Search results for "Moi"
showing 10 items of 2109 documents
De Finnis cornutis
2014
<p><em>Horned Finns</em>. The ‘cornuti Finni’ mentioned in the <em>Historia Norwegiae</em> have not found their explanation, because the Latin word <em>cornu</em>, from which the adjective is derived, has been understood in the strict sense of ‘horn on the head’. The Latin word, however, also means ‘hoof’ of horses or ‘cloven hoof’ of cows and goats, even of the mythologic Faunus and Pan. In December 1913 Kai Donner saw in Dudinka Avam-Samojeds, who because of their cylindrically shaped reindeer winter boots, the front of which was hoof-shaped, were called ‘hoofed men’ (in Finnish ‘kaviolliset miehet’). In the extracts of Aristeas of Proconnesus, wh…
Metal-atom impact on the self-assembly of cup-and-ball metalloporphyrin–fullerene conjugates
2014
International audience; A fullerene ammonium derivative has been combined with different metalloporphyrin–crown ether receptors to generate very stable supramolecules. The combination of fullerene–porphyrin and ammonium–crown ether interactions leads to a strong chelate effect as evidenced by a high effective molarity (3.16 M). The different parameters influencing the stability of the supramolecular ensembles, in particular the nature of the metal in the porphyrin moiety, have been rationalized with the help of theoretical calculations thus providing new insights into fullerene–porphyrin interactions.
Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
2008
Chalcones are characterized by possessing an enone moiety between two aromatic rings. A series of chalcone-like agents, in which the double bond of the enone system is embedded within a thiophene ring, were synthesized and evaluated for antiproliferative activity and inhibition of tubulin assembly and colchicine binding to tubulin. The replacement of the double bond with a thiophene maintains antiproliferative activity and therefore must not significantly alter the relative conformation of the two aryl rings. The synthesized compounds were found to inhibit the growth of several cancer cell lines at nanomolar to low micromolar concentrations. In general, all compounds having significant anti…
Synthetic O-glycopeptides as model substrates for glycosyltransferases
1993
Abstract A new approach to O-glycopeptides of the glucosamine type is described. N-Urethane protected, peracetylated glucosamine is converted into its 1-thio (1-bromo) derivative and used for glycosylation of a variety of protected serine or threonine derivatives as acceptors. The urethane group is easily exchanged for the natural N-acetyl moiety and O-deacetylation is achieved with hydrazine/methanol. The resulting O-GlcNAc derivatives are subjected to an enzymatic galactosylation procedure using β-1,4-galactosyltransferase (EC 2.4.1.22) to furnish O-glycopeptides of the neolactosamine type.
Glycosylated macromolecular conjugates of antiviral drugs with a polyaspartamide.
2004
Two new polymeric conjugates for specific liver targeting were prepared by conjugation of sugar moieties and antiviral drugs to alpha, beta-poly[N-2-(hydroxyethyl)-DL-aspartamide] (PHEA). PHEA-galactopyranosylphenylthiocarbamide-mono-O-succinylganciclovir (conjugate 7) and PHEA-mannopyranosylphenylthiocarbamide-O-succinylacyclovir (conjugate 8) were synthesized according to a multi-step procedure which allowed for obtaining high product yield and process standardization. Conjugate 7 contained 7.5 and 8.5% of galactose and ganciclovir (substituent/repeating unit, mol/mol), respectively, and conjugate 8 contained 14.2 and 10.8% of mannose and acyclovir, respectively. In vitro studies demonstr…
Le « repas gastronomique des français » inscrit au patrimoine mondial de l’UNESCO : les enjeux du label
2016
National audience
Water and temperature contribution to the structuration of starch matrices in the presence of flavour.
2016
The effect of hydrothermal treatments and flavours addition on starch structure and its physical properties were studied. Native wheat starch was treated at 2 different hydrations (water-starch ratios: 50/50 and 80/20 g w/w) and temperatures (65 and 85 °C) in the presence of flavours (ethyl hexanoate and 2-hexanone). The freshly prepared samples were subjected to DSC and flavour analysis. Flavour inclusion complex could not be detected by DSC, however the result of flavour analysis proved that there were flavours interactions with starch. Both ethyl hexanoate and 2-hexanone interacted with starch at similar rates. The highest flavour loss was found in the samples at high hydration and heate…
PRACTICAL ASPECTS OF THE ANALYSIS OF THE PROGRESSION CURVES OF FIRST AND PSEUDO-FIRST ORDER REACTIONS
2020
The paper presents a simple method of determining iteratively the progression curve asymptote for first and pseudo-first order reactions. For selected student exercises, thus obtained results were compared (see Supplementary Material) with those found by means of the method of determining asymptotes experimentally. A nonlinear fitting method was additionally employed to assess the accuracy.
Parameter identification for heterogeneous materials by optimal control approach with flux cost functionals
2021
The paper deals with the identification of material parameters characterizing components in heterogeneous geocomposites provided that the interfaces separating different materials are known. We use the optimal control approach with flux type cost functionals. Since solutions to the respective state problems are not regular, in general, the original cost functionals are expressed in terms of integrals over the computational domain using the Green formula. We prove the existence of solutions to the optimal control problem and establish convergence results for appropriately defined discretizations. The rest of the paper is devoted to computational aspects, in particular how to handle high sens…
Assessing the Performance of Interactive Multiobjective Optimization Methods
2021
Interactive methods are useful decision-making tools for multiobjective optimization problems, because they allow a decision-maker to provide her/his preference information iteratively in a comfortable way at the same time as (s)he learns about all different aspects of the problem. A wide variety of interactive methods is nowadays available, and they differ from each other in both technical aspects and type of preference information employed. Therefore, assessing the performance of interactive methods can help users to choose the most appropriate one for a given problem. This is a challenging task, which has been tackled from different perspectives in the published literature. We present a …