Search results for "Modeling"
showing 10 items of 4489 documents
Quality evaluation in public services: statistical modelling for effective management.
1999
Classical and reverse substituent effects in meta- and para-substituted nitrobenzene derivatives
2017
Electron-accepting properties of the nitro group were studied in a series of meta- and para-X-substituted nitrobenzene derivatives (X = NMe2, NH2, OH, OMe, CH3, H, F, Cl, CF3, CN, CHO, COMe, CONH2, COOH, COCl, NO2, NO). For this purpose Hammett-like approaches were applied based on quantum chemistry modeling; the B3LYP/6-311++ G(d,p) method was used. The substituent effect (SE) was characterized by the mutually interrelated descriptors: the charge of the substituent active region, cSAR(X), and substituent effect stabilization energy, SESE, as well as substituent constants, σ. Classical SE is realized by dependences of the structural parameters of the nitro group (ONO angle and NO bond lengt…
Sulfonamide moiety as "molecular chimera" in the design of new drugs.
2021
Background: The -SO2NH- group is of great significance in modern pharmaceutical use since, in sulfa-drugs, it is possible to introduce easily chemical modifications, and even small changes may lead to an improved version of an already existing drug. Objective: This paper aims to describe updated information in the sulfonamide field with a particular focus on new mechanisms of action, especially if discovered by employing computational approaches. Methods: Research articles that focused on the use of the sulfonamide moiety for the design, synthesis, and in vitro/in vivo tests of various diseases were collected from various search engines like PubMed, Science Direct, Google Scholar, and Scop…
Maturity of Supply Chain as a Factor of Modeling the Relationships with Suppliers
2017
The following paper will discuss the level of maturity of the supply chain as a main factor that determines supplier relationships in the supply chain. The Ch. C. Piorier categorization was taken into consideration, where the development of supply chains includes 5 stages. Analysis of individual stages of supply chain maturity towards presented classification is a substitute for identifying different models of supplier relationships in the supply chain. In the supply chain, supplier relationships are established in order to enter into a partnership. Establishing relationships with suppliers in the supply chain appears to create by a stronger partnership. The capability of this cooperation d…
A multifractal approach of central place theory for sustainable planning
2013
International audience
DEVELOPMENT OF SUSTAINABLE METROPOLITAN AREAS USING A MULTI-SCALE DECISION SUPPORT SYSTEM
2012
A sustainable and sustaining planning strategy is globally important for metropolitan areas. Sustainable planning addresses the development of strategies to reduce the use of resources, increase economic efficiency and improve integration of social aspects. In contrast, splinter development (e.g. urban sprawl) involves damage to nature and generation of an increasing volume of traffic (these are the main criticisms following a study by Newman and Kenworthy (1989) on the relationship between settlement density and energy consumption). Interestingly, the overly compact city also has this effect as it may generate traffic flows for accessing green and leisure areas, or changes of residence due…
Анализ проблем развития лесопромышленного комплекса при формировании модели экономики замкнутого цикла на примере Томской области
2019
The main objective of the paper is the conduction of the timber industry complex problems analysis from the circular economy and sustainable development point of view. The problem of waste is considered in conjunction with other environmental, economic and social problems. A modeling of the value chain process and the formation of threats along the whole chain «nature (forest) – economy – society (consumer)» is being conducted. A classification of the development problems in the timber industry complex on the basis of «created values» and «production factors» has been developed. Planned growth in logging volume and wood processing, expansion of unused waste require the development of a spec…
Stratégie d'aménagement pour le développement durable d'aires métropolitaines par un système multi-scalaire d'aide à la décision : l'exemple de Vienne
2012
A sustainable and sustaining planning strategy is globally important for metropolitan areas. Sustainable planning addresses the development of strategies to reduce the use of resources, increase economic efficiency and improve integration of social aspects (e.g. pedestrian-friendly environments, well-balanced public and private transport modes, efficient street networks, land use, movement economy; access for all to jobs, retail, services; healthcare, culture and leisure). In contrast, splinter development (e.g. urban sprawl) involves damage to nature and generation of an increasing volume of traffic (these are the main criticisms following a study by Newman and Kenworthy (1989) on the rela…
A Research Agenda for Evaluating Strength of Internal Preferences and External Influences in Consumer Smartphone Switching
2015
This article proposes a research agenda to study what causes consumers to switch smartphone manufacturer and operating system brands. International consumer survey is planned for data collection and structural equation modeling method will be used to extrapolate whether internal preferences play a larger role than external influences in consumers’ switching behavior. The effects are expected to be moderated by behavioral control, subjective uncertainty and prior switching experience and controlled with a set of constraint variables. As a theoretical contribution, we propose a new theory to evaluate switching primarily through the latent construct of magnitude of switch. Potential practical …
The Impact of Financial Development and Macroeconomic Fundamentals on Nonperforming Loans among Emerging Countries: An Assessment Using the NARDL App…
2022
The relationship between financial development indicators and non-performing loans (NPLs) has garnered significant attention, especially in emerging countries. The puzzle of whether financial sector development increases or decreases Non-performing Loans (NPL)s has not been resolved to the satisfaction of the curious mind. This research attempts to answer the above question by studying the asymmetric and symmetric association between financial sector development and NPLs, by utilizing the novel non-linear autoregressive distribution lag (NARDL) and the linear autoregressive distribution lag (ARDL) approach. Moreover, to make the study inclusive, we have added a series of proxies to measure …