Search results for "Mitral"

showing 10 items of 146 documents

Predictors of short‐ and long‐term outcomes of patients undergoing transcatheter mitral valve edge‐to‐edge repair

2020

Objectives Transcatheter mitral valve repair (TMVR) by edge-to-edge therapy is an established treatment for severe mitral valve regurgitation (MR). Background Symptomatic and prognostic benefit in functional MR has been shown recently; nevertheless, data on long-term outcomes are sparse. Methods and results We analyzed survival of patients treated with isolated edge-to-edge repair from June 2010 to March 2018 (primarily combined edge-to-edge repair with other mitral valve interventions was excluded) in a retrospective monocentric study. Overall, 627 consecutive patients (47.0% females, 78.6 years in mean) were included. Leading etiology was functional MR (57.4%). Follow-up regarding surviva…

MaleCardiac Catheterizationmedicine.medical_specialtymedicine.medical_treatmentDischarged alive030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineMitral valveLong term outcomesmedicineHumansRadiology Nuclear Medicine and imaging030212 general & internal medicineRetrospective StudiesHeart Valve Prosthesis ImplantationCOPDMitral valve repairMitral regurgitationbusiness.industryMitral Valve InsufficiencyGeneral Medicinemedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureEtiologyMitral ValveFemaleCardiology and Cardiovascular MedicineMitral valve regurgitationbusinessCatheterization and Cardiovascular Interventions
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Portraying infective endocarditis

2019

Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients …

MaleInternationalityAucunInfective endocarditimedicine.disease_causeMedical microbiology80 and overBlood cultureHospital MortalityAged 80 and overmedicine.diagnostic_testbiologyEndocarditisSBacterialGeneral MedicineSciences bio-médicales et agricolesMiddle AgedStaphylococcal InfectionsSciences du Vivant [q-bio]/Microbiologie et ParasitologieViridans StreptococciCatheterInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyStaphylococcus aureusInfective endocarditisAortic ValveMitral ValveFemaleMicrobiology (medical)Adultmedicine.medical_specialtyProsthesis-Related InfectionsAdolescentaureusBlood cultureYoung AdultInternal medicinemedicineEndocarditisHumansresults of multinational ID-IRI study- EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES cilt.38 ss.1753-1763 2019 [Erdem H. Puca E. Ruch Y. Santos L. Ghanem-Zoubi N. Argemi X. Hansmann Y. Guner R. Tonziello G. Mazzucotelli J. et al. -Portraying infective endocarditis]ProstheticAgedNative Valve EndocarditisBacteriabusiness.industryEndocarditis Bacterialmedicine.diseasebiology.organism_classificationS. aureusViridans streptococciInfective endocarditisbusinessNative
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A Comparison of 2 Mitral Annuloplasty Rings for Severe Ischemic Mitral Regurgitation: Clinical and Echocardiographic Outcomes.

2016

Controversies regarding the choice of annuloplasty rings for treatment of ischemic mitral regurgitation still exist. Aim of the study is to compare early performance of 2 different rings in terms of rest and exercise echocardiographic parameters (transmitral gradient, systolic pulmonary artery pressure, and mitral valve area), clinical outcomes, and recurrence of mitral regurgitation. From January 2008 till December 2013, prospectively collected data of patients who underwent coronary artery bypass grafting and undersizing mitral valve annuloplasty for severe chronic ischemic mitral regurgitation at our Institution were reviewed. A total of 93 patients were identified; among them 44 had sem…

MaleMitral Valve AnnuloplastyTime FactorsMyocardial IschemiaHemodynamics030204 cardiovascular system & hematologySeverity of Illness IndexVentricular Function Left0302 clinical medicinePostoperative ComplicationsRecurrenceMitral valve annuloplastyMitral valve030212 general & internal medicineHospital MortalityHeart Valve Prosthesis ImplantationExercise ToleranceIschemic mitral regurgitationMitral Valve InsufficiencyGeneral MedicineMiddle Agedmedicine.anatomical_structureTreatment OutcomeItalyHeart Valve ProsthesisCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicineArteryEchocardiography StressPulmonary and Respiratory Medicinemedicine.medical_specialtyProsthesis Design03 medical and health sciencesInternal medicinemedicine.arterymedicineHumansMitral AnnuloplastyAgedRetrospective StudiesMitral regurgitationbusiness.industryRecovery of FunctionSurgeryPulmonary arteryChronic DiseaseExercise TestSurgerybusinessSeminars in thoracic and cardiovascular surgery
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Inhaled Prostacyclin, Nitric Oxide, and Nitroprusside in Pulmonary Hypertension After Mitral Valve Replacement

