Search results for "Molluscacides"

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New Biologically Active Triterpene-Saponins fromRandia dumetorum

1990

Two new triterpene-saponins, 3-O-[O-beta-D-glucopyranosyl-(1----4)-O-beta-D-glucopyranosyl-(1----3)-( beta- D-glucuronopyranosyl)]oleanolic acid (1), 3-O-[O-beta-D-glucopyranosyl-(1----6)-O-beta-D-glucopyranosyl- (1----3)-(beta-D-glucuronopyranosyl)]oleanolic acid (2) together with five known saponins (3-7) were isolated from the methanolic extract of the fruits of Randia dumetorum (Retz) Lam. (Rubiaceae). Their structures were established on the basis of chemical and spectral data. The compounds 1, 3, 4, 5 were found to enhance significantly the proliferation of human lymphocytes in vitro. The crude saponin fraction showed haemolytic, molluscicidal, and immunostimulating activities.

MolluscacidesStereochemistryRandiaSaponinPharmaceutical SciencePharmacognosyLymphocyte ActivationAnalytical Chemistrychemistry.chemical_compoundTriterpeneDrug DiscoveryAnimalsLymphocytesMedicinal plantsOleanolic acidPharmacologychemistry.chemical_classificationPlants MedicinalRubiaceaeBiomphalariabiologyOrganic ChemistrySaponinsbiology.organism_classificationTriterpenesTerpenoidcarbohydrates (lipids)Complementary and alternative medicinechemistryMolecular MedicinePlanta Medica

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