Search results for "Mosaic"

showing 10 items of 208 documents

Mandible morphology, dental microwear, and diet of the extinct giant rats Canariomys (Rodentia: Murinae) of the Canary Islands (Spain)

2010

An ecomorphological approach of mandible shape through Fourier analyses combined with a paleodietary analysis of dental microwear patterns is used to reconstruct the diet of the extinct endemic Canariomys bravoi Crusafont, Pairo & Petter, 1964 and Canariomys tamarani Lopez-Martinez & Lopez-Jurado, 1987. These two large rodents, respectively, lived on Tenerife and Gran Canaria, the central islands of the Canarian Archipelago. Mandible shape and dental microwear respectively inform us on the volume of vegetal matter and on the presence of grass in the diet. Both Canariomys, which are of similar size, possess relatively similar mandible outlines and microwear patterns. For each species, a diet…

0106 biological sciencesMorphometrics010506 paleontologygeographygeography.geographical_feature_categorybiologyEcologyMosaic evolutionZoologyMurinaeCanariomys15. Life on landbiology.organism_classification010603 evolutionary biology01 natural sciencesMandible (arthropod mouthpart)Canariomys tamaraniArchipelago14. Life underwaterAllometryEcology Evolution Behavior and Systematics0105 earth and related environmental sciencesBiological Journal of the Linnean Society
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Viral fitness determines the magnitude of transcriptomic and epigenomic reprograming of defense responses in plants

2020

Although epigenetic factors may influence the expression of defense genes in plants, their role in antiviral responses and the impact of viral adaptation and evolution in shaping these interactions are still poorly explored. We used two isolates of turnip mosaic potyvirus with varying degrees of adaptation to Arabidopsis thaliana to address these issues. One of the isolates was experimentally evolved in the plant and presented increased load and virulence relative to the ancestral isolate. The magnitude of the transcriptomic responses was larger for the evolved isolate and indicated a role of innate immunity systems triggered by molecular patterns and effectors in the infection process. Sev…

0106 biological sciencesPotyvirusAdaptation BiologicalArabidopsisTurnip mosaic virus01 natural sciencesEpigenesis Genetic03 medical and health sciencesEpigenomeBiotic stressGeneticsPlant–virus interactionTurnip mosaic virusEpigeneticsMolecular BiologyGeneRNA-Directed DNA MethylationEcology Evolution Behavior and Systematics030304 developmental biologyEpigenomicsGenetics0303 health sciencesbiologyRNA-directed DNA methylationsystems biologyEpigenomevirus adaptationDNA Methylationbiology.organism_classificationBiological EvolutionRNA silencingExperimental evolutionHost-Pathogen InteractionsDNA methylationMethylomeGenetic FitnessTranscriptome010606 plant biology & botany
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The gypsy database (GyDB) of mobile genetic elements: release 2.0

2011

This article introduces the second release of the Gypsy Database of Mobile Genetic Elements (GyDB 2.0): a research project devoted to the evolutionary dynamics of viruses and transposable elements based on their phylogenetic classification (per lineage and protein domain). The Gypsy Database (GyDB) is a long-term project that is continuously progressing, and that owing to the high molecular diversity of mobile elements requires to be completed in several stages. GyDB 2.0 has been powered with a wiki to allow other researchers participate in the project. The current database stage and scope are long terminal repeats (LTR) retroelements and relatives. GyDB 2.0 is an update based on the analys…

0106 biological sciencesProtein domainretroelementsLineage (evolution)[SDV]Life Sciences [q-bio]Retroviridae ProteinsCaulimoviridaeEukaryote evolutioncomputer.software_genrephylogeny01 natural sciencesDatabases GeneticRefSeqPhylogenyPriority journalbase de données0303 health sciencesRetrovirusPhylogenetic treeDatabaseSequence analysisdatabases geneticArticlesClassificationChemistryGenetic lineRetroelementsGenetic databaseComputer programBiologyArticleMobile genetic element03 medical and health sciencesLong terminal repeatWeb pagephylogénieVirus proteinGeneticsLife Science[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyAccess to informationTransposon030304 developmental biologyretroelements;phylogeny;software;terminal repeat sequences;databases geneticHidden Markov modelCauliflower mosaic virusCaulimovirussoftwareRetroposonTerminal Repeat SequencesDNA structureInterspersed Repetitive Sequencesterminal repeat sequencesNonhumanRetroviridaeData analysis softwareGenetic variabilityMobile genetic elementscomputerLENGUAJES Y SISTEMAS INFORMATICOSSoftware010606 plant biology & botanyPhylogenetic nomenclaturePhylogenetic tree
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Landscape-scale simulation experiments test Romanian and Swiss management guidelines for mountain pasture-woodland habitat diversity

