Search results for "Moda"
showing 10 items of 1753 documents
Recurrence of hepatocellular carcinoma after liver transplantation: an update.
2015
Liver transplantation is the only curative alternative for selected patients with hepatocellular carcinoma (HCC) who are not eligible for resection and/or with decompensated cirrhosis. According to Milan criteria the 5-year survival rate is 70–85%, with a recurrence-free survival of 75%. However, HCC recurrence rate after liver transplantation remains a significant problem in the clinical practice. The prognosis in patients with HCC recurrence is poor. The treatment of choice for HCC recurrence is surgery, but it seems that a systemic treatment based on combination of an mTOR inhibitor with sorafenib can be used. Data on safety and efficacy are limited, clinical monitoring is necessary. Th…
Transarterial chemoembolization and sorafenib in patients with intermediate-stage hepatocellular carcinoma: time to enter routine clinical practice?
2015
According to the guidelines of the European Association for the Study of the Liver (EASL), patients affected from hepatocellular carcinoma (HCC) can be classified according to the Barcelona Clinic Liver Cancer (BCLC) staging system. This classification system divides HCC patients in five stages (0, A, B, C and D) on the basis of a number of prognostic and treatment- related variables such as tumor status and liver function. A specific treat ment approach is then proposed for each of the above-mentioned stages. Transarterial chemoembolization (TACE) is recommended as first-line therapy in the treatment of patients with intermediate-stage (BCLC-B class) HCC [1]. The efficacy of this procedure…
Update on new approaches in the management of hepatocellular carcinoma
2010
Abstract: Hepatocellular carcinoma (HCC) is a major health problem. It is currently the third cause of cancer-related death, it is highly prevalent in the Asia–Pacific region and Africa, and is increasing in Western countries. The natural history of HCC is very heterogeneous and prediction of survival in individual patients is not satisfactory because of the wide spectrum of the disease. During the past decade, major advances have been achieved in prevention, through better surveillance of patients at risk, and in therapy through better surgical and ablative therapies and multimodal treatment approaches. Moreover, the increasing knowledge of molecular hepatocarcinogenesis provides the oppor…
Kropp i bevegelse i bildeboka : Känner du Pippi Långstrump?
2011
In Astrid Lindgren’s authorship, there are many bodies in motion, and one of her most movable and energetic characters is Pippi Longstocking. In the illustrated novels about Pippi (Lindgren and Nyman 1945, 1946, and 1948) there are relatively few pictures, and as a result, Lindgren’s words carry most of the story. In the novels, her words have a greater functional load (Kress 2003, 46 ) than Nyman’s pictures. Naturally then, the words convey most of the information about Pippi and the other characters’ movements. But how does the portrayal of bodies in motion change when Pippi is portrayed in picturebooks where the pictures have a lot more space, ie, a greater functi…
Phenomenological-Semantic Investigations into Incompleteness
2000
When today the phenomenologist surveys the history of the philosophical comprehension of Godel’s theorems, he is confronted with the realization that the decisive publications come almost exclusively from the sphere of analytic philosophy.1 But does phenomenology in the spirit of Husserl not mean to keep in step with the epochal results of the special sciences by working on the phenomenological understanding of them? Phenomenological research of this kind means the same as development of phenomenological theory of science (Wissenschaftstheorie). In connection with the incompleteness theorems, the latter would be confronted with fundamental questions such as, “To what extent can mathematical…
Surgical treatment of solitary sternal metastasis from breast cancer Case report
2016
Bone metastasis is a frequent and early complication of breast cancer. This case report describes a technique for a partial exeresis of the sternum and the reconstruction of the pleura with autologous dermis from the lower abdomen and the loss of substance with a myocutaneous flap.We describe the case of a 50-year old woman with a sternal excavated lesion with pathologic fracture due to an invasive adenocarcinoma, treated with a partial exeresis of the sternum and the reconstruction with a myocutaneous flap.The patient doesn't show evidence of recurrent disease and the stability of her chest well preserved.Metastatic breast cancer to the sternum, if detected early and treated aggressively, …
Motor learning and body size within an insect brain computational model
2014
Nowadays modeling insect brains is also an important source of inspiration to develop learning architectures and control algorithms for applications on autonomous walking robots. Within the insect brain two important neuropiles received a lot of attention: the mushroom bodies (MBs) and the central complex (CX). Recent research activities considered the MBs as a unique architecture where different behavioural functions can be found. MBs are well known in bees and flies for their role in performing associative learning and memory in odor conditioning experiments [4]. They are also involved in the processing of multiple sensory modalities including visual tasks [3], different forms of learning…
Panel Summary:Multistimuli and Different Sensory Modalities
1999
Our everyday environment in which we live is characterised by stimuli capable of eliciting our actions (or reactions). Generally our actions are influenced by a number of stimuli which are multimodal.
Stochastic model of memristor based on the length of conductive region
2021
Abstract We propose a stochastic model of a voltage controlled bipolar memristive system, which includes the properties of widely used dynamic SPICE models and takes into account the fluctuations inherent in memristors. The proposed model is described by rather simple equations of Brownian diffusion, does not require significant computational resources for numerical modeling, and allows obtaining the exact analytical solutions in some cases. The noise-induced transient bimodality phenomenon, arising under resistive switching, was revealed and investigated theoretically and experimentally in a memristive system, by finding a quite good qualitatively agreement between theory and experiment. B…
Strategic Planning for Integrated Mobility-on-Demand and Urban Public Bus Networks
2020
App-based services and ridesharing in the field of mobility-on-demand (MoD) create a new mode of transport between motorized individual transport and public transportation whose long-term role in the urban mobility landscape and within public transport systems is not fully understood as of today. For the public transport industry, these new services offer new chances but also risks, making planning models and tools for integrated intermodal network planning indispensable. We develop a strategic network planning optimization model for bus lines that allows for intermodal trips with MoD as a first or last leg. Starting from an existing public transport network, we decide simultaneously on th…