Search results for "Metronidazol"

showing 10 items of 46 documents

Development of a Multifunctional Bioerodible Nanocomposite Containing Metronidazole and Curcumin to Apply on L-PRF Clot to Promote Tissue Regeneratio…

2020

Teeth extractions are often followed by alveolar bone reabsorption, although an adequate level of bone is required for reliable rehabilitations by dental implants. Leukocyte and platelet-rich fibrin (L-PRF) has been widely applied in regenerative procedures and with antibiotic and antioxidant agents could play an essential role in hard and soft tissue healing. In this work, a nanocomposite (Sponge-C-MTR) consisting of a hyaluronate-based sponge loaded with metronidazole (MTR) and nanostructured lipid carriers containing curcumin (CUR-NLC) was designed to be wrapped in the L-PRF&trade

Sonicationnanostructured lipid carriersMedicine (miscellaneous)02 engineering and technologynanostructured lipid carrier030226 pharmacology & pharmacyhydrophilic spongeGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemetronidazolebone regenerationSettore MED/28 - Malattie OdontostomatologicheHyaluronic acidhyaluronic acidZeta potentialcurcuminBone regenerationlcsh:QH301-705.5Dental alveolustooth extractionNanocompositenanocompositeChemistryRegeneration (biology)hyaluronic acid.L-PRFBuccal administration021001 nanoscience & nanotechnologylcsh:Biology (General)Settore CHIM/09 - Farmaceutico Tecnologico Applicativo0210 nano-technologyBiomedical engineeringBiomedicines
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Comparative evaluation of anti microbial effects of triple antibiotic paste and amox and its derivatives against E. Faecalis : an in vitro study

2017

Background Enterococcus faecalis is a microorganism commonly detected in asymptomatic, persistent endodontic infections. Triple antibiotic paste has stood the test of time as a proven antibiotic combination against E. Faecalis. However, problems with this include staining of teeth and standardization of the preparation. Thus, the search for better alternatives and better preparation techniques is still on. Aim To observe the potential of combinations [(Amoxicillin+ Metronidazole, Amoxicillin Clavulanic Acid + Metronidazole; Amoxicillin and Cloxacillin + Metronidazole)] over Triple Antibiotic Paste. Material and methods Fifty single rooted teeth free from dental caries were selected for the …

Veterinary medicineAmoxicillin/clavulanic acidbiologymedicine.drug_classRoot canalAntibiotics030206 dentistryAmoxicillinbiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]Enterococcus faecalisMicrobiology03 medical and health sciencesMetronidazole0302 clinical medicineCloxacillinmedicine.anatomical_structureClavulanic acidUNESCO::CIENCIAS MÉDICASmedicineGeneral Dentistry030217 neurology & neurosurgerymedicine.drug
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High resistance against clindamycin, metronidazole and amoxicillin in Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans isolates of …

2010

Objectives: To test the antimicrobial sensitivity of two periodontal pathogens to a panel of five orally administrable antibiotics in periodontal disease. Study design: A total of 69 isolates of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis were processed using culture and biochemical tests. Selected colonies of A. actinomycetemcomitans and P. gingivalis were used to evaluate the antibacterial activity of clindamycin, metronidazole, amoxicillin, moxifloxacin and amoxicillin/clavulanic acid. Results: Susceptibility testing revealed a sensitivity of 100% of A. actinomycetemcomitans and P. gingivalis to moxifloxacin and amoxicillin/clavulanic acid but moderate susceptibili…

biologymedicine.drug_classbusiness.industryAntibioticsAggregatibacter actinomycetemcomitansDrug resistanceAmoxicillin:CIENCIAS MÉDICAS [UNESCO]biology.organism_classificationAntimicrobialMicrobiologyMetronidazoleOtorhinolaryngologyClavulanic acidUNESCO::CIENCIAS MÉDICASmedicineSurgerybusinessGeneral DentistryPorphyromonas gingivalismedicine.drugMedicina Oral Patología Oral y Cirugia Bucal
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Taxonomical and Functional Assessment of the Endometrial Microbiota in A Context of Recurrent Reproductive Failure: A Case Report

