Search results for "Moi"

showing 10 items of 2109 documents

Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.

1998

We have synthesized analogues of two naturally occurring antiinflammatory marine compounds, manoalide and cacospongionolide B, containing a pyranofuranone moiety which is considered the pharmacophoric group. The two compounds, and hence their analogues, differ in the presence or absence in the dihydropyran ring of an hemiacetal function which was considered essential to irreversibly inactivate phospholipase A 2 (PLA 2 ). The two series of compounds were tested for their inhibitory effects on secretory PLA 2 belonging to the groups I, II, and III, and the activities were found to be similar in both series, irrespective of the presence or absence of the additional hemiacetal function. In addi…

DihydropyranStereochemistrySwineCarrageenanChemical synthesisPhospholipases ACell Linechemistry.chemical_compoundManoalideMiceStructure-Activity RelationshipCytosol4-ButyrolactoneDrug DiscoveryMoietyAnimalsEdemaHumansEnzyme InhibitorsPancreasPyranschemistry.chemical_classificationElapid VenomsPhospholipase AbiologyMolecular StructureTerpenesAnti-Inflammatory Agents Non-SteroidalSynovial MembraneBee VenomsKineticsPhospholipases A2chemistryEnzyme inhibitorDrug Designbiology.proteinMolecular MedicineHemiacetalFemaleLactoneJournal of medicinal chemistry
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La création du patrimoine artistique dijonnais pendant la Révolution par l’inventaire de François Devosge : collections et institutions

2019

National audience

Dijon[SHS.ART]Humanities and Social Sciences/Art and art history[SHS.MUSEO]Humanities and Social Sciences/Cultural heritage and museologyRévolutionculture[SHS.MUSEO] Humanities and Social Sciences/Cultural heritage and museologyinventairepatrimoineBourgogne[SHS.ART] Humanities and Social Sciences/Art and art historyFrançois DevosgemuséeComputingMilieux_MISCELLANEOUSart
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ChemInform Abstract: Regiospecific and Stereoselective Ene Reaction of the A-Ring Methylcyclohexene Moiety of Polycyclic Terpenoid Systems with Dimet…

2010

Dimethyl acetylenedicarboxylateTerpenechemistry.chemical_compoundchemistryStereochemistryMoietyStereoselectivityGeneral MedicineRing (chemistry)Ene reactionTerpenoidChemInform
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Regiospecific and stereoselective ene reaction of the A-ring methylcyclohexene moiety of polycyclic terpenoid systems with dimethyl acetylenedicarbox…

2001

Polycyclic terpenoid compounds with a methylcyclohexene moiety at the A-ring, such as 1 and 7, give a regio- and stereoselective ene reaction when heated at low temperatures with dimethyl acetylenedicarboxylate. The structure and stereochemistry of the compound formed in the case of 1, e.g. 5, is determined by X-ray analysis.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundchemistryMoietyStereoselectivityGeneral ChemistryRing (chemistry)Medicinal chemistryEne reactionTerpenoid
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Guaranteed and computable error bounds for approximations constructed by an iterative decoupling of the Biot problem

2021

The paper is concerned with guaranteed a posteriori error estimates for a class of evolutionary problems related to poroelastic media governed by the quasi-static linear Biot equations. The system is decoupled by employing the fixed-stress split scheme, which leads to an iteratively solved semi-discrete system. The error bounds are derived by combining a posteriori estimates for contractive mappings with functional type error control for elliptic partial differential equations. The estimates are applicable to any approximation in the admissible functional space and are independent of the discretization method. They are fully computable, do not contain mesh-dependent constants, and provide r…

DiscretizationPoromechanics010103 numerical & computational mathematicsContraction mappings01 natural sciencesFOS: MathematicsDecoupling (probability)Applied mathematicsMathematics - Numerical Analysis0101 mathematicsvirheanalyysiMathematicsa posteriori error estimatesosittaisdifferentiaaliyhtälötA posteriori error estimatesfixed-stress split iterative schemeBiot numberNumerical Analysis (math.NA)Biot problem010101 applied mathematicsComputational MathematicsBiot problem; Fixed-stress split iterative scheme; A posteriori error estimates; Contraction mappingsComputational Theory and MathematicsElliptic partial differential equationModeling and SimulationNorm (mathematics)contraction mappingsA priori and a posterioriFixed-stress split iterative schemenumeerinen analyysiapproksimointiError detection and correction
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Questions de durabilité économique

2016

L’absence d’une approche économique de type systémique, commune et participative, a produit une fragmentation des compétences dans de vastes zones du Sud de l’Italie, ainsi qu’un manque de flexibilité et de durabilité du développement spontané, incontrôlé et sans identité. De plus, cette condition – accompagnée par l’égoïsme et le personnalisme des entreprise et, trop souvent aussi des institutions – a entravé le développement des zones à forte vocation touristique. L’orientation stratégique du développement requiert de la part des habitants et, généralement, de toutes les parties prenantes du territoire (entreprises, commerçants, entreprises sociales, administrations publiques), une capaci…

Drabilité économique Drabilité Créativité Patrimoine Patrimoine culturel Développement économique du territoire L'économie verte Blue Economy Sicilie Agrigento Vallée des TemplesSettore ICAR/21 - Urbanistica
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Infrastructures agroécologiques en droit

2017

International audience; Les infrastructures agroécologiques (IAE) sont une notion récente désignant des éléments naturels, culturels et paysagers, tels les mares, les landes, les haies, les talus, les fossés, les arbres, les bosquets, les bandes enherbées le long des cours d’eau, les murets de pierre ou encore les terrasses. Pendant des siècles, ces milieux physiques sont passés inaperçus pour le droit. Attachés au foncier, ils n’en constituaient qu’un accessoire sommé de suivre le régime juridique du principal. Ces infrastructures étaient sous l’entière maîtrise du propriétaire immobilier pouvant, à sa guise, les créer ou les faire disparaître. Leur statut a cependant c…

Droit rural[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology[SHS.DROIT] Humanities and Social Sciences/Law[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionagroécologie[ SHS.ENVIR ] Humanities and Social Sciences/Environmental studies[SDE.ES]Environmental Sciences/Environmental and Society[ SHS.DROIT ] Humanities and Social Sciences/Law[SDE.BE] Environmental Sciences/Biodiversity and Ecology[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SHS.DROIT]Humanities and Social Sciences/Law[SHS.ENVIR] Humanities and Social Sciences/Environmental studies[SHS.ENVIR]Humanities and Social Sciences/Environmental studiesexploitation agricole[SDE.ES] Environmental Sciences/Environmental and Societyruralpaysage[SDE.BE]Environmental Sciences/Biodiversity and Ecologyinfrastructurespatrimoine naturel[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[ SDE.ES ] Environmental Sciences/Environmental and Societyintérêt écologique
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Drugs and the Colon

1983

It is not our intention to review drug effects in the colon, which was done extensively and profoundly by Forth and Rummel1 and Powell.2 Our contribution will present studies of drug effects on physiological absorption and secretion processes obtained in the intact human colon and based on results of intestinal perfusion studies of the whole colon and measurements of transepithelial electrical potential difference (PD) in the rectosigmoid colon. These are at present the practiced and—regarding perfusion studies—most accurate techniques in the hands of clinicians to directly study drug effects on a local dose-response scale in the intact human colon. Since these methods are relatively new an…

DrugStudy drugbusiness.industryPhysiological Absorptionmedia_common.quotation_subjectRectosigmoid ColonBioinformaticsClinical researchExtensive dataMedicinebusinessPerfusionHuman colonmedia_common
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Optimal Usage of Multiple Network Connections

2008

In the future mobile networks, a mobile terminal is able to select the best suitable network for each data transmission. The selection of a network connection to be used has been under a lot of study. In this paper, we consider a more extensive case in which we do not select a network connection but use several network connections simultaneously to transfer data. When data is transferred using multiple network connections, a network connection has to be selected for each component of the data. We have modelled this problem as a multiobjective optimization problem and developed a heuristic to solve the problem fast in a static network environment. In this paper, we discuss solving the proble…

Dynamic network analysisHeuristic (computer science)Computer scienceDistributed computingInteger programminglangaton tiedonsiirtoTerminal (electronics)optimointiTransfer (computing)Component (UML)langaton viestintäNetwork conditionsSelection (genetic algorithm)Data transmission
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IL RUOLO DEL PATRIMONIO NEL PROGETTO URBANO MARSIGLIA E TUNISI, CITTÁ DEL MEDITERRANEO

La ricerca si occupa del rapporto tra le nuove modalità di trasformazione della città mediterranea e le nuove strategie di rigenerazione e valorizzazione del patrimonio materiale e immateriale. Comprendere qual è il ruolo del patrimonio nel processo di trasformazione e crescita della città mediterranea, attraverso la pratica del progetto urbano, è la questione principale della tesi, che si inserisce nel campo delle ricerche sulle modalità di trasformazione della città contemporanea. La ricerca si interroga, inoltre, su quale sia il rapporto che oggi lega il patrimonio e la sviluppo sostenibile, ambiti non più antitetici ma complementari, in una costruzione reciproca di simbologie e differen…

DÉVELOPPEMENT URBAIN DURABLERECYCLAGEMEDITERRANEOPATRIMOINE IMMATÉRIELMARSEILLESettore ICAR/14 - Composizione Architettonica E UrbanaURBANISMEOBSOLESCENCEPATRIMONIO IMMATERIALEPATRIMONIO URBANOOBSOLESCENZAMÉDITERRANÉEPROGETTO URBANOSVILUPPO URBANO SOSTENIBILEMARSIGLIARICICLOTUNISITUNISPATRIMOINE URBAIN
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