Search results for "Milan"
showing 10 items of 83 documents
Sedimentary model and high-frequency cyclicity in a Mediterranean, shallow-shelf, temperate-carbonate environment (uppermost Miocene, Agua Amarga Bas…
1996
Uppermost Tortonian to lower Messinian temperate carbonates crop out in the Agua Amarga Basin (SE Spain). They consist of four units. The lower three units can be tentatively assigned to the lowstand systems tract of a fourth-order sequence, constituting in turn the lowstand (‘megatrough unit’), transgressive (‘breccia unit’) and highstand (‘bedded unit’) stages of a higher-order cycle. All these materials were deposited in a small pull-apart basin related to the sinistral Carboneras strike-slip fault system. The best represented is the bedded unit (up to 25 m thick), which consists of bioclastic, bryozoan/bivalve-dominated calcarenites/calcirudites with abundant fragments of echinoids, bar…
Disegno, progetto e anima dei luoghi
2019
Il libro "Quadri per Milano - prove di architettura" (LetteraVentidue, 2017) raccoglie nove progetti su Milano di Angelo Torricelli, elaborati tra il 1991 e il 2017 e ordinati secondo la loro posizione all'interno della città e le soluzioni adottate. Il volume, concepito come il catalogo della mostra organizzata presso il Dipartimento di Architettura di Palermo, ha assunto il carattere di una riflessione con diverse voci sulle relazioni tra rappresentazione / progetto / luogo. I testi intenzionalmente scarsi (dell'autore), che accompagnano i progetti, indicano esclusivamente i motivi e gli obiettivi delle proposte. I tre saggi iniziali e quello conclusivo, d'altra parte, propongono un parti…
Transarterial Chemoembolization Before Liver Transplantation in 60 Patients With Hepatocellular Carcinoma
2007
Tumor recurrence is a major problem after orthotopic liver transplantation (OLT) in patients with hepatocellular carcinoma (HCC). In 60 patients OLT was performed for HCC after pretreatment by repeated transarterial chemoembolization (TACE). Forty-four recipients exceeded the Milan criteria. Recurrence-free 5-year survival was 65.2% and 5-year freedom from recurrence was 73.2%. During the waiting time, 14 patients experienced minimal change, which did not fulfill the definition of tumor progression according to official oncological criteria. Five-year freedom from recurrence among patients with stable compared with progressive disease was 93.3% versus 28.1%, respectively (P = .0001). A stri…
GALAD Score Detects Early Hepatocellular Carcinoma in an International Cohort of Patients With Nonalcoholic Steatohepatitis
2020
Background & Aims The prevalence of nonalcoholic steatohepatitis (NASH) associated hepatocellular carcinoma (HCC) is increasing. However, strategies for detection of early-stage HCC in patients with NASH have limitations. We assessed the ability of the GALAD score, which determines risk of HCC based on patient sex; age; and serum levels of α-fetoprotein (AFP), AFP isoform L3 (AFP-L3), and des-gamma-carboxy prothrombin (DCP), to detect HCC in patients with NASH. Methods We performed a case-control study of 125 patients with HCC (20% within Milan Criteria) and 231 patients without HCC (NASH controls) from 8 centers in Germany. We compared the performance of serum AFP, AFP-L3, or DCP vs GALAD …
Liver transplantation as a primary indication for intrahepatic cholangiocarcinoma: a single-center experience.
2008
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is not a widely accepted indication for orthotopic liver transplantation (OLT). The present study describes our institutional experience with patients who underwent transplantation for ICC as well as those with ICC who underwent transplantation with the incorrect diagnosis of hepatocellular carcinoma (HCC). Patients and Methods Data corresponding to ICC patients were reviewed for the purposes of this study. Patients with hilar cholangiocarcinoma and incidentally found ICC after OLT for benign diseases were excluded from further consideration. Results Among the 10 patients, 6 underwent transplantation before 1996 and 4 after 2001. Tho…
An Intention-to-Treat Competing-Risk Model for Candidates with Hepatocellular Cancer Awaiting Liver Transplantation
2018
Background: Since the introduction of the Milan Criteria (MC), all systems, which describe post-transplant prognosis of patients with hepatocellular cancer (HCC), are exclusively based on characteristics available at surgery, and neglect the intention-to-treat principles. This study, based on a large international HCC patient cohort, aimed to develop comprehensive intention-to-treat models through a competing-risk analysis. We used data available at first referral to predict the risk of delisting and HCC-related death after liver transplantation (LT). Methods: Twelve centres in the United States, Europe and Asia created a Derivation Set (n=2,318) and an external Validation Set (n=773) of …
Milan criteria, up-to-seven criteria, and the illusion of a rescue package for patients with liver cancer
2009
Il MemorIale In Onore degli Italiani Caduti nei campi di Sterminio Nazisti
2013
Se prima della guerra l’esperienza dei Bbpr poteva inquadrarsi all’interno del movimento razionalista, ideando progetti come le Colonie elioterapiche di Legnano (1932) e vari piani regolatori, (Pavia, Isola d’Elba, Valle d’Aosta), la barbarie della guerra mutò tale visione, operando una significativa rifondazione del gruppo stesso, in un rinnovato rapporto con il potere e la realtà: il Monumento ai morti nei lager del Cimitero monumentale di Milano (1946) ne è espressione emblematica. Seguirono progetti storici: Torre Velasca (1958), il Memoriale di Gusen (1960) e progetti di una nuova cultura architettonica che contribuì ad affermare una scuola sviluppatasi soprattutto attorno al Politecni…