2016

Distinct guidelines have been proposed in Romania and Switzerland for the management of pasture woodlands that either focused on the regulation of grazing pressure (Romanian production perspective) or overall tree cover (Swiss conservation perspective). However, the landscape structural diversity and the cover of forest-grassland ecotones, which are both crucial for nature conservation value, were not explicitly considered. We aimed to compare the country-specific management guidelines regarding their efficiency for the conservation of the structurally diverse forest-grassland mosaics in the light of recent land-use and climate change. In strategic simulation experiments using the process-b…

0106 biological sciencesSouthern CarpathiansClimate change adapted managementClimate changeWoodland010603 evolutionary biology01 natural sciencesForest-grassland ecotoneGrazing pressureJura MountainsForest-grassland mosaicGrazingComputingMilieux_MISCELLANEOUS2. Zero hungerTree canopy[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyAgroforestryEcological ModelingGlobal warming15. Life on landLow-intensity grazing010601 ecologyGeographyHabitat13. Climate actionConservation status[SDE.BE]Environmental Sciences/Biodiversity and Ecology
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Abstracts of presentations on plant protection issues at the fifth international Mango Symposium Abstracts of presentations on plant protection issue…

1997

0106 biological sciencesZucchini yellow mosaic virusBarley stripe mosaic virusbiologyEcology (disciplines)Plant ScienceCoat proteinbiology.organism_classification01 natural sciencesCucumber mosaic virus010602 entomologyInsect ScienceInternational congressBotany010606 plant biology & botanyPhytoparasitica
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Last tesserae of a fading mosaic: floristic census and forest vegetation survey at Parche di Bilello (south-western Sicily, Italy), a site needing ur…

2021

This paper illustrates the botanic heritage of Parche di Bilello, a site located in the municipality of Castelvetrano. The study area hosts several woodland fragments dominated by Olea europaea var. sylvestris, Quercus suber and Quercus ilex, respectively. According to historical data, these nuclei represent the last remnants of an open forestland which covered a much wider coastal area between Mazara del Vallo and Sciacca until the end of Middle Age. Phytosociological relevés were focused on these forest nuclei, probably the most representative of south-western Sicily, which correspond to three habitats included in the 92/43 EEC Directive (9320, 9330 and 9340, respectively) and represent t…

0106 biological sciencesforest vegetationlandscape historynature conservationMosaic (geodemography)Plant Science010603 evolutionary biology01 natural sciencesendangered plant speciesFloristicsSB1-1110floristic inventoriesFadingQK900-989Plant ecologyEcology Evolution Behavior and SystematicsEcologyPlant cultureForestryForestryEndangered plant species floristic inventories forest vegetation landscape history nature conservationCensusGeographySettore BIO/03 - Botanica Ambientale E ApplicataForest vegetation010606 plant biology & botanyPlant Sociology
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Role of host genetic diversity for susceptibility-to-infection in the evolution of virulence of a plant virus

2019

Predicting viral emergence is difficult due to the stochastic nature of the underlying processes and the many factors that govern pathogen evolution. Environmental factors affecting the host, the pathogen and the interaction between both are key in emergence. In particular, infectious disease dynamics are affected by spatiotemporal heterogeneity in their environments. A broad knowledge of these factors will allow better estimating where and when viral emergence is more likely to occur. Here, we investigate how the population structure for susceptibility-to-infection genes of the plant Arabidopsis thaliana shapes the evolution of Turnip mosaic virus (TuMV). For doing so we have evolved TuMV …

0106 biological sciencesinfection matrixPopulationPotyvirusVirulenceMetapopulation010603 evolutionary biology01 natural sciencesMicrobiology03 medical and health sciencesVirologyPlant virusTurnip mosaic virusResistance to infectionexperimental evolutioneducationPathogenhost population structure030304 developmental biologyvirus evolution0303 health sciencesExperimental evolutioneducation.field_of_studyGenetic diversitybiologyEcotypeGenetic heterogeneityEvolution of virulenceHost population structureresistance to infectionbiology.organism_classificationInfection matrixVirus evolutionExperimental evolutionInfectious disease (medical specialty)Evolutionary biologyViral evolutionResearch Articleevolution of virulence
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Molecular diagnosis of PIK3CA-related overgrowth spectrum (PROS) in 162 patients and recommendations for genetic testing.

