Search results for "Mono"
showing 10 items of 6843 documents
Hartinga strupastes, Microtus hartingi (Arvicolinae, Sumeriomys apakšģints) komunālās vairošanās ietekme uz mātīšu reproduktīvajām sekmēm
2019
Lai pārbaudītu hipotēzi, ka dažādas sociālās sistēmas un uzvedība ir saistīta ar vidi, ko suga apdzīvo, izmanto salīdzinošo metodi, kas pēta taksonomiski tuvu radnieciskas sugas, kurām atšķiras dzīves vide. Darba mērķis ir apskatīt atšķirības divu Microtus hartingi pasugu vairošanās stratēģijās saistībā ar pasugas veidošanos fragmentētā areālā. Darbā, lai novērtētu tēviņu rūpju intensitāti par saviem mazuļiem un mātīšu reproduktīvās sekmes monogāmās grupās un poligīnās grupās ar svešām vai radnieciskām mātītēm, tika izmantotas divas Microtus hartingi pasugas – Microtus hartingi hartingi un Microtus hartingi lydius. Eksperimenti tika veikti laboratorijas apstākļos. Lai novērtētu vairošanās s…
Tradicionālais apģērbs Japānā: Vēsture un mūsdienu interpretācija
2021
Darba tēma ir „Tradicionālais apģērbs Japānā: Vēsture un mūsdienu interpretācija”. Tēma ir izvēlēta tāpēc, ka apģērbs ir jebkuras kultūras ļoti būtiska sastāvdaļa, kas atspoguļo gan konkrētas tautas vēsturisko attīstību vispārīgi, gan liecina par vērtībām, ieražām un ikdienas dzīvesveidu, kultūru un filozofiju. Ir būtiski mūsdienās šīs vēstures liecības apzināt un saglabāt, kā arī analizēt no dažādiem skatpunktiem. Kimono aktualitāte pēdējā gadsimta gaitā ir mazinājusies un to vairs nenēsā kā ikdienas apģērbu, bet mūsdienās tas vēl joprojām īpaši populārs ir svētku un svarīgu notikumu laikā. Autores darba novitāte ir saistīta ar praktisko izpēti par šīs tautastērpa ietekmi mūsdienu Japāņu a…
Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3
2005
hCAT-3 (human cationic amino acid transporter type three) was investigated with both the two-electrode voltage clamp method and tracer experiments. Oocytes expressing hCAT-3 displayed less negative membrane potentials and larger voltage-dependent currents than native or water-injected oocytes did. Ion substitution experiments in hCAT-3-expressing oocytes revealed a large conductance for Na + and K + . In the presence of l-Arg, voltage-dependent inward and outward currents were observed. At symmetrical (inside/outside) concentrations of l-Arg, the conductance of the transporter increased monoexponentially with the l-Arg concentrations; the calculated Vmax and KM values amounted to 8.3 AS and…
Optimized Deposition of Graphene Oxide Langmuir-Blodgett Thin Films
2014
Abstract Single sheet graphene (SG) is an innovative transparent material with high electrical and thermal conduction the use of which in transparent electrodes instead of traditional materials improves the performance of optoelectronic devices. In this study, graphene oxide (GO) has been obtained by a modified Hummer`s method followed by an advanced technique of water removal (lyophilisation). The Langmuir-Blodgett (LB) method was applied to transfer GO from suspension to substrate. To optimize the deposition process, as suspending and spreading solvents the benzene and benzene/methanol mixtures were chosen instead of previously studied water suspensions. The number of GO layers in suspens…
SNAPSHOT SPECTRAL AND COLOR IMAGING USING A REGULAR DIGITAL CAMERA WITH A MONOCHROMATIC IMAGE SENSOR
2017
Spectral imaging (SI) refers to the acquisition of the three-dimensional (3D) spectral cube of spatial and spectral data of a source object at a limited number of wavelengths in a given wavelength range. Snapshot spectral imaging (SSI) refers to the instantaneous acquisition (in a single shot) of the spectral cube, a process suitable for fast changing objects. Known SSI devices exhibit large total track length (TTL), weight and production costs and relatively low optical throughput. We present a simple SSI camera based on a regular digital camera with (i) an added diffusing and dispersing phase-only static optical element at the entrance pupil (diffuser) and (ii) tailored compressed sensing…
Climate and extreme rainfall events in the Mono river basin (West Africa): investigating future changes with Regional Climate Models.