2005

Abstract Objective: Pulmonary hypertension increases morbidity and mortality in patients undergoing heart surgery. Mitral valve stenosis is frequently associated with an increase in pulmonary vascular resistance (PVR). Cardiopulmonary bypass exacerbates pulmonary hypertension in patients undergoing cardiac surgery. The aim of this study was to compare the hemodynamic effects of inhaled prostacyclin and nitric oxide and the administration of i.v. nitroprusside during cardiac surgery with a clinical, pharmacodynamic dose-response, prospective, randomized, and double-blind study (Group A: inhaled prostacyclin; Group B: inhaled nitric oxide; Group C: nitroprusside). Materials and Methods: Fifty…

MaleNitroprussidePulmonary and Respiratory Medicinemedicine.medical_specialtyCardiac outputHypertension Pulmonarymedicine.medical_treatmentProstacyclinNitric OxideNitric oxidechemistry.chemical_compoundMitral valve stenosisDouble-Blind MethodInternal medicineAdministration InhalationmedicineHumansMitral Valve StenosisAntihypertensive AgentsEndothelium-Dependent Relaxing FactorsHeart Valve Prosthesis ImplantationCardiopulmonary Bypassbusiness.industryMitral valve replacementMiddle Agedmedicine.diseaseEpoprostenolPulmonary hypertensionCardiac surgerymedicine.anatomical_structurechemistryAnesthesiacardiovascular systemCardiologyVascular resistanceMitral ValveFemaleSurgeryCardiology and Cardiovascular Medicinebusinessmedicine.drugJournal of Cardiac Surgery
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Associations of rs3918242 and rs2285053 MMP-9 and MMP-2 polymorphisms with the risk, severity, and short- and long-term complications of degenerative…

2016

Abstract Background Degenerative forms of mitral valve diseases (MVDs) are very complex pathologies. Thus, it is difficult to make generalizations about the disease pathways or genetic risk factors contributing to these diseases. However, a key role of metalloproteinases (MMPs) in their pathophysiology is emerging. Thus, we performed for the first time a perspective study to assess eventual associations of some functional single nucleotide polymorphisms (SNPs) in MMP-2 and MMP-9 genes with the MVD risk, symptom severity, and short- and long-term (4.8 years) complications. Materials and methods For this purpose, 90 patients and two control groups were genotyped for rs3918242, rs243865, and r…

MalePathologyHeart Valve DiseasesDisease030204 cardiovascular system & hematologyMatrix metalloproteinasers3918242 rs243865 rs2285053 MMP-2 and MMP-9 gene SNPDegenerative forms of mitral valve diseases; Management and outcome; Metalloproteinases; rs3918242 rs243865 rs2285053 MMP-2 and MMP-9 gene SNPs; Aged; Cohort Studies; Female; Genetic Predisposition to Disease; Genotype; Heart Valve Diseases; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Mitral Valve; Prospective Studies; Risk Factors; Polymorphism Single Nucleotide0403 veterinary scienceCohort Studies0302 clinical mediciners2285053 MMP-2 and MMP-9 gene SNPsRisk FactorsGenotypeManagement and outcomeNatriuretic peptideProspective StudiesProspective cohort studyMVDSMetalloproteinaseDegenerative forms of mitral valve diseases04 agricultural and veterinary sciencesGeneral MedicineSingle NucleotideMiddle AgedMetalloproteinasesPathophysiologyMatrix Metalloproteinase 9Matrix Metalloproteinase 2Mitral ValveFemalers3918242Cardiology and Cardiovascular MedicineDegenerative forms of mitral valve diseasemedicine.medical_specialtyGenotype040301 veterinary sciencesmedicine.drug_class2734Single-nucleotide polymorphismDegenerative forms of mitral valve diseases; Management and outcome; Metalloproteinases; rs3918242 rs243865 rs2285053 MMP-2 and MMP-9 gene SNPs; Cardiology and Cardiovascular Medicine; 2734Polymorphism Single NucleotidePathology and Forensic Medicine03 medical and health sciencesInternal medicinemedicineHumansGenetic Predisposition to Diseasers243865PolymorphismAgedbusiness.industrySettore MED/23 - Chirurgia Cardiacabusiness
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Relocation of Papillary Muscles for Ischemic Mitral Valve Regurgitation

