Search results for "Molecule"

showing 10 items of 5162 documents

Single-molecule magnet properties of a monometallic dysprosium pentalene complex

2018

The pentalene-ligated dysprosium complex [(η8-Pn†)Dy(Cp*)] (1Dy) (Pn† = [1,4-(iPr3Si)2C8H4]2−) and its magnetically dilute analogue are single-molecule magnets, with energy barriers of 245 cm−1. Whilst the [Cp*]− ligand in 1Dy provides a strong axial crystal field, the overall axiality of this system is attenuated by the unusual folded structure of the [Pn†]2− ligand. peerReviewed

magneettiset ominaisuudetMaterials sciencePentalenechemistry.chemical_element010402 general chemistry01 natural sciencesCatalysisCrystalchemistry.chemical_compoundMaterials Chemistrycoordination complexesSingle-molecule magnetta116010405 organic chemistryLigandFolded structureMetals and AlloyskompleksiyhdisteetGeneral Chemistry0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCrystallographychemistryMagnetCeramics and CompositesDysprosiummagnetic propertiesChemical Communications
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Rare‐earth cyclobutadienyl sandwich complexes: Synthesis, structure and dynamic magnetic properties

2018

The potassium cyclobutadienyl [K2{η4‐C4(SiMe3)4}] (1) reacts with MCl3(THF)3.5 (M=Y, Dy) to give the first rare‐earth cyclobutadienyl complexes, that is, the complex anions [M{η4‐C4(SiMe3)4}{η4‐C4(SiMe3)3‐κ‐(CH2SiMe2}]2−, (2M), as their dipotassium salts. The tuck‐in alkyl ligand in 2M is thought to form through deprotonation of the “squarocene” complexes [M{η4‐C4(SiMe3)4}2]− by 1. Complex 2Dy is a single‐molecule magnet, but with prominent quantum tunneling. An anisotropy barrier of 323(22) cm−1 was determined for 2Dy in an applied field of 1 kOe, and magnetic hysteresis loops were observed up to 7 K. nonPeerReviewed

magneettiset ominaisuudetcyclobutadienyl ligandsmagneetitchemistry.chemical_element010402 general chemistry01 natural sciencesCatalysisDeprotonationAnisotropyta116magnetsAlkylQuantum tunnellingchemistry.chemical_classificationkemiallinen synteesiorganometallics dysprosium010405 organic chemistryLigandOrganic ChemistrykompleksiyhdisteetGeneral Chemistryharvinaiset maametallitMagnetic hysteresis0104 chemical sciencesCrystallographychemistryMagnetDysprosiumsingle-moleculerare-earth elements
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Asymmetric Ring Opening in Tetrazine‐based Ligand Affording a Tetranuclear Opto‐Magnetic Ytterbium Complex

2021

We report the formation of a tetranuclear lanthanide cluster, [Yb 4 (bpzch) 2 (fod) 10 ] ( 1 ), which occurs from a serendipitous ring opening of the functionalized tetrazine bridging ligand, bpztz (3,6‐dipyrazin‐2‐yl‐1,2,4,5‐tetrazine) upon reacting with Yb(fod) 3 (fod ‐ = 6,6,7,7,8,8,8‐heptafluoro‐2,2‐dimethyl‐3,5‐octandionate). Compound 1 was structurally elucidated via single‐crystal X‐ray crystallography and subsequently magnetically and spectroscopically characterized to analyse its magnetisation dynamics and its luminescence behaviour. Computational studies validate the observed M J energy levels attained by spectroscopy and provides a clearer picture of the slow relaxation of the ma…

magneettiset ominaisuudetluminesenssitetrazineopto-magnetic propertiesphotoluminescenceytterbiumkompleksiyhdisteetsingle-molecule magnetsharvinaiset maametallitoptiset ominaisuudet
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Triplet-State Position and Crystal-Field Tuning in Opto‐Magnetic Lanthanide Complexes : Two Sides of the Same Coin

