Search results for "Modality"
showing 10 items of 651 documents
Distance crossing and alignment in online humanitarian discourse
2018
Abstract This article analyzes multimodal genres of current online humanitarian discourse such as mission statements, annual reports and photo galleries to find how the construals of beneficiaries and humanitarian organizations align with the motives, values and emotional dispositions of prospective donors. The discursive reduction of distance between the donor and the beneficiary is likely to produce solicitation effects and enable self-legitimization. First, based on extant literature, the article develops a method to account for the pragmatic operations of textual ‘proximization’ and visually simulated ‘co-presence’ in humanitarian communication. Then it applies it to a sample of multimo…
Language for International Communication: Linking Interdisciplinary Perspectives (2nd international symposium)
2014
This collection contains papers delivered at the 2nd international symposium "Language for International Communication: Linking Interdisciplinary Perspectives" held at the University of Latvia, Latvia, on 23-24 May 2013.
Hepatitis C-related cirrhosis. Current status.
2016
Chronic hepatitis C virus (HCV) infection affects around 150 million people. It is a leading cause of liver related morbidity and mortality through its predisposition to liver fibrosis, cirrhosis and end-stage liver complications. New treatments based on direct-acting antivirals have opened a new era in the management of HCV cirrhosis. They allow for HCV eradication without substantial side effects in almost all cirrhotic patients, reducing the risk of hepatocellular carcinoma, liver decompensation and mortality. This review provides an update on HCV cirrhosis. The paper focuses on the disease burden and major progresses in the diagnosis, follow-up and treatment of this patient subgroup.
Multisciplinary management of patients with liver metastasis from colorectal cancer
2016
Abstract: Colorectal cancer (CRC) is one of the leading causes of cancer-related death. Surgery, radiotherapy and chemotherapy have been till now the main therapeutic strategies for disease control and improvement of the overall survival. Twenty-five per cent (25%) of CRC patients have clinically detectable liver metastases at the initial diagnosis and approximately 50% develop liver metastases during their disease course. Twenty-thirty per cent (20%-30%) are CRC patients with metastases confined to the liver. Some years ago various studies showed a curative potential for liver metastases resection. For this reason some authors proposed the conversion of unresectable liver metastases to res…
[Hemostatic effectiveness of TachoSil® patches in radiofrequency assisted minor hepatic resection].
2011
Aim. Intra- and postoperative bleeding represents an extremely serious and frequent complication of hepatic surgery. The aim of this study was to evaluate the effectiveness of TachoSil (R) to improve hemostasis in radiofrequency assisted minor hepatic resection. Methods. Between July 2008 and June 2010, 31 patients underwent radiofrequency assisted minor hepatic resection. At the end of the liver resection a sponge of TachoSil (R) was applied on the liver. Results. The mean intraoperative bleeding from the liver was 56.1 mL (range 0-300 mL). No patients received intra- and postoperative blood transfusion. Surgical drains were removed between the first and the sixth-eight postoperative day. …
Apprentissage de modalités auxiliaires pour la localisation basée vision
2018
In this paper we present a new training with side modality framework to enhance image-based localization. In order to learn side modality information, we train a fully convo-lutional decoder network that transfers meaningful information from one modality to another. We validate our approach on a challenging urban dataset. Experiments show that our system is able to enhance a purely image-based system by properly learning appearance of a side modality. Compared to state-of-the-art methods, the proposed network is lighter and faster to train, while producing comparable results.
Exploring translation strategies in video game localization
2012
This paper addresses the issue of video game localisation focusing on the different strategies to be used from the point of view of Translation Studies. More precisely, the article explores the possible relation between the translation approaches used in the field and the different genres or textual typologies of video games. As the narrative techniques and the story lines of video games have become more complex and well-developed, the adaptation of games entails a serious challenge for translators. Video games have evolved into multimodal and multidimensional products and new approaches and insights are required when studying the adaptation of games into different cultures. Electronic ente…
Infants' hedonic responsiveness to food odours: a longitudinal study during and after weaning (8, 12 and 22 months)
2013
Abstract Background Olfaction is a highly salient sensory modality in early human life. Neonates show keen olfactory sensitivity and hedonic responsiveness. However, little is known about hedonic olfactory responsiveness between the neonatal period and 2 years of age. In an attempt to fill this gap, this longitudinal follow-up study aimed at investigating hedonic responses to food odours in infants during the first 2 years of life. The second objective was to evaluate whether gender has an influence on hedonic responses during this early period. Four control stimuli and eight odours (four rated by adults as a priori pleasant and four a priori unpleasant) were presented in bottles to 235 inf…
Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors
2014
Abstract: Introduction: Treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) yields tumour responses in non-small cell lung cancer (NSCLC) patients harbouring activating EGFR mutations. However, even in long-lasting responses, resistance to EGFR TKIs invariably occurs. Areas covered: This review examines resistance mechanisms to EGFR TKI treatment, which mainly arise from secondary EGFR mutations. Other resistance-inducing processes include mesenchymal-epithelial transition factor (MET) amplification, epithelial-mesenchymal transformation, phenotypic change from NSCLC to small-cell lung carcinoma, and modifications in parallel signalling pathways. Current…
Emerging drugs for the treatment of vitiligo.
2020
Introduction: Vitiligo is a relatively common autoimmune depigmenting disorder of the skin. There has been a great advance in understanding the pathological basis, which has led to the development and utilization of various new molecules in treating vitiligo. This review aims at a comprehensively describing the treatments available and the emerging treatment aspects and the scope for future developments.Areas covered: This study comprehensively summarizes the current concepts in the pathogenesis of vitiligo with special focus on the cytokine and signaling pathways, which are the targets for newer drugs. JAK kinase signaling pathways and the cytokines involved are the focus of vitiligo treat…