2014

Objective The assessment of the mitral valve apparatus (MVA) and its modifications during ischemic mitral regurgitation (IMR) is better performed by three-dimensional (3D) transesophageal echocardiography (TEE). The aim of our study was to carry out nonrestrictive mitral annuloplasty in addition to relocation of papillary muscles (PPMs) oriented by preoperative real-time 3D TEE through the mitral valve quantification dedicated software. Methods Since January 2008, a total of 70 patients with severe IMR were examined both before and after mitral valve repair. The mean (SD) coaptation depth and the mean (SD) tenting area were 1.4 (0.4) cm and 3.2 (0.5) cm2, respectively. Intraoperative 3D TEE…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyMitral Valve AnnuloplastyMyocardial ischemiamedicine.medical_treatmentTreatment outcomeMyocardial IschemiaEchocardiography Three-DimensionalThree-dimensional echocardiographyPapillary MuscleIschemic mitral valve regurgitationIntraoperative PeriodRetrospective StudieInternal medicineMitral valveMitral valve annuloplastymedicineHumansRetrospective StudiesAgedMitral valve repairIschemic mitral regurgitationbusiness.industryMitral Valve InsufficiencyGeneral MedicinePapillary Musclesmedicine.diseaseFeasibility StudieTreatment Outcomemedicine.anatomical_structureCardiologyFeasibility StudiesFemaleSurgeryIntraoperative PeriodbusinessMitral valve regurgitationCardiology and Cardiovascular MedicineMitral valve repairEchocardiography TransesophagealHumanInnovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
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Impact of moderate ischemic mitral regurgitation after isolated coronary artery bypass grafting

2009

The aim of the study was to evaluate the clinical and echocardiographic outcomes, at rest and under exercise testing, of patients with moderate ischemic mitral regurgitation (IMR) undergoing isolated coronary artery bypass graft surgery (CABG).Between February 2003 and March 2008, 180 patients with moderate IMR who had isolated CABG were enrolled. Patients were matched 1:2 (n = 360) with patients who underwent isolated CABG without IMR (by propensity score). The study endpoints were freedom from all death, cardiac related-death, late events, and cardiac-related events. Late outcomes and left ventricular remodeling were evaluated according to preoperative percent of ejection fraction. Sympto…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtycoronary artery byoass graftingRestmedicine.medical_treatmentMyocardial Ischemiamoderate ischemic mitral regurgitationCoronary Artery DiseaseCoronary artery diseaseInternal medicineMitral valvemedicineHumansMyocardial infarctionCoronary Artery BypassPropensity ScoreVentricular remodelingAgedMitral valve repairMitral regurgitationEjection fractionVentricular Remodelingbusiness.industryMitral Valve InsufficiencyMiddle Agedmedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureEchocardiographyExercise TestCardiologyFemaleSurgeryCardiology and Cardiovascular MedicinebusinessArtery
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Chronic Urticaria After Implantation of a Mitral Annuloplasty Ring in a Nickel-Allergic Patient

2017

MaleReoperationNickel allergymedicine.medical_specialtyMitral Valve AnnuloplastyUrticariaImmunology030204 cardiovascular system & hematologyProsthesis DesignImmunoglobulin E03 medical and health sciences0302 clinical medicineMitral annuloplasty ringDevice removalNickelMitral valve annuloplastyInternal medicineHumansImmunology and AllergyMedicineProsthesis designDevice RemovalChronic urticariaHeart Valve Prosthesis Implantationbiologybusiness.industryMiddle AgedPatch TestsSurgeryChronic diseaseHeart Valve ProsthesisChronic DiseaseDermatitis Allergic ContactCardiologybiology.proteinMitral Valvebusiness030217 neurology & neurosurgeryJournal of Investigational Allergology and Clinical Immunology
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Papillary muscle relocation in conjunction with valve annuloplasty improve repair results in severe ischemic mitral regurgitation

