Search results for "Modeling and simulation"
showing 10 items of 1561 documents
Distributed Consensus in Noncooperative Inventory Games
2009
This paper deals with repeated nonsymmetric congestion games in which the players cannot observe their payoffs at each stage. Examples of applications come from sharing facilities by multiple users. We show that these games present a unique Pareto optimal Nash equilibrium that dominates all other Nash equilibria and consequently it is also the social optimum among all equilibria, as it minimizes the sum of all the players’ costs. We assume that the players adopt a best response strategy. At each stage, they construct their belief concerning others probable behavior, and then, simultaneously make a decision by optimizing their payoff based on their beliefs. Within this context, we provide a …
Multiobjective GRASP with Path Relinking
2015
In this paper we review and propose different adaptations of the GRASP metaheuristic to solve multiobjective combinatorial optimization problems. In particular, we describe several alternatives to specialize the construction and improvement components of GRASP when two or more objectives are considered. GRASP has been successfully coupled with Path Relinking for single-objective optimization. Moreover, we propose different hybridizations of GRASP and Path Relinking for multiobjective optimization. We apply the proposed GRASP with Path Relinking variants to two combinatorial optimization problems, the biobjective orienteering problem and the biobjective path dissimilarity problem. We report …
Finite-size effects of Kirkwood–Buff integrals from molecular simulations
2017
The modelling of thermodynamic properties of liquids from local density fluctuations is relevant to many chemical and biological processes. The Kirkwood–Buff (KB) theory connects the microscopic structure of isotropic liquids with macroscopic properties such as partial derivatives of activity coefficients, partial molar volumes and compressibilities. Originally, KB integrals were formulated for open and infinite systems which are difficult to access with standard Molecular Dynamics (MD) simulations. Recently, KB integrals for finite and open systems were formulated (J Phys Chem Lett. 2013;4:235). From the scaling of KB integrals for finite subvolumes, embedded in larger reservoirs, with the…
Inter-Model Consistency and Complementarity: Learning from ex-vivo Imaging and Electrophysiological Data towards an Integrated Understanding of Cardi…
2011
International audience; Computational models of the heart at various scales and levels of complexity have been independently developed, parameterised and validated using a wide range of experimental data for over four decades. However, despite remarkable progress, the lack of coordinated efforts to compare and combine these computational models has limited their impact on the numerous open questions in cardiac physiology. To address this issue, a comprehensive dataset has previously been made available to the community that contains the cardiac anatomy and fibre orientations from magnetic resonance imaging as well as epicardial transmembrane potentials from optical mapping measured on a per…
Robust dynamical pattern formation from a multifunctional minimal genetic circuit.
2010
Abstract Background A practical problem during the analysis of natural networks is their complexity, thus the use of synthetic circuits would allow to unveil the natural mechanisms of operation. Autocatalytic gene regulatory networks play an important role in shaping the development of multicellular organisms, whereas oscillatory circuits are used to control gene expression under variable environments such as the light-dark cycle. Results We propose a new mechanism to generate developmental patterns and oscillations using a minimal number of genes. For this, we design a synthetic gene circuit with an antagonistic self-regulation to study the spatio-temporal control of protein expression. He…
Analytically solvable Hamiltonians for quantum two-level systems and their dynamics
2014
A simple systematic way of obtaining analytically solvable Hamiltonians for quantum two-level systems is presented. In this method, a time-dependent Hamiltonian and the resulting unitary evolution operator are connected through an arbitrary function of time, furnishing us with new analytically solvable cases. The method is surprisingly simple, direct, and transparent and is applicable to a wide class of two-level Hamiltonians with no involved constraint on the input function. A few examples illustrate how the method leads to simple solvable Hamiltonians and dynamics.
Variational formulations and extra boundary conditions within stress gradient elasticity theory with extensions to beam and plate models
2016
Abstract The principle of minimum total potential energy and the primary principle of virtual power for stress gradient elasticity are presented as kinematic type constructs dual of analogous static type principles from the literature (Polizzotto, 2014; Polizzotto, 2015a). The extra gradient-induced boundary conditions are formulated as “boundary congruence conditions” on the microstructure’s deformation relative to the continuum, which ultimately require that the normal derivative of the stresses must vanish at the boundary surface. Two forms of the governing PDEs for the relevant boundary-value problem are presented and their computational aspects are discussed. The Timoshenko beam and th…
Fractional viscoelastic beam under torsion
2017
Abstract This paper introduces a study on twisted viscoelastic beams, having considered fractional calculus to capture the viscoelastic behaviour. Further another novelty of this paper is extending a recent numerical approach, labelled line elementless method (LEM), to viscoelastic beams. The latter does not require any discretization neither in the domain nor in the boundary. Some numerical applications have been reported to demonstrate the efficiency and accuracy of the method.
LEM for twisted re-entrant angle sections
2014
In this paper an innovative numerical method named as line element-less method, LEM, for finding solution of torsion problem has been extended to all shaped sections, including sections possessing re-entrant angles at their boundary. The response solution in terms of shear stress field or Prandtl function or warping function in all domain and for any kind of domain with arbitrary contour, may be performed quickly, calculating line integrals only. The method takes full advantage of the theory of analytic complex function and is robust in the sense that returns exact solution if this exists. Numerical implementation of LEM has been developed using Mathematica software without resorting to any…
Capacity-based calculation of passenger car equivalents using traffic simulation at double-lane roundabouts
2018
Abstract Calculation of passenger car equivalents for heavy vehicles represents the starting point for the operational analysis of road facilities and other traffic management applications. This paper introduces a criterion to find the passenger car equivalents that reflect traffic conditions at double-lane roundabouts, where the capacity is typically estimated for each entry lane. Based on the equivalence defined by the proportion of capacity used by vehicles of different classes, the criterion implies a comparison between the capacity that would occur with a traffic demand of passenger cars only and the capacity reached beginning from a demand with a certain percentage of heavy vehicles. …