Search results for "Mg"

Redox signaling in acute pancreatitis

2015

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium, cathepsins, pH disorders, autophagy, and cell death, particularly necrosis. This review focuses on the new role of redox signaling in acute pancreatitis. Oxidative stress and redox status are involved in the onset of acute pancreatitis and also in the development of the systemic inflammatory response, being glutathione depletion, xanthine oxidase activation, and thiol oxidation in proteins critical features of the disease in the pancreas. On th…

Testing microscopically derived descriptions of nuclear collectivity: Coulomb excitation of Mg-22

2018

Many-body nuclear theory utilizing microscopic or chiral potentials has developed to the point that collectivity might be dealt with in an {\it ab initio} framework without the use of effective charges; for example with the proper evolution of operators, or alternatively, through the use of an appropriate and manageable subset of particle-hole excitations. We present a precise determination of $E2$ strength in $^{22}$Mg and its mirror $^{22}$Ne by Coulomb excitation, allowing for rigorous comparisons with theory. No-core symplectic shell-model calculations were performed and agree with the new $B(E2)$ values while in-medium similarity-renormalization-group calculations consistently underpre…

Hybrid density functional calculations of hyperfine coupling tensor for hole-type defects in MgAl2O4

2020

This work has been performed within the framework of the EUROfusion Enabling Research project: ENR-MFE19.ISSP-UL-02 “Advanced experimental and theoretical analysis of defect evolution and structural disordering in optical and dielectric materials for fusion application”. The views and opinions expressed herein do not necessarily reflect those of the European Commission.

High performance detector head for PET and PET/MR with continuous crystals and SiPMs

2012

International audience; A high resolution PET detector head for small animal PET applications has been developed. The detector is composed of a 12 mm x 12 mm source continuous LYSO crystal coupled to a 64-channel monolithic SiPM matrix from FBK-irst. Crystal thicknesses of 5 mm and 10 mm have been tested, both yielding an intrinsic spatial resolution around 0.7 mm FWHM with a position determination algorithm that can also provide depth-of-interaction information. The detectors have been tested in a rotating system that makes it possible to acquire tomographic data and reconstruct images of 22Na sources. An image reconstruction method specifically adapted for continuous crystals has been emp…

g factors of $^{31,32,33}$Al: Indication for intruder configurations in the $^{33}$Al ground state

2006

Abstract The g factors of 31,32,33 Al have been measured using the β -nuclear magnetic resonance ( β -NMR) technique on spin-polarized beams produced in the fragmentation of a 36 S (77.5 MeV/u) beam on a 9 Be target. Nearly pure beams of Al ( Z = 13 ) isotopes were selected with the high-resolution fragment separator LISE at GANIL. An asymmetry as high as 6% has been observed in the β -NMR curve for 32 Al implanted in a Si single crystal. The magnetic moment of the N = 20 nucleus 33 Al is obtained for the first time: μ ( Al 33 , I π = 5 / 2 + ) = 4.088 ( 5 ) μ N , while those of 31,32 Al are obtained with improved accuracy: μ ( Al 31 , I π = 5 / 2 + ) = 3.830 ( 5 ) μ N and μ ( Al 32 , I π =…

IN CELLULE DI OSTEOSARCOMA UMANO MG-63, IL TRATTAMENTO CON 3-AMINOBENZAMIDE FAVORISCE L’ESPANSIONE DI UNA POPOLAZIONE CELLULARE “STEM-LIKE”

2009

Raman based distributed fiber optic temperature sensors for structural health monitoring in radiation environment

2015

Raman distributed temperature sensor (RDTS) measurements were performed during γ-radiation on three different classes of standard multimode fibers (pure, Ge-doped and F-doped). The sensor response is affected by the radiation induced attenuation phenomena leading to errors in the temperature measurements. The amplitude of this error strongly depends on the fiber type and the irradiation conditions. These results are promising in view of the integration of these RDTS into the deep geological repository for radioactive waste.

Muscle activation during push-ups performed under stable and unstable conditions

2015

Background/Objective: The purpose of this study was to analyze muscle activation when performing push-ups under different stability conditions. Methods: Physically fit young male university students (N = 30) performed five push-ups under stable conditions (on the floor) and using four unstable devices (wobble board, stability disc, fitness dome, and the TRX Suspension Trainer). The push-up speed was controlled using a metronome, and the testing order was randomized. The average amplitudes of the electromyographic (EMG) root mean square of the anterior deltoid (DELT), serratus anterior (SERRA), lumbar multifidus (LUMB), and rectus femoris (FEM) were recorded. The electromyographic signals we…

Correlation between CD117+ myeloma plasma cells and hematopoietic progenitor cells in different categories of patients

2015

Background Multiple myeloma (MM) is a neoplastic disorder of plasma cells interesting mainly the elderly. MM remains an incurable disease, mostly because of the strong interplay between clonal plasma cells (cPCs) and bone marrow (BM) microenvironment. Multiparameter flow cytometry (MFC) allows the simultaneous study of the cPC immunophenotype and alterations involving other cells in BM, but rarely these data are interpreted as connected. One exception to this habit are previous studies about relationship between CD117 cPC positivity and hematopoietic progenitor cell (HPC) distribution in newly diagnosed patients. Thus we were interested in verifying the distribution of BM CD34+ HPCs in heal…

Pharmacogenetics implementation in the clinics: information and guidelines for germline variants.

2018

The aim of this work was to supply an overview of the germline Pharmacogenetics that can be already implemented in the oncology clinical practice. An explanation of the three pillars considered necessary for determining which genetic polymorphisms should be used has been provided. These are PharmGKB single nucleotide polymorphism (SNP)-Drug Clinical Annotations with levels of evidence 1 or 2; the genetic information provided in the drug labels by the drug regulatory main agencies (Food and Drug Administration and European Medicines Agency, mainly); and the guidelines elaborated by international expert consortia (mainly Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacoge…