Search results for "Moi"

showing 10 items of 2109 documents

Investigation of the elastic and inelastic scattering of 4He from 11B in the energy range 29-50.5 MeV

2018

We have measured the angular distributions for the elastic and inelastic scattering of 4He from 11B in the isochronous cyclotron U-150 M INP RK. The extracted α-particles beam has been accelerated to energy 29 MeV and then directed to 11B target. The experimental results were analyzed within the framework of both the optical model using different complex potential and the double folding potential obtained with different density-dependent NN interactions which give the corresponding values of the nuclear incompressibility K in the Hartree-Fock calculation of nuclear matter. peerReviewed

syklotronitNuclear Theoryscattering (physics)sirontaelasticityydinfysiikkacyclotronskimmoisuus
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Helsingin osa-alueiden työvoimatilastojen estimointi pienaluetekniikalla valtakunnallisesta työvoimatutkimuksesta

1997

synteettinen estimaattorikomposiittiestimaattorismall area estimationsmall areapienalue-estimointityöttömättyövoimasynthetic estimatorpienaluetyölliset
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Fluorinated heterocyclic compounds: an assay on the photochemistry of some fluorinated 1-oxa-2-azoles: an expedient route to fluorinated heterocycles

2004

Abstract Photoinduced heterocyclic rearrangements of ON bond-containing azoles have been claimed in the synthesis of target fluorinated heterocyclic compounds. In this context, the photochemical behavior of some fluorinated 1,2,4-oxadiazoles has been investigated. Irradiations of 3-amino-5-perfluoroalkyl-1,2,4-oxadiazoles at λ =313 nm in methanol gave open-chain products arising from a reaction of the nucleophilic solvent with either the first formed ring-photolytic species or with a nitrilimine moiety generated from it. Differently, irradiations in methanol with the presence of triethylamine (TEA) followed competing phototransposition pathways leading to the ring-isomers 2-amino-5-perfluo…

synthesisFluorinated heterocyclic compounds Oxadiazoles Synthesis Photochemistry Molecular rearrangementsfluorinated heterocyclic compounds;oxadiazoles;synthesis;photochemistry;molecular rearrangementsmolecular rearrangementsContext (language use)PhotochemistryBiochemistryInorganic Chemistrychemistry.chemical_compoundNucleophileEnvironmental ChemistryMoietySettore CHIM/01 - Chimica AnaliticaPhysical and Theoretical ChemistryTriethylaminephotochemistryNitrilimineOrganic ChemistryoxadiazolesSettore CHIM/06 - Chimica OrganicaGeneral MedicineSolventchemistryfluorinated heterocyclic compoundsMethanolSolvolysis
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Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety

2019

σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and pharmacologically evaluated. In structure-activity relationships studies, the σ1 receptor affinity and σ1:σ2 selectivity were correlated with the stereochemistry, the kind and substitution pattern of the O-heterocycle, and the substituents at the exocyclic amino moiety. cis-configured 2-benzopyran cis-11b bearing a methoxy group and a tertiary cyclohexylmethylamino moiety showed the highest σ1 affinity ( Ki = 1.9 nM) of this series of compounds. In…

synthesisexocyclic amino moietyReceptors Opioid mudocking studieCrystallography X-RayLigands01 natural sciencesopioid receptorschemistry.chemical_compoundProtein structureDrug DiscoveryMoiety0303 health sciencesσ1 receptor ligandsstructure (σ1) affinity relationshipmolecular dynamicBenzyl groupMolecular MedicinesynthesiBenzopyransSelectivityHydrophobic and Hydrophilic Interactionsfree binding enthalpyStereochemistrychange of receptor profileMolecular Dynamics Simulation03 medical and health sciencesStructure-Activity Relationshipσ1 receptor ligands; spirocyclic compounds; benzopyrans; benzofurans; exocyclic amino moiety; synthesis; structure (σ1) affinity relationships; σ1 antagonistic activity; receptor selectivity; molecular dynamics; docking studies; free binding enthalpy; X-ray crystal structure; opioid receptors; MOR affinity; change of receptor profile; structure MOR affinity relationshipsstructure (σ1) affinity relationshipsStructure–activity relationshipHumansReceptors sigmaBenzopyransSpiro Compoundsspirocyclic compoundBinding siteMOR affinity030304 developmental biologybenzopyranbenzofuransσ1 receptor ligandBinding Sitesspirocyclic compoundsreceptor selectivitystructure MOR affinity relationshipsdocking studiesbenzofuranopioid receptorX-ray crystal structuremolecular dynamics0104 chemical sciencesProtein Structure Tertiary010404 medicinal & biomolecular chemistrychemistrySalt bridgeσ1 antagonistic activity
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Rossiâ - Polʹša: nesovpadenie pamâtej. Lingvističeskij aspekt

