Search results for "Modula"

showing 10 items of 1481 documents

Tyramine Actions on Drosophila Flight Behavior Are Affected by a Glial Dehydrogenase/Reductase

2017

The biogenic amines octopamine (OA) and tyramine (TA) modulate insect motor behavior in an antagonistic manner. OA generally enhances locomotor behaviors such as Drosophila larval crawling and flight, whereas TA decreases locomotor activity. However, the mechanisms and cellular targets of TA modulation of locomotor activity are incompletely understood. This study combines immunocytochemistry, genetics and flight behavioral assays in the Drosophila model system to test the role of a candidate enzyme for TA catabolism, named Nazgul (Naz), in flight motor behavioral control. We hypothesize that the dehydrogenase/reductase Naz represents a critical step in TA catabolism. Immunocytochemistry rev…

gliaCognitive NeuroscienceNeuroscience (miscellaneous)tyraminelcsh:RC321-571570 Life sciencesflightmodulationCellular and Molecular Neurosciencebiogenic amineDevelopmental NeuroscienceDrosophilalcsh:Neurosciences. Biological psychiatry. Neuropsychiatry570 BiowissenschaftenFrontiers in Systems Neuroscience
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INVOLVEMENT OF GUANINE-BASED PURINES IN THE MODULATION OF CHOLINERGIC TRANSMISSION IN MOUSE COLONIC PREPARATIONS

2010

guanine based purinemouse coloncholinergic transmission neuromodulation
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Long-term follow-up of hepatitis B e antigen-negative patients treated with peginterferon α-2a: progressive decrease in hepatitis B surface antigen i…

2012

hepatitis B virus therapy immunomodulator nucleos(t)ide analogues quantitative hepatitis B surface antigen
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Wharton’s jelly mesenchymal stem cells differentiation into hepatocyte-like cells: functional characterization and expression of immunomodulatory mol…

2015

Mesenchymal stem cells derived from Wharton’s jelly (WJ-MSCs) recently emerged as promising tools for cellular therapy due to their ability to differentiate into diverse cell types and their immunomodulatory features. Little is known on the expression of immunomodulatory molecules in mature cells differentiated from WJ-MSCs, therefore we aimed to characterize the extent of maintenance of the naive traits of these cells also in a highly specialized differentiated counterpart. WJ-MSCs were differentiated into hepatocyte-like cells (HLCs) with a four weeks protocol. RT-PCR, flow cytometry, IHC and ICC were performed to assess expression of key markers in both undifferentiated and differentiate…

hepatocyte differentiationmesenchymal stem cellsimmune modulationUmbilical cord; perinatal stem cells; mesenchymal stem cells; hepatocyte differentiation; immune modulation.Settore BIO/16 - Anatomia UmanaWharton's jellyperinatal stem cellcell therapyUmbilical cordliver
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At the roots of tolerogenicity and immune modulation: an in vitro and in situ survey on the expression of immunomodulatory molecules by Wharton’s jel…

2012

immune modulationSettore BIO/16 - Anatomia Umanatolerogenicityimmunomodulatory moleculeWharton’s jelly mesenchymal stem cells
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Uz hialuronskābes bāzes veidotu funkcionalizētu biomateriālu efektivitātes un drošības izvērtējums in vivo diabēta brūču modelī

2016

Hronisko brūču dzīšana ir viena no aktuālākajām tēmām medicīnas nozarē, un tādēļ ir nepieciešams izstrādāt jaunus materiālus un aktīvās vielas, kuri būtu efektīvāki un ātrāki hronisko brūču aprūpes risinājumos. Maģistra darbā tika izvērtēti jaunizveidotie biomateriāli, kas ietver glikoproteīnu, efektivitāte brūču dzīšanas procesos Wistar žurku tēviņiem un veikti akūtas toksicitātes noteikšanas pētījumi ICR peļu tēviņiem. Iegūtie rezultāti diabētisko brūču dzīšanas procesā parāda, ka jau sākot ar pētījuma otro dienu, salīdzinot ar kontroles grupu, diviem jaunizveidotiem biomateriāliem ir progresīva un efektīva diabētisko brūču dzīšana. Dabīgais immunomodulators uzrādīja drošus rezultātus aku…

imunomodulatoriFarmācijadiabētisko brūču dzīšanaglikoproteīniin vivo diabēta brūču modeļi
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Uz hialuronskābes bāzes veidotu funkcionalizētu biomateriālu efektivitātes un drošības izvērtējums in vivo brūču modelī