2019

Lanthanide complex‐based luminescence thermometry and single‐molecule magnetism are two effervescent research fields, owing to the great promise they hold from an application standpoint. The high thermal sensitivity achievable, their contactless nature, along with sub‐micrometric spatial resolution make these luminescent thermometers appealing for accurate temperature probing in miniaturized electronics. To that end, single‐molecule magnets (SMMs) are expected to revolutionize the field of spintronics, thanks to the improvements made in terms of their working temperature – now surpassing that of liquid nitrogen – and manipulation of their spin state. Hence, the combination of such opto‐magn…

magneettiset ominaisuudetthermometryluminesenssiluminescencelanthanideskompleksiyhdisteetsingle-molecule magnetsharvinaiset maametallitlämpömittaritmolecular structures
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Three-dimensional bimetallic octacyanidometalates $[M^{IV}{(\mu-CN)_{4}Mn^{II}(H_{2}O)_2}_2 \cdot 4H_{2}O]_{n}$ (M=Nb,Mo,W) : synthesis, single-cryst…

2008

Abstract We report the synthesis, the single-crystal X-ray crystallographic structures and the magnetic properties of three new isostructural cyanido-bridged networks: [M IV {(μ-CN) 4 Mn II (H 2 O) 2 } 2 ·4H 2 O] n [M IV  = Nb IV ( 1 ), Mo IV ( 2 ), W IV ( 3 )]. For compound 1 , the magnetic properties reveal a ferrimagnetic phase below 50 K. In contrast, compounds 2 and 3 show a paramagnetic behaviour with no magnetic ordering down to 2 K. The only electronic difference between the two kinds of compounds is the presence of two paired electrons on Mo IV ( 2 ) and W IV ( 3 ) (d 2 electronic configuration, S  = 0) with no possible exchange interactions with Mn II ions (d 5 electronic configur…

magnetic exchange interactionMagnetismGeneral Chemical Engineering010402 general chemistry01 natural sciencesMagnetizationParamagnetismcrystal structuresunpaired electronsstructure cristallineAntiferromagnetismIsostructural010405 organic chemistryChemistrymolecule-based magnetsGeneral Chemistrypont cyanure3. Good health0104 chemical sciencesCrystallographycyanido bridgeUnpaired electronoctacyanométallatesoctacyanidometalatesCurie temperatureinteraction d'échange magnétiqueelectronscélibatairesaimants à précurseurs moléculairesMolecule-based magnets
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Squaric Acid-Based Radiopharmaceuticals for Tumor Imaging and Therapy.

2021

Targeting vectors bound to a chelator represent a significant fraction of radiopharmaceuticals used nowadays for diagnostic and therapeutic purposes in nuclear medicine. The use of squaramides as coupling units for chelator and targeting vector helps to circumvent the disadvantages of several common coupling methods. This review gives an overview of the use of squaric acid diesters (SADE) as linking agents. It focuses on the conjugation of cyclic chelators, e.g., DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), as well as hybrid chelators like AAZTA5 (6-pentanoic acid-6-amino-1,4-diazepine tetracetic acid) or DATA5m (6-pentanoic acid-6-amino-1,4-diazapine-triacetate) to diff…

medicine.drug_classBiomedical EngineeringPharmaceutical ScienceBioengineering02 engineering and technologySquaric acidMonoclonal antibody01 natural scienceschemistry.chemical_compoundFibroblast activation protein alphaIn vivoNeoplasmsmedicineDOTAHumansChelationPharmacology010405 organic chemistryChemistryOrganic Chemistry021001 nanoscience & nanotechnologyCombinatorial chemistrySmall molecule0104 chemical sciencesPositron-Emission TomographyRadiopharmaceuticals0210 nano-technologyCyclobutanesBiotechnologyConjugateBioconjugate chemistry
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Theoretical prediction of the photoinduced chemiluminescence of pesticides

2007

Although it is relatively easy to find chemiluminescent (CL) molecules working on the field of direct liquid phase (especially employing strong oxidants), the molecules found as chemiluminescent are normally very weak CL compounds for developing suitable analytical CL-procedures. Therefore, it is mandatory to develop new strategies to enhance in a simple way the native chemiluminescence of such a compounds, and even to increase the number of compounds to be determined by direct chemiluminescence. Photoinduced chemiluminescence (Ph-CL) results in a simple and easily on-line accessible strategy to solve these disadvantages. In the present paper, molecular connectivity, a topological method wh…

medicine.drug_classCarboxamideSulfuric acidOximeAnalytical Chemistrylaw.inventionchemistry.chemical_compoundPotassium permanganatechemistryComputational chemistrylawmedicineOrganic chemistryMoleculePhotodegradationThiocarbamatesChemiluminescenceTalanta
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Monoclonal antibodies to polysialic acid reveal epitope sharing between invasive pathogenic bacteria, differentiating cells and tumor cells

