Search results for "Modeling and simulation"
showing 10 items of 1561 documents
Seven Mathematical Models of Hemorrhagic Shock
2021
Although mathematical modelling of pressure-flow dynamics in the cardiocirculatory system has a lengthy history, readily finding the appropriate model for the experimental situation at hand is often a challenge in and of itself. An ideal model would be relatively easy to use and reliable, besides being ethically acceptable. Furthermore, it would address the pathogenic features of the cardiovascular disease that one seeks to investigate. No universally valid model has been identified, even though a host of models have been developed. The object of this review is to describe several of the most relevant mathematical models of the cardiovascular system: the physiological features of circulator…
Reverse-engineering post-transcriptional regulation of gap genes in Drosophila melanogaster
2013
16 páginas, 6 figuras, 1 tabla
Knowledge-based modelling applied to synucleinopathies
2015
International audience; The adoption of telemedicine technologies has enabled collaborative programs involving a variety of links among distributed medical structures and health officials and professionals. The use for telemedicine for transmission of medical data and the possibility for several distant physicians to share their knowledge on given medical cases provides clear benefits, but also raises several unsolved conceptual and technical challenges. The seamless exchange and access of medical information between medical structures, health professionals, and patients is a prerequisite for the harmonious development of this new medical practice. This paper proposes a new approach of sema…
Dynamical amplification of electric polarization through nonlinear phononics in 2D SnTe
2020
Ultrafast optical control of ferroelectricity using intense terahertz fields has attracted significant interest. Here we show that the nonlinear interactions between two optical phonons in SnTe, a two-dimensional in-plane ferroelectric material, enables a dynamical amplification of the electric polarization within subpicoseconds time domain. Our first-principles time-dependent simulations show that the infrared-active out-of-plane phonon mode, pumped to nonlinear regimes, spontaneously generates in-plane motions, leading to rectified oscillations in the in-plane electric polarization. We suggest that this dynamical control of ferroelectric material, by nonlinear phonon excitation, can be ut…
Tabu search for the dynamic Bipartite Drawing Problem
2018
Abstract Drawings of graphs have many applications and they are nowadays well-established tools in computer science in general, and optimization in particular. Project scheduling is one of the many areas in which representation of graphs constitutes an important instrument. The experience shows that the main quality desired for drawings of graphs is readability, and crossing reduction is a fundamental aesthetic criterion to achieve it. Incremental or dynamic graph drawing is an emerging topic in this context, where we seek to preserve the layout of a graph over successive drawings. In this paper, we target the edge crossing reduction in the context of incremental graph drawing. Specifically…
On enhancing the object migration automaton using the Pursuit paradigm
2017
Abstract One of the most difficult problems that is all-pervasive in computing is that of partitioning. It has applications in the partitioning of databases into relations, the realization of the relations themselves into sub-relations based on the partitioning of the attributes, the assignment of processes to processors, graph partitioning, and the task assignment problem, etc. The problem is known to be NP-hard. The benchmark solution for this for the Equi-Partitioning Problem (EPP) has involved the classic field of Learning Automata (LA), and the corresponding algorithm, the Object Migrating Automata (OMA) has been used in all of these application domains. While the OMA is a fixed struct…
nalysis, Modeling and Simulation of Mechatronic Systems using the Bond Graph Method
2011
The Bond Graph is the proper choice of physical system used for: (i) Modeling which can be applied to systems combining multidisciplinary energy domains, (ii) Analysis to provide a great value proposition for finding the algebraic loops within the system enabling the process of troubleshooting and eliminating the defects by using the proper component(s) to fix the causality conflict even without being acquainted in the proper system, and (iii) Simulation facilitated through derived state space equations from the Bond Graph model is solved using industrial simulation software, such as 20-Sim. The Bond Graph technique is a graphical language of modeling, in which component energy ports are co…
Heuristics for the Constrained Incremental Graph Drawing Problem
2019
Abstract Visualization of information is a relevant topic in Computer Science, where graphs have become a standard representation model, and graph drawing is now a well-established area. Within this context, edge crossing minimization is a widely studied problem given its importance in obtaining readable representations of graphs. In this paper, we focus on the so-called incremental graph drawing problem, in which we try to preserve the user’s mental map when obtaining successive drawings of the same graph. In particular, we minimize the number of edge crossings while satisfying some constraints required to preserve the position of vertices with respect to previous drawings. We propose heur…
GPU-accelerated exhaustive search for third-order epistatic interactions in case–control studies
2015
This is a post-peer-review, pre-copyedit version of an article published in Journal of Computational Science. The final authenticated version is available online at: https://doi.org/10.1016/j.jocs.2015.04.001 [Abstract] Interest in discovering combinations of genetic markers from case–control studies, such as Genome Wide Association Studies (GWAS), that are strongly associated to diseases has increased in recent years. Detecting epistasis, i.e. interactions among k markers (k ≥ 2), is an important but time consuming operation since statistical computations have to be performed for each k-tuple of measured markers. Efficient exhaustive methods have been proposed for k = 2, but exhaustive thi…
Diagrammatic approach to cellular automata and the emergence of form with inner structure
2018
We present a diagrammatic method to build up sophisticated cellular automata (CAs) as models of complex physical systems. The diagrams complement the mathematical approach to CA modeling, whose details are also presented here, and allow CAs in rule space to be classified according to their hierarchy of layers. Since the method is valid for any discrete operator and only depends on the alphabet size, the resulting conclusions, of general validity, apply to CAs in any dimension or order in time, arbitrary neighborhood ranges and topology. We provide several examples of the method, illustrating how it can be applied to the mathematical modeling of the emergence of order out of disorder. Specif…