2015

Joprojām ir aktuāla dzīšanu stimulējošu, jaunu funkcionālu biomateriālu izveide, lai nodrošinātu ātrāku un efektīvāku brūču dzīšanas procesu klīnikā. Maģistra darbā tika izvērtēti jaunizveidotie biomateriāli, kas ietver glikoproteīnu, efektivitāte brūču dzīšanas procesos Wistar žurku tēviņiem un veikti akūtas toksicitātes noteikšanas pētījumi C57BL/6 līnijas peļu tēviņiem. Iegūtie rezultāti uz brūču dzīšanas procesu apstiprina jaunizveidoto biomateriālu (1 un 2) efektivitāti un progresīvu dinamiku brūču dzīšanas procesos, jau sākot ar pētījuma ceturto dienu, salīdzinot ar kontroles grupas rezultātiem. Pēc lielu devu intraperitoneālas ievadīšanas dabīgais imunomodulators uzrāda drošību akūta…

in vivo brūču modeļiimunomodulatoribrūču dzīšanaFarmācijaglikoproteīni
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DA-Phen, a new dopamine aminoacid conjugate: in vivo testing and molecular modeling as dopaminergic modulator

2014

in vivo testingDopaminergic modulatormolecular modelingSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoSettore BIO/14 - FarmacologiaSettore CHIM/08 - Chimica Farmaceuticaaminoacid conjiugate
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Octave Spanning Supercontinuum in Titanium Dioxide Waveguides

2018

International audience; We report on the experimental generation of an octave-spanning supercontinuum in a 2.2 cm-long titanium dioxide optical waveguide with two zero dispersion wavelengths. The resulting on-chip supercontinuum reaches the visible wavelength range as well as the mid-infrared region by using a femtosecond fiber laser pump at 1.64 µm.

integrated optics; supercontinuum generation; titanium dioxidePhysics::Optics02 engineering and technologyFemtosecond fiber laser01 natural sciences7. Clean energylcsh:Technologylaw.inventionlcsh:Chemistrychemistry.chemical_compoundlawDispersion (optics)General Materials ScienceInstrumentationlcsh:QH301-705.5ComputingMilieux_MISCELLANEOUSFluid Flow and Transfer Processes[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics][ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]General Engineering021001 nanoscience & nanotechnologylcsh:QC1-999Computer Science ApplicationsWavelengthintegrated opticsFemtosecondOptoelectronicsIntegrated optics0210 nano-technologyVisible spectrum[PHYS.PHYS.PHYS-OPTICS] Physics [physics]/Physics [physics]/Optics [physics.optics]Materials scienceAstrophysics::Cosmology and Extragalactic AstrophysicsOctave (electronics)010309 optics0103 physical sciencesSelf-phase modulationsupercontinuum generationbusiness.industrytitanium dioxidelcsh:TProcess Chemistry and TechnologyLaserSupercontinuumchemistrylcsh:Biology (General)lcsh:QD1-999lcsh:TA1-2040Titanium dioxidebusinesslcsh:Engineering (General). Civil engineering (General)Refractive indexlcsh:PhysicsApplied Sciences
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Design and Realization of a Bidirectional Full Bridge Converter with Improved Modulation Strategies

2020

In this paper a Full-Bridge Converter (FBC) for bidirectional power transfer is presented. The proposed FBC is an isolated DC-DC bidirectional converter, connected to a double voltage source&mdash

isolated DC-DC bidirectional converterComputer Networks and CommunicationsComputer science020209 energylcsh:TK7800-836002 engineering and technologySettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettrici7. Clean energySettore ING-INF/01 - Elettronicafull-bridge converterlaw.inventionFull bridge converterlaw0202 electrical engineering electronic engineering information engineeringElectronic engineeringMaximum power transfer theoremElectrical and Electronic EngineeringTransformerfull-bridge converter; isolated DC-DC bidirectional converter; phase shift modulation; supercapacitorssupercapacitors020208 electrical & electronic engineeringlcsh:Electronicsphase shift modulationHardware and ArchitectureControl and Systems EngineeringSignal ProcessingVoltageElectronics
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