2020
This study characterizes the future changes in extreme rainfall and air temperature in the Mono river basin where the main economic activity is weather dependent and local populations are highly vulnerable to natural hazards, including flood inundations. Daily precipitation and temperature from observational datasets and Regional Climate Models (RCMs) output from REMO, RegCM, HadRM3, and RCA were used to analyze climatic variations in space and time, and fit a GEV model to investigate the extreme rainfalls and their return periods. The results indicate that the realism of the simulated climate in this domain is mainly controlled by the choice of the RCMs. These RCMs projected a 1 to 1.5 °
Mycobacterium tuberculosis Drives Expansion of Low-Density Neutrophils Equipped With Regulatory Activities
2019
In human tuberculosis (TB) neutrophils represent the most commonly infected phagocyte but their role in protection and pathology is highly contradictory. Moreover, a subset of low-density neutrophils (LDNs) has been identified in TB, but their functions remain unclear. Here, we have analyzed total neutrophils and their low-density and normal-density (NDNs) subsets in patients with active TB disease, in terms of frequency, phenotype, functional features, and gene expression signature. Full-blood counts from Healthy Donors (H.D.), Latent TB infected, active TB, and cured TB patients were performed. Frequency, phenotype, burst activity, and suppressor T cell activity of the two different subse…
Targeting B Cell Maturation Antigen (BCMA) in Multiple Myeloma: Potential Uses of BCMA-Based Immunotherapy
2018
The approval of the first two monoclonal antibodies targeting CD38 (daratumumab) and SLAMF7 (elotuzumab) in late 2015 for treating relapsed and refractory multiple myeloma (RRMM) was a critical advance for immunotherapies for multiple myeloma (MM). Importantly, the outcome of patients continues to improve with the incorporation of this new class of agents with current MM therapies. However, both antigens are also expressed on other normal tissues including hematopoietic lineages and immune effector cells, which may limit their long-term clinical use. B cell maturation antigen (BCMA), a transmembrane glycoprotein in the tumor necrosis factor receptor superfamily 17 (TNFRSF17), is expressed a…
Role of Peripheral Immune Cells-Mediated Inflammation on the Process of Neurodegenerative Diseases
2020
Neurodegenerative diseases are characterized by progressive loss of selectively vulnerable neuronal populations, which contrasts with selectively static loss of neurons due to toxic or metabolic disorders. The mechanisms underlying their progressive nature remain unknown. To date, a timely and well-controlled peripheral inflammatory reaction is verified to be essential for neurodegenerative diseases remission. The influence of peripheral inflammation on the central nervous system is closely related to immune cells activation in peripheral blood. The immune cells activation participated in the uncontrolled and prolonged inflammation that drives the chronic progression of neurodegenerative di…
Immunological Markers for PML Prediction in MS Patients Treated with Natalizumab
2015
International audience; Natalizumab (NTZ), a monoclonal antibody recognizing the alpha4 integrin chain, has been approved for the treatment of active multiple sclerosis, but expose to the onset of a rare side effect, progressive multifocal leukoencephalopathy (PML). Estimating the individual risk of PML in NTZ-treated patients is a major challenge, and therapeutic strategies are mainly guided by the overall PML risk assessed by identified risk factors: JC virus (JCV) seropositivity, treatment duration (with peak incidence after 24 months), and the previous use of immunosuppressive therapies. Given that this stratification does not yet allow a precise individual prediction of PML, other pred…