2012

OBJECTIVE: The incidence of recurrent mitral regurgitation (MR) after restrictive annuloplasty (RA) was 5% to 20% in several reports. There are many opinions in favor of adding subvalvular procedures to RA to reduce the tenting forces and improve the repair results. METHODS: From March 2003 to May 2010, 55 patients with severe ischemic MR who had undergone papillary muscle (PPM) relocation in conjunction with mitral annuloplasty in our institutions were enrolled. The patients were matched 1:1 with those who underwent isolated RA using the propensity score. The mean left ventricular ejection fraction was 42% ± 6%. The mean tenting area and coaptation depth was 3.2 ± 0.6 cm(2) and 1.3 ± 0.2 c…

MaleTime FactorsMitral Valve AnnuloplastyLeftMyocardial IschemiaKaplan-Meier EstimateSeverity of Illness IndexVentricular Function LeftPapillary muscle annuloplasty mitral regurgitationPostoperative ComplicationsRisk FactorsMitral valve annuloplastyAged; Chi-Square Distribution; Disease-Free Survival; Female; Hospital Mortality; Humans; Italy; Kaplan-Meier Estimate; Logistic Models; Male; Matched-Pair Analysis; Middle Aged; Mitral Valve Insufficiency; Myocardial Ischemia; Papillary Muscles; Postoperative Complications; Propensity Score; Proportional Hazards Models; Risk Assessment; Risk Factors; Secondary Prevention; Severity of Illness Index; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function Left; Mitral Valve AnnuloplastySecondary PreventionClinical endpointVentricular FunctionHospital MortalityMyocardial infarctionEjection fractionIncidence (epidemiology)Mitral Valve InsufficiencyMiddle AgedPapillary MusclesTreatment Outcomemedicine.anatomical_structureItalyCardiologyFemaleCardiology and Cardiovascular MedicinePulmonary and Respiratory Medicinemedicine.medical_specialtyMatched-Pair AnalysisRisk AssessmentDisease-Free SurvivalInternal medicinemedicineHumansPropensity ScorePapillary muscleAgedProportional Hazards ModelsMitral regurgitationChi-Square Distributionbusiness.industryStroke VolumeSettore MED/23 - Chirurgia Cardiacamedicine.diseaseSurgeryLogistic ModelsPropensity score matchingSurgerybusiness
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Results of mitral valve repair for Barlow disease (bileaflet prolapse) via right minithoracotomy versus conventional median sternotomy: a randomized …

2011

Objective: The results of mitral repair for complex Barlow valves are adequate and support earlier intervention. It is unknown whether these results are reproducible in the context of minimally invasive surgery via right minithoracotomy. Methods: We randomized patients with Barlow mitral disease (bileaflet prolapse) to have conventional open repair via median sternotomy (MS group) or minimally invasive (MI group) repair. Repair was done using polytetrafluoroethylene chordal reimplantation for both leaflets. In the MI group, we adopted right minithoracotomy, peripheral cannulation, external aortic clamping, and surgery under direct vision. Results: Both groups comprised 70 patients. The oper…

MaleTime Factorsmedicine.medical_treatmentKaplan-Meier Estimatelaw.inventionlawRisk FactorsMitral valveCardiac Surgical ProcedureHospital MortalityProspective StudiesUltrasonographyPain PostoperativeMitral Valve ProlapseAtrial fibrillationGenetic Diseases X-LinkedMiddle Agedmedicine.anatomical_structureTreatment OutcomeItalyThoracotomyCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicineHumanPulmonary and Respiratory MedicineAdultReoperationmedicine.medical_specialtyTime FactorContext (language use)Risk AssessmentInternal medicineCardiopulmonary bypassmedicineHumansCardiac Surgical ProceduresMechanical ventilationMitral valve repairMitral regurgitationChi-Square Distributionbusiness.industryRisk FactorPatient SelectionSettore MED/23 - Chirurgia Cardiacamedicine.diseaseSternotomySurgeryProspective StudieMedian sternotomySurgerybusinessThe Journal of thoracic and cardiovascular surgery
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