [Fe(etz),](BF,), spin-cross-over system (etz = 1-ethyl-1 H-tetrazole) crystallizes in space group P1, with the following lattice constants at 298 K: a 10.419(3), b=15.709(1), c = 18.890(2) A = = 71.223(9), =77.986(10), and = 84.62(1)° V = 2862.0(9) A3 and Z = 3. Two nonequivalent lattice sites, one without (site A) and one with (site B) inversion symmetry, are observed. The population of the two sites nA:nB is 2:l. Iron(II) on site A undergoes a thermal low-spin (LS) high-spin (HS) transition with T1/2I, = 105 K. whereas that on site B remains in the high-spin state down to cryogenic temperatures. Application of external pressure of up to 1200 bar between 200 and 60 K does not cause for…

education.field_of_studyChemistryOrganic ChemistryPopulationPoint reflectionSpin transitionGeneral ChemistryCatalysisExternal pressureCrystallographyNuclear magnetic resonanceLattice constantSpin crossoverMetastabilityLattice (order)educationChemistry - A European Journal
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Lifetime measurements of the 3D3/2 and 3D5/2 metastable states in CaII

1993

The lifetime of the metastable 3D3/2 and 3D5/2 states of Ca+ ions is determined in a r.f. ion trap by laser excitation of this levels and subsequent time delayed probing of the state population by a second laser. In a buffer gas atmosphere of about 10−5−10−6 mbar of He we observe quenching to the ground state and strong finestructure mixing of the two D-states. This mixing allowes only the determination of the combined lifetime. Our result of τ(3D)=1.24(39) s is in good agreement with theoretical calculations.

education.field_of_studyMaterials scienceBuffer gasPopulationLaserAtomic and Molecular Physics and OpticsIonlaw.inventionlawExcited stateMetastabilityIon trapAtomic physicsGround stateeducationZeitschrift f�r Physik D Atoms, Molecules and Clusters
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Energy transfer in diiodoBodipy-grafted upconversion nanohybrids.

2015

Steady-state and time-resolved emission studies on nanohybrids consisting of NaYF4:Yb,Er and a diiodo-substituted Bodipy (UCNP-IBDP) show that the Yb(3+) metastable state, formed after absorption of a near-infrared (NIR) photon, can decay via two competitive energy transfer processes: sensitization of IBDP after absorption of a second NIR photon and population of Er(3+) excited states.

education.field_of_studyPhotonMaterials scienceEnergy transferPopulationPhysics::OpticsNanotechnologyAstrophysics::Cosmology and Extragalactic Astrophysics02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologyPhotochemistry01 natural sciencesPhoton upconversion0104 chemical scienceschemistry.chemical_compoundchemistryExcited stateMetastabilityGeneral Materials ScienceBODIPY0210 nano-technologyAbsorption (electromagnetic radiation)educationAstrophysics::Galaxy AstrophysicsNanoscale
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Extracellular heat shock proteins in cancer: From early diagnosis to new therapeutic approach

2021

In cancer, human cells lose the ability to properly control the series of events that occur constantly during cell growth and division, including protein expression, stability, and dynamics. Heat shock proteins (Hsps) are key molecules in these events, constitutively expressed at high levels and could furthermore be induced by the response to cancer-induced stress. In tumor cells, Hsps have been shown to be implicated in the regulation of apoptosis, immune responses, angiogenesis and metastasis; in some cases, they can be overexpressed and dysregulated, representing important cancer hallmarks. In the past few years, it has been demonstrated that Hsps can be released by tumor cells through s…

endocrine systemCancer ResearchAngiogenesisApoptosischemical and pharmacologic phenomenaBiologyMetastasisImmune systemNeoplasmsHeat shock proteinBiomarkers TumorTumor MicroenvironmentmedicineExtracellularHumansHeat-Shock ProteinsEarly Detection of CancerTumor microenvironmentSettore BIO/16 - Anatomia UmanaCell growthCancerextracellular vesicles Heat shock proteins Liquid biopsyMolecular chaperones.Cancerhemic and immune systemsmedicine.diseaseCell biologybiological sciencesSeminars in Cancer Biology
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Effects of anti-miR-182 on TSP-1 expression in human colon cancer cells: there is a sense in antisense?

2013

Abstract: Objective: miRNAs are attractive molecules for cancer treatment, including colon rectal cancer (CRC). We investigate on the molecular mechanism by which miR-182 could regulate thrombospondin-1 (TSP-1) expression, a protein down-regulated in CRC and inversely correlated with tumor vascularity and metastasis. Background: MicroRNAs are small non-coding RNAs that regulate the expression of different genes, involved in cancer progression, angiogenesis and metastasis. miR-182, over-expressed in colorectal cancer (CRC), has like predictive target thrombospondin-1 (TSP-1), a protein inversely correlated with tumor vascularity and metastasis that results downregulated in different types of…

endocrine systemPathologymedicine.medical_specialtyColorectal cancerAngiogenesisSettore MED/06 - Oncologia MedicaClinical BiochemistryEnzyme-Linked Immunosorbent AssayBiologyReal-Time Polymerase Chain ReactionMetastasisThrombospondin 1immune system diseasesCell Line TumorDrug DiscoverymicroRNAThrombospondin 1Sense (molecular biology)medicineHumansPromoter Regions GeneticDNA PrimersPharmacologyBase SequencePharmacology. Therapyvirus diseasesCancerTransfectionOligonucleotides Antisensemedicine.diseaseMicroRNAsCancer researchanti-miR-182 colon cancer Egr-1 Sp-1 thrombospondin-1Molecular MedicineColorectal Neoplasms
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A CRF-Producing and -Secreting Tumor of the Lung