2017

„Memory turn” in the humanities allows to approach old problems from a new perspective. The author argues that the sphere of complicated Russian-Polish relations should be presented as a conflict between two distinct collective memories. The author considers “memory” as strictly interconnected with so called “non-memory” (i.e. as set of facts not related to memory or superseded by it). In principle, collective memory / non-memory can be subjected to linguistic analysis because it is verbalized and therefore it has its different verbal exponents. The author refers back to his concept of “mental geography” developed 20 years ago and argues that a multi-stage process of mapping two national me…

synthetic definitionverbalizationcollective memorylieux de mémoiremappingproper names
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Sähkömagneettisen sironnan numeerinen simulointi

2004

sähkömagnetismiMaxwellin yhtälötsimulointiapproksimointi
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A variational inequality approach to constrained control problems

1986

säätöteorianumeeriset menetelmätvariaatiolaskentamatemaattinen optimointiepäyhtälöt
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Surrogate-assisted evolutionary multiobjective shape optimization of an air intake ventilation system

2017

We tackle three different challenges in solving a real-world industrial problem: formulating the optimization problem, connecting different simulation tools and dealing with computationally expensive objective functions. The problem to be optimized is an air intake ventilation system of a tractor and consists of three computationally expensive objective functions. We describe the modeling of the system and its numerical evaluation with a commercial software. To obtain solutions in few function evaluations, a recently proposed surrogate-assisted evolutionary algorithm K-RVEA is applied. The diameters of four different outlets of the ventilation system are considered as decision variables. Fr…

ta1130209 industrial biotechnologyMathematical optimizationnumerical modelsOptimization problemlineaarinen optimointiLinear programmingComputer sciencesoftwarehydraulijärjestelmätventilationEvolutionary algorithmlinear programming02 engineering and technologyFunction (mathematics)Set (abstract data type)resistance020901 industrial engineering & automationhydraulic systemsilmanvaihto0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingShape optimizationoptimization
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Exact extension of the DIRECT algorithm to multiple objectives

2019

The direct algorithm has been recognized as an efficient global optimization method which has few requirements of regularity and has proven to be globally convergent in general cases. direct has been an inspiration or has been used as a component for many multiobjective optimization algorithms. We propose an exact and as genuine as possible extension of the direct method for multiple objectives, providing a proof of global convergence (i.e., a guarantee that in an infinite time the algorithm becomes everywhere dense). We test the efficiency of the algorithm on a nonlinear and nonconvex vector function. peerReviewed

ta113Computer scienceDirect methodta111multi-objective optimisationExtension (predicate logic)algorithmsMulti-objective optimizationmonitavoiteoptimointiNonlinear systemComponent (UML)Convergence (routing)algoritmitGlobal optimizationVector-valued functionAlgorithm
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LOCAL CONTROL OF SOUND IN STOCHASTIC DOMAINS BASED ON FINITE ELEMENT MODELS

2011

A numerical method for optimizing the local control of sound in a stochastic domain is developed. A three-dimensional enclosed acoustic space, for example, a cabin with acoustic actuators in given locations is modeled using the finite element method in the frequency domain. The optimal local noise control signals minimizing the least square of the pressure field in the silent region are given by the solution of a quadratic optimization problem. The developed method computes a robust local noise control in the presence of randomly varying parameters such as variations in the acoustic space. Numerical examples consider the noise experienced by a vehicle driver with a varying posture. In a mod…

ta113Stochastic domainAcoustics and UltrasonicsComputer scienceApplied MathematicsAcousticsNoise reductionNumerical analysisstokastinen aluekvadraattinen optimointipassenger carFinite element methodhenkilöautoelementtimenetelmäAcoustic spacequadratic optimizationNoiseFrequency domainNoise controlHelmholtz equationQuadratic programmingpaikallinen äänenhallintaäärellisten elementtien menetelmäHelmholtzin yhtälölocal sound controlJournal of Computational Acoustics
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