Search results for "Mono"
showing 10 items of 6843 documents
Optical method for predicting the composition of self-assembled monolayers of mixed thiols on surfaces coated with silver nanoparticles.
2012
With a simple optical method, based on UV-vis absorption spectra on glass slides, it is possible to predict the composition of self-assembled monolayers of mixed thiols, grafted on monolayers of silver nanoparticles. Glass slides are modified with the layer-by-layer technique, first forming a monolayer of mercaptopropyltrimethoxysilane, then grafting a monolayer of silver nanoparticles on it. These surfaces are further coated by single or mixed thiol monolayers, by dipping the slides in toluene solutions of the chosen thiols. Exchange constants are calculated for the competitive deposition between the colorless 1-dodecanethiol or PEG5000 thiol and BDP-SH, with the latter being a thiol-beari…
Structural and Dynamic Properties of the Homodimeric Hemoglobin from Scapharca inaequivalvis Thr-72→Ile Mutant: Molecular Dynamics Simulation, Low Te…
1998
AbstractMolecular dynamics simulations, low temperature visible absorption spectroscopy, and resonance Raman spectroscopy have been performed on a mutant of the Scapharca inaequivalvis homodimeric hemoglobin, where residue threonine 72, at the subunit interface, has been substituted by isoleucine. Molecular dynamics simulation indicates that in the Thr-72→Ile mutant several residues that have been shown to play a role in ligand binding fluctuate around orientations and distances similar to those observed in the x-ray structure of the CO derivative of the native hemoglobin, although the overall structure remains in the T state. Visible absorption spectroscopy data indicate that in the deoxy …
Radiation from multi-GeV electrons and positrons in periodically bent silicon crystal
2014
A periodically bent Si crystal is shown to efficiently serve for producing highly monochromatic radiation in a gamma-ray energy spectral range. A short-period small-amplitude bending yields narrow undulator-type spectral peaks in radiation from multi-GeV electrons and positrons channeling through the crystal. Benchmark theoretical results on the undulator are obtained by simulations of the channeling with a full atomistic approach to the projectile-crystal interactions over the macroscopic propagation distances. The simulations are facilitated by employing the MBN Explorer package for molecular dynamics calculations on the meso-, bio- and nano-scales. The radiation from the ultra-relativist…
Performance of a Chromolith RP-18e column for the screening of β-blockers
2009
The chromatographic performance of a monolithic column (Chromolith RP-18e) was comprehensively examined in the isocratic separation of ten beta-blockers, using ACN-water mobile phases, and compared with the performance of three microparticulate RP columns manufactured with different types of silica: Spherisorb ODS-2, Kromasil C18 and XTerra MS C18. The comparison considered the analysis time, selectivity, peak shape (column efficiency and asymmetry) and resolution, and was extended to a wide range of mobile phase compositions. The Chromolith column showed good performance for the analysis of beta-blockers with regard to the packed columns. In terms of selectivity and analysis time, the grea…
CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia
2005
Contains fulltext : 47591.pdf (Publisher’s version ) (Closed access) Achromatopsia is a congenital, autosomal recessively inherited disorder characterized by a lack of color discrimination, low visual acuity (<0.2), photophobia, and nystagmus. Mutations in the genes for CNGA3, CNGB3, and GNAT2 have been associated with this disorder. Here, we analyzed the spectrum and prevalence of CNGB3 gene mutations in a cohort of 341 independent patients with achromatopsia. In 163 patients, CNGB3 mutations could be identified. A total of 105 achromats carried apparent homozygous mutations, 44 were compound (double) heterozygotes, and 14 patients had only a single mutant allele. The derived CNGB3 mutatio…
Mutations in the Cone Photoreceptor G-Protein α-Subunit Gene GNAT2 in Patients with Achromatopsia
2002
Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination. We here report the identification of five independent families with achromatopsia that segregate protein-truncation mutations in the GNAT2 gene, located on chromosome 1p13. GNAT2 encodes the cone photoreceptor-specific alpha-subunit of transducin, a G-protein of the phototransduction cascade, which couples to the visual pigment(s). Our results demonstrate that GNAT2 is the third gene implicated in achromatopsia.
Anionic Polymerization of (Meth)acrylates in the Presence of Cesium Halide−Trialkylaluminum Complexes in Toluene
2001
The polymerization of methyl methacrylate and various acrylates initiated by ester enolates in the presence of cesium halide-trialkylaluminum complexes, Cs[Al n R 2n X] (n = 1, 2; R = Et, Bu'), in toluene has living and controlled character at -20 °C for methacrylates (X = Cl) and at -65 °C for n-butyl acrylate (X = F). Quantitative monomer conversions are usually reached, leading to polymers with narrow molecular weight distributions (M w /M n < 1.1). Kinetic investigations indicate a rather complex polymerization mechanism, and we assume an equilibrium between at least two active species. With this new initiating system, beside acrylate homopolymers, random and graft copolymers can be syn…
Characterization of sulfobetaine monomers by nuclear magnetic resonance spectroscopy: a note
1995
A set of zwitterionic monomers bearing the 3-ammoniopropanesulfonate moiety is analysed in CDCl3, CD3OD and D2O by one- and two-dimensional H-1 n.m.r. and C-13 n.m.r. spectroscopy. Absolute and relative positions of the n.m.r, signals are determined depending on the solvent used; the refined assignments of the signals in the vicinity of the ammonium group deviate from previously proposed assignments based on standard n.m.r, shift tables. Still, there is no convincing evidence for a special ring current effect due to a six-membered ring conformation of the betaine moiety.
Polymerizable and polymeric zwitterionic surfactants: 2. Surface activity and aggregation behaviour in aqueous systems
1991
Abstract The surfactant properties of a series of permanently zwitterionic monomers and polymers were studied with respect to structural variations. A strong influence of the molecular geometry on solubility and aggregation behaviour was observed, in particular for the polymers. Whereas all monomers were water-soluble and true surfactants, the water solubility of the polymers was restricted to selected geometries. Water-soluble polymers showed the properties of classical polysoaps, i.e. low surface activity and solubilization power for hydrophobic solutes. In contrast, water-insoluble polymers formed stable monolayers at the air-water interface and could be deposited onto solid substrates b…
Molecular Recognition by Hydrogen Bonding in Polyelectrolyte Multilayers
1997
Functional polyanions were prepared by copolymerization of sulfopropyl acrylate and sulfopropyl methacrylate with monomers bearing triaminopyrimidine or barbituric acid functionalities, respectively. Functionalized polyelectrolyte multilayers were assembled from these copolymers by stepwise alternating adsorption with poly(choline methacrylate). These multilayers are suited for molecular recognition of substrates that are complementary to the functional groups incorporated. Thus, multilayers containing triaminopyrimidine moieties selectively bind barbituric acid, and vice versa, when exposed to solutions of the 1:1 complex of barbituric acid and triaminopyrimidine. The molecular recognition…