2017

Postzygotic activating mutations of PIK3CA cause a wide range of mosaic disorders collectively referred to as PIK3CA-related overgrowth spectrum (PROS). We describe the diagnostic yield and characteristics of PIK3CA sequencing in PROS. We performed ultradeep next-generation sequencing (NGS) of PIK3CA in various tissues from 162 patients referred to our clinical laboratory and assessed diagnostic yield by phenotype and tissue tested. We identified disease-causing mutations in 66.7% (108/162) of patients, with mutant allele levels as low as 1%. The diagnostic rate was higher (74%) in syndromic than in isolated cases (35.5%; P = 9.03 × 10−5). We identified 40 different mutations and found stro…

0301 basic medicineAdultMalePathologymedicine.medical_specialtyAdolescentGenotypeClass I Phosphatidylinositol 3-KinasesPrenatal diagnosisBioinformaticsmedicine.disease_causeDNA sequencing03 medical and health sciencesYoung Adult0302 clinical medicinePrenatal DiagnosisGenotypemedicineHumansGenetic Predisposition to DiseaseGenetic TestingAlleleChildGenetics (clinical)AllelesGenetic Association StudiesGrowth DisordersGenetic testingMutationmedicine.diagnostic_testbusiness.industryMosaicismInfant NewbornDisease ManagementHigh-Throughput Nucleotide SequencingInfantSequence Analysis DNAPhenotype030104 developmental biologyPhenotypeAmino Acid SubstitutionChild PreschoolMutationAllelic heterogeneityFemalebusiness030217 neurology & neurosurgeryGenetics in medicine : official journal of the American College of Medical Genetics
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Incomplete Timothy syndrome secondary to a mosaic mutation of the CACNA1C gene diagnosed using next-generation sequencing.

2016

Autosomal dominant genetic diseases can occur de novo and in the form of somatic mosaicism, which can give rise to a less severe phenotype, and make diagnosis more difficult given the sensitivity limits of the methods used. We report the case of female child with a history of surgery for syndactyly of the hands and feet, who was admitted at 6 years of age to a pediatric intensive care unit following cardiac arrest. The electrocardiogram (ECG) showed a long QT interval that on occasions reached 500 ms. Despite the absence of facial dysmorphism and the presence of normal psychomotor development, a diagnosis of Timothy syndrome was made given the association of syndactyly and the ECG features.…

0301 basic medicineCalcium Channels L-TypeLong QT syndromeDNA Mutational AnalysisTimothy syndrome030204 cardiovascular system & hematologyBioinformaticsDNA sequencing03 medical and health sciencessymbols.namesakeElectrocardiography0302 clinical medicineGeneticsmedicineMissense mutationHumansSyndactylyAutistic DisorderChildCodonGenetics (clinical)AllelesGenetic Association StudiesSanger sequencingbiologyMosaicismKCNE2High-Throughput Nucleotide Sequencingmedicine.diseaseLong QT Syndrome030104 developmental biologyPhenotypeAmino Acid SubstitutionMutation (genetic algorithm)Mutationsymbolsbiology.proteinFemaleSyndactylyAmerican journal of medical genetics. Part A
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High genetic stability of potato yellow mosaic Panama virus infecting tomato in Panama

2018

The relevant regions in Panama involved in commercial tomato production, including the Chiriqui, Veraguas, Herrera, Los Santos and Panama Oeste provinces, were surveyed for the distribution and genetic diversity of potato yellow mosaic Panama virus (PYMPV) in the growing seasons of 2011 and 2012. A total of 28 tomato plots were surveyed and 314 individual tomato plants were sampled. DNA was extracted from each plant for a subsequent rolling circle amplification (RCA) analysis, to confirm the presence of begomovirus infections. The samples displaying a positive RCA reaction were subsequently analysed by PCR with a specific primer pair to identify PYMPV. This virus was detected in samples col…

0301 basic medicineCloningGenetic diversityVeterinary medicinePanamaBegomovirusfood and beveragesBegomovirus . Rolling circle amplification . Single-strand conformation polymorphism . Phylogenetic analysis . Solanum lycopersicumSettore AGR/12 - Patologia VegetaleSingle-strand conformation polymorphismPlant ScienceBiologybiology.organism_classificationVirus03 medical and health sciences030104 developmental biologyRolling circle replicationPotato yellow mosaic Panama virus
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