1987

Monoclonal antibodies (mAb) for rapid diagnosis and detection of invasive bacteria and identification of pathogenic factors in infectious disease are equally important in medical microbiology and clinical pathology and may even provide a breakthrough in basic medical and cell biology research. Such a situation evolved from the application of a unique mAb against the poorly immunogenic homopolymers of alpha 2,8-linked sialic acid of Escherichia coli K1 and meningococci group B capsules which could be derived from immune-hyperreactive NZB-autoimmune mice. The cross-reactivity of this mAb with identical polysialic acid (polySA) units of the neural cell adhesion molecule (N-CAM) revealed antige…

medicine.drug_classImmunologyKidneyMonoclonal antibodyWilms TumorEpitopeMicrobiologyEpitopeschemistry.chemical_compoundImmune systemAntigenmedicineAnimalsHumansBacteriabiologyPolysialic acidAntibodies MonoclonalCell DifferentiationKidney NeoplasmsSialic acidchemistryAntigens SurfaceSialic Acidsbiology.proteinNeural cell adhesion moleculeAntibodyCell Adhesion MoleculesImmunologic Research
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Non-covalent interactions of N-phenyl-1,5-dimethyl-1H-imidazole-4-carboxamide 3-oxide derivatives—a case of intramolecular N-oxide hydrogen bonds

2017

The crystal structures of new N-phenyl-1,5-dimethyl-1H-imidazole-4-carboxamide 3-oxide derivatives are reported. The results of X-ray diffraction showed the existence of intramolecular hydrogen bonding between carboxamide nitrogen donors and N-oxide oxygen acceptors. The use of Quantum Theory of Atoms in Molecules allowed its classification as a strong interaction, with energy about 10 kcal/mol, and of intermediate character between closed shell and shared bonds. Comparison of experimental data and quantum theoretical calculations indicated that a substituent attached to the phenyl ring in the para position influences the strength and geometry of the title hydrogen bonding. Stronger π-elect…

medicine.drug_classLow-barrier hydrogen bondintramolecular hydrogen bondSubstituentCarboxamideN-oxide group010402 general chemistry01 natural scienceschemistry.chemical_compoundComputational chemistrymedicineNon-covalent interactionsHirshfeld surface analysisPhysical and Theoretical Chemistrychemistry.chemical_classification010405 organic chemistryHydrogen bondIntermolecular forceAtoms in moleculesCondensed Matter Physicshydrogen bonding0104 chemical sciencesCrystallographychemistryQTAIMIntramolecular forcesubstituent effectStructural Chemistry
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Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions

1988

Abstract Most epithelial sheets emerge during embryogenesis by a branching and growth of the epithelium. The surrounding mesenchyme is crucial for this process. We report that branching morphogenesis and the formation of a new epithelium from the mesenchyme in the embryonic kidney can be blocked by a monoclonal antibody reacting with a surface glycolipid, disialoganglioside G D3 . In contrast, a more than 10-fold excess of antibodies to adhesive glycoproteins (N-CAM, L -CAM, fibronectin) fails to inhibit morphogenesis. Although the anti-G D3 antibody affected epithelial development, the disialoganglioside G D3 was expressed not in the epithelium, but in the mesenchyme surrounding the develo…

medicine.drug_classMesenchymeMorphogenesisFluorescent Antibody TechniqueBiologyKidneyMonoclonal antibodyEpitheliumGeneral Biochemistry Genetics and Molecular BiologyMesodermMiceOrgan Culture TechniquesCell–cell interactionGangliosidesMorphogenesismedicineAnimalsGanglioside GD3Embryonic InductionMembrane GlycoproteinsAntibodies MonoclonalEmbryonic stem cellEpitheliumFibronectinsCell biologyFibronectinmedicine.anatomical_structureBiochemistryAntigens Surfacebiology.proteinUreterCell Adhesion MoleculesCell
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