2019

Investigation of the microbial community in the female reproductive tract has revealed that the replacement of a community dominated by Lactobacillus with pathogenic bacteria may be associated with implantation failure or early spontaneous abortion in patients undergoing assisted reproductive technology (ART) treatment. Herein we describe taxonomically and functionally the endometrial microbiome of an infertile patient with repeated reproductive failures (involving an ectopic pregnancy and two clinical miscarriages). The microbiological follow-up is presented over 18-month in which the microbiota was evaluated in six endometrial fluid samples. The microbial profile of 16S rRNA gene sequenci…

clinical miscarriage0301 basic medicineMicrobiology (medical)Atopobiummedicine.medical_treatment030106 microbiologylcsh:MedicinePhysiology<i>gardnerella vaginalis</i>Case ReportContext (language use)reproductive failuremedicine.disease_causeMiscarriagemetronidazole resistance03 medical and health sciencesGardnerellamedicineImmunology and AllergyGardnerella vaginalisMicrobiomeMolecular Biology16S rRNA gene sequencingendometrial microbiotaAssisted reproductive technologyGeneral Immunology and Microbiologybiologylcsh:Rbiology.organism_classificationmedicine.diseaseGardnerella vaginalis030104 developmental biologyInfectious DiseasesMetagenomicsbiofilm formationectopic pregnancywhole metagenome sequencingPathogens
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Estudio de la modificación en la absorción de fármacos en giardiasis y nuevas estrategias de formulación

2016

Giardia intestinalis es el agente causal de la giardiasis, una de las patologías intestinales más comunes en todo el mundo, cuya sintomatología principal es diarrea y malabsorción. La OMS indica que la prevalencia mundial es de 200 millones de individuos afectando especialmente a niños entre 2 y 12 años, los cuales son en su mayoría asintomáticos. Diversos estudios demuestran que existe un riesgo importante en la población infantil, pues la carencia de vitaminas y otros nutrientes que provoca esta parasitosis puede ocasionar graves desórdenes, como anemia, retraso del crecimiento y discapacidad intelectual. Aunque el efecto de Giardia sobre la absorción de nutrientes y vitaminas se ha estud…

cultivo celularpermeabilidadin situMetronidazolin vitroCaco-2Giardia intestinalis:CIENCIAS MÉDICAS [UNESCO]hidrogelgiardiasismicroparticulasrata wistarUNESCO::CIENCIAS MÉDICAS
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Metronidazole/montmorillonite nanodevices for controlled drug delivery

2014

drug delivery system clay montmorillonite metronidazole adsorption
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Vulvar involvement in pediatric Crohn’s disease: a systematic review

2018

Purpose: The aim of the study is to report a systematic review (from 2000 to 2017) of all pediatric cases of vulvar Crohn’s disease (VCD) and to highlight the key-points for a correct diagnosis and management of this rare condition. Methods: An electronic search using the Pubmed/Medline, Scopus, EMBASE, Cochrane database and Google Scholar database was performed according to PRISMA guidelines. Results: Twenty pediatric studies and 22 cases of VCD were included for analysis. All the articles reported a single case, except two articles where two cases, respectively, are described. Clinical vulvar examination showed the following main manifestations: vulvar erythema (9/22 cases, 40.9%), vulv…

endocrine systemmedicine.medical_specialtyPediatric Crohn's diseaseVulvar edemaAdministration TopicalAdministration OralDiseasePerineumGastroenterologyVulvaPediatric Crohn’s disease030207 dermatology & venereal diseases03 medical and health sciencesPediatric Crohn’s disease0302 clinical medicineCrohn DiseaseObstetrics and gynaecologyMetronidazoleInternal medicineEdemaHumansMedicineVulvar diseaseChildbusiness.industryObstetrics and GynecologyGeneral MedicineDermatologyExtra-intestinal Crohn’s disease030220 oncology & carcinogenesisVulvar edemaFemaleVulvar DiseasesExtra-intestinal Crohn’s diseasebusinessExtra-intestinal Crohn’s disease; Pediatric Crohn’s disease; Vulvar disease; Vulvar edema; Obstetrics and Gynecology
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Helicobacter pylori first-line and rescue treatments in patients allergic to penicillin: Experience from the European Registry on H pylori management…

