Search results for "Modeling and Simulation"
showing 10 items of 1561 documents
Geographical variation in pharmacological prescription
2009
Promoting rational drug administration in treatments is one of the most important issues in Public Health. Bayesian hierarchical models are a very useful tool for incorporating geographical information into the analysis of pharmacological prescription data. They allow the mapping of spatial components which express the trend of geographical variation. In addition, these models are able to deal with uncertainty in a sequential way through prior distributions on parameters and hyperparameters. Bayes' theorem combines all types of information and provides the posterior distribution which is computed through Markov Chain Monte Carlo (MCMC) simulation methods. Simulated data for pharmacological …
Robust H∞ filtering for networked control systems with markovian jumps and packet dropouts
2014
Published version of an article in the journal: Modeling, Identification and Control. Also available from the publisher at: http://dx.doi.org/10.4173/mic.2014.3.3 Open Access This paper deals with the H∞ filtering problem for uncertain networked control systems. In the study, network-induced delays, limited communication capacity due to signal quantization and packet dropout are all taken into consideration. The finite distributed delays with probability of occurrence in a random way is introduced in the network.The packet dropout is described by a Bernoulli process. The system is modeled as Markovian jumps system with partially known transition probabilities. A full-order filter is designe…
Capacity and Energy-Consumption Optimization for the Cluster-Tree Topology in IEEE 802.15.4
2011
International audience; 802.15.4 proposes to use a cluster-tree hierar- chy to organize the transmissions in Wireless Sensor Networks. In this letter, we propose a framework to analyze formally the capacity and the energy consumption of this structure. We derive a Mixed Integer Linear Programming (MILP) formulation to obtain a topology compliant with the standard. This formulation provides the optimal solution for the network capacity: this con- stitutes an upper bound for any distributed algorithms permitting to construct a cluster-tree. This framework can also be used to evaluate the capacity and to compare quantitatively different cluster-tree algorithms.
Methods for Experimentally Determining Stiffness of a Multi-Axis Machining Centre
2019
This paper deals with global methods for experimentally determining the static stiffness of multi-axis machining centres. Different devices used for measuring deflection, in specific, are explored, where accuracy and usability are highlighted. The methods were tested on a 3-axis CNC milling machine, 2-axis trunnion table and a 6-DOF industrial robot.
Gene connectivity and enzyme evolution in the human metabolic network
2019
[Background] Determining the factors involved in the likelihood of a gene being under adaptive selection is still a challenging goal in Evolutionary Biology. Here, we perform an evolutionary analysis of the human metabolic genes to explore the associations between network structure and the presence and strength of natural selection in the genes whose products are involved in metabolism. Purifying and positive selection are estimated at interspecific (among mammals) and intraspecific (among human populations) levels, and the connections between enzymatic reactions are differentiated between incoming (in-degree) and outgoing (out-degree) links.
The origin of in-plane stresses in axially moving orthotropic continua
2016
In this paper, we address the problem of the origin of in-plane stresses in continuous, two-dimensional high-speed webs. In the case of thin, slender webs, a typical modeling approach is the application of a stationary in-plane model, without considering the effects of the in-plane velocity field. However, for high-speed webs this approach is insufficient, because it neglects the coupling between the total material velocity and the deformation experienced by the material. By using a mixed Lagrange–Euler approach in model derivation, the solid continuum problem can be transformed into a solid continuum flow problem. Mass conservation in the flow problem, and the behaviour of free edges in th…
Assessing the Effect of the Economy for the Common Good System on Business Performance
2023
Extant literature has pointed to organizational hybridity to lever sustainable business transformation. Moreover, some authors hold that there is a possible trade-off between sustainability and performance. However, there is still little empirical evidence on the impact that such sustainability-driven hybridization systems have on performance. Thus, the present study’s main goal is to fill this gap by providing empirical evidence on the impact of the implementation of the Economy for the Common Good, as a sustainability-driven organizational system, on business performance. To do so, the authors relied on a sample of 206 businesses from five European countries. Then, the authors follo…
Decoding the XXI Century’s Marketing Shift: An Agency Theory Framework
2016
Since the beginning of the XXI century, marketing theory has moved through a series of epistemological shifts from modern positivism to postmodern constructivism. This has resulted in a series of changes to the main concepts of “traditional” marketing such as: market, product, customer, and value. These shifts can be better viewed under a social cybernetics approach such as agency theory. This is because there is now a view that the linear concept of value creation needs to give way to the more complex process of value cocreation, where value is created collectively. Agency theory is one approach that is able to shed light on how customers and providers are able to recursively create collec…
Measuring the Change Towards More Sustainable Mobility:MUV Impact Evaluation Approach
2019
Urban areas can be considered the ground for the challenges related to the UN&rsquo
Supplier switching decisions
2007
Abstract In order to maximize profit, a buying firm should continuously search for and access sources which offer more favorable prices. While the literature is replete with works on the formation and development of buyer–supplier relationships, there is surprisingly only scarce research on the termination of such relationships and supplier switching. Using the concept of switching costs in a principal-agent framework, we at first analyze whether a firm switches the entire or a partial quantity to an alternative supplier when there is either symmetric or asymmetric information about the alternative supplier’s cost structure. Information asymmetry results in inert supplier switching decision…