Search results for "Method"
showing 10 items of 13253 documents
In Vivo Reprogramming for Brain and Spinal Cord Repair.
2015
AbstractCell reprogramming technologies have enabled the generation of various specific cell types including neurons from readily accessible patient cells, such as skin fibroblasts, providing an intriguing novel cell source for autologous cell transplantation. However, cell transplantation faces several difficult hurdles such as cell production and purification, long-term survival, and functional integration after transplantation. Recently,in vivoreprogramming, which makes use of endogenous cells for regeneration purpose, emerged as a new approach to circumvent cell transplantation. There has been evidence forin vivoreprogramming in the mouse pancreas, heart, and brain and spinal cord with …
Search for the neutral Higgs bosons of the Minimal Supersymmetric Standard Model in $pp$ collisions at $\sqrt{s}=7$ TeV with the ATLAS detector
2013
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb[superscript −1] to 4.8 fb[superscript −1]. Higgs boson decays into oppositely-charged muon or τ lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits ar…
"Table 3" of "Measurements of the charge asymmetry in top-quark pair production in the dilepton final state at $\sqrt{s}=8$ TeV with the ATLAS detect…
2017
The leptonic inclusive asymmetry in the fiducial volume.
Combined Innovation Policy: Linking Scientific and Practical Knowledge in Innovation Systems
2012
New research indicates that firms combining the science-based STI (Science, Technology, Innovation) and the experience-based DUI (Doing, Using, Interacting) modes of innovation are more efficient when it comes to improving innovation capacity and competitiveness. With regard to innovation policy, the STI mode calls for a supply driven policy, typically aimed to commercialise research results. The DUI mode suggests a demand driven policy approach, such as supporting the development of new products or services to specific markets. This paper analyses how the two types of innovation policy and the two innovation modes can be combined in regional innovation systems. The analysis builds on studi…
Formulations and exact algorithms for the distance-constrained generalized directed rural postman problem
2017
[EN] The generalized directed rural postman problem is an arc routing problem with many interesting real-life applications, such as routing for meter reading. In this application, a vehicle with a receiver travels through a series of neighborhoods. If the vehicle gets closer than a certain distance to a meter, the receiver is able to record the gas, water, or electricity consumption. Therefore, the vehicle does not need to traverse every street, but only a few, to get close enough to each meter. We study an extension of this problem in which a fleet of vehicles is available. Given the characteristics of the mentioned application, the vehicles have no capacities but there is a maximum distan…
STABILITY OF A STOCHASTICALLY PERTURBED MODEL OF INTRACELLULAR SINGLE-STRANDED RNA VIRUS REPLICATION
2019
Compared to the replication of double-stranded RNA and DNA viruses, the replication of single-stranded viruses requires the production of a number of intermediate strands that serve as templates for the synthesis of genomic-sense strands. Two theoretical extreme mechanisms for replication for such single-stranded viruses have been proposed; one extreme being represented by the so-called linear stamping machine and the opposite extreme by the exponential growth. Of course, real systems are more complex and examples have been described in which a combination of such extreme mechanisms can also occur: a fraction of the produced progeny resulting from a stamping-machine type of replication that…
Servicios de intermediación en línea en Europa : diseño de un sistema específico de solución de controversias
2021
Este trabajo analiza el sistema de solución de controversias específicamente diseñado, con la introducción de alternativas a la jurisdicción, en el Reglamento (UE) 2019/1150 sobre el fomento de la equidad y la transparencia para los usuarios profesionales de servicios de intermediación en línea, que ha entrado recientemente en vigor.
Development of Artificial Intelligence Methods for Clinical Genomics
2022
El presente trabajo de investigación se centra en la identificación de puntos de majora de los actuales sistemas de análisis genético y de recuento cellular para laboratorio. Analiza las diferentes metodologías existentes a través de encuestas a expertos, investigación bibliográfica y experimentos comparativos. Posteriormente propone varias metodologías mejoradas para recuento celular basadas en inteligencia artificial aplicada al análisis de imágen y para automatización de análisis genéticos en sistemas de secuenciación masiva NGS. El trabajo también propone varias optimizaciones para interpretación de variantes genéticas mediante inteligencia artificial a partir de una variación de la met…
Portales educativos : la producción de materiales didácticos digitales
2018
El objetivo principal de este artículo es conocer cómo se organiza la producción de los materiales didácticos digitales de creación propia de portales institucionales de recursos educativos, tomando como referencia la perspectiva de sus principales responsables. En concreto, se analiza el caso del repositorio institucional de recursos de la Comunidad Autónoma de Canarias, Ecoescuela 2.0; y del portal de recursos educativos en abierto Procomún (Ministerio de Educación, Cultura y Deporte). Con este estudio se pretende dar respuesta a distintas cuestiones relacionadas con la autoría de los materiales, el proceso y desarrollo, así como los criterios que establecen los portales institucionales p…
An application of the case study in the Zaragoza University Masters’ Teacher Training
2016
Los cambios metodológicos propuestos por el Espacio Europeo de Educación Superior (EEES) han propiciado la aplicación del método del estudio de caso en distintas enseñanzas. En este estudio se analiza la aplicación del método del caso en el Máster en Profesorado de la Universidad de Zaragoza. Este estudio se ha aplicado en dos grupos de estudiantes de distintas especialidades (Ciencias Naturales y Ciencias Experimentales) de la asignatura de Interacción y convivencia en el aula, formando una muestra conjunta de 98 estudiantes (N=98). Con el fin de analizar los resultados de aprendizaje obtenidos a través del método del caso y de la asignatura, se ha comprobado si existe una relación entre l…