2020

Background Experience in Helicobacter pylori eradication treatment of patients allergic to penicillin is very scarce. A triple combination with a PPI, clarithromycin (C), and metronidazole (M) is often prescribed as the first option, although more recently the use of a quadruple therapy with PPI, bismuth (B), tetracycline (T), and M has been recommended. Aim To evaluate the efficacy and safety of first-line and rescue treatments in patients allergic to penicillin in the "European Registry of H pylori management" (Hp-EuReg). Methods A systematic prospective registry of the clinical practice of European gastroenterologists (27 countries, 300 investigators) on the management of H pylori infect…

medicine.medical_specialtyAllergySettore MED/12 - GASTROENTEROLOGIAallergicPenicillinsGastroenterologyHelicobacter InfectionsDrug Hypersensitivity03 medical and health sciences0302 clinical medicineLevofloxacinMetronidazoleClarithromycinInternal medicinebismuthmedicineHumansProspective StudiesRegistriesAdverse effectlevofloxacinbiologyHelicobacter pyloribusiness.industrySettore MED/09 - MEDICINA INTERNAallergic ; allergy ; bismuth ; clarithromycin ; Helicobacter pylori ; levofloxacin ; penicillinGastroenterologyProton Pump InhibitorsGeneral MedicineTetracyclineHelicobacter pyloribiology.organism_classificationmedicine.diseaseallergyclarithromycinAnti-Bacterial Agents3. Good healthPenicillinMetronidazoleRegimenInfectious Diseasespenicillin030220 oncology & carcinogenesisDrug Therapy Combination030211 gastroenterology & hepatologybusinessmedicine.drug
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Interventionelle ERCP bei Patienten mit Cholestase: Häufigkeit und Antibiotikaresistenz der biliären Keimbesiedlung

2001

Interventional ERCP in patients with cholestasis. Degree of biliary bacterial colonization and antibiotic resistance. Biliary obstruction together with bacterial colonization of the bile duct may lead to development of acute cholangitis. The aim of our prospective study was to investigate the presence and degree of biliary bacterial colonization by means of bile aspiration during ERCP in patients with biliary obstruction. Furthermore, we evaluated antibiotic therapy regimens, which would cover the bacterial species obtained by ERCP and subsequent culture in each patient. In addition, analysis of risk factors was performed that would predispose to the development of cholangitis.80 patients w…

medicine.medical_specialtyBile ductbusiness.industryGastroenterologymedicine.diseasedigestive systemGastroenterologydigestive system diseasesMetronidazolemedicine.anatomical_structureCholestasisLevofloxacinBacteremiaInternal medicinemedicineCeftriaxoneAnaerobic bacteriabusinessmedicine.drugAntibacterial agentZeitschrift für Gastroenterologie
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Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective

2013

Purpose Treatment with cetuximab is accompanied by the development of an acneiform follicular skin exanthema in more than 80 % of patients. Severe exanthema (grade III/IV) develops in about 9–19 % of patients with the necessity of cetuximab dose reduction or cessation.

medicine.medical_specialtyCancer ResearchHematologyCetuximabintegumentary systembusiness.industryGeneral MedicineMinocyclineRashDermatologydigestive system diseasesSurgeryMetronidazoleOncologyInternal medicineMonoclonalmedicinePrednisolonemedicine.symptomAntibiotic prophylaxisbusinessneoplasmsmedicine.drugJournal of Cancer Research and Clinical Oncology
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