1986

Corticotropin-releasing factor (CRF) has recently been isolated from ovine hypothalamus, characterized chemically, and synthesized. Upton and Amatruda (1971) first suggested that CRF-like activity occurred in neoplastic tissues, and Hashimoto et al. (1980) subsequently detected CRF-like activity in an extract of an ACTHproducing nephroblastoma. Recently, Carey et al. (1984) and Asa et al. (1984) used immunocytochemical techniques to demonstrate CRF in postmortem tumor material obtained from patients with a carcinoma of the prostate and an intrasellar gangliocytoma.

endocrine systemPathologymedicine.medical_specialtyLungbusiness.industryTissue Polypeptide Antigenmedicine.diseasemedicine.anatomical_structureHypothalamusProstateCarcinomaMedicinebusinessCutaneous metastasisGangliocytomaInnominate veinhormones hormone substitutes and hormone antagonists
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Bestiari Llatí Polisemàntic: un Estudi Motivacional

2015

La tesi és un estudi semàntic diacrònic dels cinquanta zoònims llatins més productius de significats figurats o metasèmies; alhora constitueix una anàlisi motivacional de la creació de lèxic nou en general, i zoonímic en particular. Es constata que els zoònims constitueixen segurament el camp semàntic de més capacitat per a un ús figurat metafòric o metonímic. S'analitzen, doncs, les 16 derives semàntiques dels zoònims llatins, que per ordre de major freqüència a menor freqüència són les següents: noms de persona (antropònims), noms de plantes o fruits (fitònims), noms de caràcter, especialment insults i termes afectuosos (etònims), noms de lloc (topònims), noms d'animals procedents de noms…

etimologiateoria de la continuïtat paleolíticaiconímiasemànticafonosimbolisme:ANTROPOLOGÍA [UNESCO]metasèmiatabú venatoriantroponímiaUNESCO::ANTROPOLOGÍAzoònimBallestermetàforaonomatopeiazootropiaindoeuropeuasilusproductivitat motivacionaldiacronia diacrònictabú lingüísticcanvi semànticcòpia lingüísticaulciscimotivació lingüísticahirundo hirudozoonímiaUNESCO::LINGÜÍSTICAmetonímiaanimalsanimal studiesulcusantropologiahuman-animal studies:LINGÜÍSTICA [UNESCO]anthrozoologybestiariAlineicaricatura lingüísticadialectesOrovalcolubrapolisèmiacalc lingüístic
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New Frontiers in Cancer Imaging and Therapy Based on Radiolabeled Fibroblast Activation Protein Inhibitors: A Rational Review and Current Progress.

2021

Over the past decade, the tumor microenvironment (TME) has become a new paradigm of cancer diagnosis and therapy due to its unique biological features, mainly the interconnection between cancer and stromal cells. Within the TME, cancer-associated fibroblasts (CAFs) demonstrate as one of the most critical stromal cells that regulate tumor cell growth, progression, immunosuppression, and metastasis. CAFs are identified by various biomarkers that are expressed on their surfaces, such as fibroblast activation protein (FAP), which could be utilized as a useful target for diagnostic imaging and treatment. One of the advantages of targeting FAP-expressing CAFs is the absence of FAP expression in q…

fibroblast activation proteincongenital hereditary and neonatal diseases and abnormalitiesStromal cellmedicine.medical_treatmentcancer-associated fibroblastPharmaceutical Science610 Medicine & healthCancer imagingReviewfibroblast activation protein inhibitorMetastasisPharmacy and materia medicaFibroblast activation protein alphaDrug Discoverymedicinetumor microenvironment610 Medicine & healthneoplasmsradiotherapynuclear imagingTumor microenvironmentbusiness.industryRCancerImmunosuppressionmedicine.diseasedigestive system diseasesRadiation therapyRS1-441Cancer researchMolecular MedicineMedicinebusiness
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Equilibrium fluid-crystal interfacial free energy of bcc-crystallizing aqueous suspensions of polydisperse charged spheres

2015

The interfacial free energy is a central quantity in crystallization from the meta-stable melt. In suspensions of charged colloidal spheres, nucleation and growth kinetics can be accurately measured from optical experiments. In previous work, from this data effective non-equilibrium values for the interfacial free energy between the emerging bcc-nuclei and the adjacent melt in dependence on the chemical potential difference between melt phase and crystal phase were derived using classical nucleation theory. A strictly linear increase of the interfacial free energy was observed as a function of increased meta-stability. Here, we further analyze this data for five aqueous suspensions of charg…

fluid-crystalMaterials scienceNucleationFOS: Physical sciencesThermodynamicsNon-equilibrium thermodynamicsCondensed Matter - Soft Condensed Matter01 natural scienceslaw.inventionColloidlawMetastability0103 physical sciencesCrystallization010306 general physicsCondensed Matter - Statistical MechanicsCondensed Matter - Materials ScienceAqueous solutionStatistical Mechanics (cond-mat.stat-mech)010304 chemical physicsMaterials Science (cond-mat.mtrl-sci)Condensed Matter::Soft Condensed Matterpolydisperseinterfacial free energySoft Condensed Matter (cond-mat.soft)SPHERESClassical nucleation theoryPhysical Review E
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