Search results for "Multicenter"

showing 10 items of 378 documents

German registry for acute aortic dissection type A (GERAADA)--lessons learned from the registry.

2010

A German registry for acute aortic dissection type A (GERAADA) was initiated by the Working Group for Aortic Surgery and Interventional Vascular Surgery of the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) in July 2006. This web-based database was developed to record the data of patients who had undergone surgery for aortic dissection type A. From analyzing the data, we aim to learn how to improve surgical treatment and to identify parameters affecting patient outcome. In the beginning, 33 cardiac centers participated via online access to the registry on the GSTCVS' homepage. Since then, 43 centers in Germany, Switzerland and Austria have begun entering data on the pre- an…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyMEDLINERisk AssessmentGermanBlood Vessel Prosthesis ImplantationAneurysmGermanymedicineHumansRegistriesSurgical treatmentSocieties MedicalAortic dissectionInternetbusiness.industryGeneral surgeryPatient SelectionVascular surgeryMiddle Agedmedicine.diseaseAortic surgerylanguage.human_languageAortic AneurysmAortic DissectionTreatment OutcomeMulticenter studyAustriaAcute DiseaselanguageSurgeryFemaleMedical emergencyCardiology and Cardiovascular MedicinebusinessSwitzerlandThe Thoracic and cardiovascular surgeon
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469: Prospective, randomized, multicenter trial comparing conversion to a CNI-free regimen (MMF & sirolimus) vs. a CNI-reduced, MMF-based immunos…

2007

Pulmonary and Respiratory MedicineTransplantationmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentUrologyRenal functionImmunosuppressionRegimenMulticenter trialSirolimusmedicineSurgeryCardiology and Cardiovascular Medicinebusinessmedicine.drugThe Journal of Heart and Lung Transplantation
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P1.06-046 Can We Better Manage Advanced NSCLC in the Elderly with the New Therapeutic Agents? Preliminary Analysis of a Real-Life Multicenter Study

2017

Pulmonary and Respiratory Medicinemedicine.medical_specialtyOncologyMulticenter studybusiness.industrymedicineIntensive care medicinebusinessPreliminary analysisJournal of Thoracic Oncology
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German Registry for Acute Aortic Dissection Type A (GERAADA)--new software design, parameters and their definitions.

2011

BACKGROUND The working group for aortic surgery and interventional vascular surgery of the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) initiated the web-based German Registry for Acute Aortic Dissection type A (GERAADA). It is the project's aim to collect standardized data from a large pool of patients with acute aortic dissections type A (AADA) to gain a deeper insight and knowledge to improve surgical therapies and perioperative management for these patients in the future. METHODS In addition to new medical insights, the working group has gained more experience over the last 4 years in how to collect valid and high-quality data. This experience led us to revise the dat…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyTime FactorsInformation Storage and RetrievalGermanUser-Computer InterfaceSoftware DesignGermanyTerminology as TopicmedicineHumansMulticenter Studies as TopicRegistriesQuality Indicators Health CareAortic dissectionInternetPerioperative managementAcute aortic dissectionsbusiness.industryEndovascular ProceduresVascular surgerymedicine.diseaseAortic surgerylanguage.human_languageSurgeryAortic AneurysmAortic DissectionOutcome and Process Assessment Health CareTreatment OutcomeAustriaAcute DiseaselanguageSoftware designSurgeryMedical emergencyCardiology and Cardiovascular MedicinebusinessVascular Surgical ProceduresSwitzerlandThe Thoracic and cardiovascular surgeon
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The effect of tiotropium/olodaterol versus fluticasone propionate/salmeterol on left ventricular filling and lung hyperinflation in patients with COPD

2020

This exploratory, randomised, double-blind, double-dummy, multicentre, cross-over study explored the effect of 6 weeks of treatment with tiotropium/olodaterol (T/O) versus fluticasone propionate/salmeterol (F/S) on left ventricular filling in patients with chronic obstructive pulmonary disease with functional residual capacity (FRC) >120% predicted and postbronchodilator improvement of FRC ≥7.5%. Overall, 76 patients were randomised across nine sites. Treatment with T/O or F/S increased left ventricular end-diastolic volume index from baseline (adjusted mean change: T/O: 2.317 mL/m2, F/S: 2.855 mL/m2), with no statistically significant difference between treatments. However, T/O resulted…

Pulmonary and Respiratory Medicinemedicine.medical_specialtylcsh:MedicineFluticasone propionatePulmonary Disease Chronic Obstructive03 medical and health scienceschemistry.chemical_compound0302 clinical medicineFunctional residual capacityInternal medicinemedicineHumansMulticenter Studies as TopicPlethysmographIn patient1506030212 general & internal medicineTiotropium BromideLunginhaler devicesRandomized Controlled Trials as Topiclcsh:RC705-779COPDCross-Over Studiesbusiness.industrylcsh:ROlodaterollcsh:Diseases of the respiratory systemrespiratory systemmedicine.diseaseFluticasone-Salmeterol Drug CombinationBenzoxazinesBronchodilator Agentsrespiratory tract diseasesrespiratory measurement030228 respiratory systemchemistryPerspectiveCardiologyCOPD pharmacologySalmeterolVentricular fillingbusinessmedicine.drugBMJ Open Respiratory Research
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Quality of life in women undergoing urinary diversion for bladder cancer: results of a multicenter study among long-term disease-free survivors

2012

Purpose: Women undergoing radical cystectomy (RC) and urinary diversion for bladder cancer experience substantial limitations in health-related quality of life (HRQOL). However, the level of discomfort caused by different urinary diversion has been never evaluated in long term survivors. The aim of this multicenter study is to evaluate differences in HRQOL among recurrence-free women undergoing cutaneous ureterostomy (CUS), Bricker's ileal conduit (BK-IC) and Orthotopic neobladder VIP (ONB-VIP) in disease-free females treated with radical cystectomy (RC), with long-term follow up (mean 60.1 months; range 36-122 months). Materials and methods: All consecutively treated female patients from t…

Quality of lifemedicine.medical_specialtyTime FactorsTime Factormedicine.medical_treatmentUrologyDisease freeUrinary DiversionCystectomyUreterostomyCystectomyQuality of lifeSurveys and QuestionnairesInternal medicinemedicineHumansSurveys and QuestionnaireSurvivorsOrthotopic urinary reservoirUreterostomyAgedAged 80 and overBladder cancerbusiness.industryResearchBladder cancerUrinary Reservoirs ContinentUrinary diversionPublic Health Environmental and Occupational HealthCancerOrthotopic urinary reservoirsGeneral MedicineMiddle Agedmedicine.diseasehumanitiesUrinary Bladder Neoplasmsradical cystectomy; Quality of lifeMulticenter studyBladder cancer; Orthotopic urinary reservoirs; Quality of life; Urinary diversionUrinary Bladder NeoplasmFemaleSurvivorbusinessUrinary diversion; Orthotopic urinary reservoirs; Bladder cancer; Quality of lifeHumanHealth and Quality of Life Outcomes
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A survey on features of allergic rhinitis in children

2013

Objective: A number of epidemiologic studies evaluated the prevalence of allergic rhinitis (AR), but few data are available on its different clinical presentations. We addressed this survey to assess the features of AR in children and adolescents. Methods: Thirty-five centers in Italy included 2623 pediatric patients with rhinitis, of whom 2319 suffered from AR, while 304 had other kinds of rhinitis. For each patient a standardized questionnaire was filled in, including ARIA classification, the duration of symptoms, the allergen identified as clinically relevant, the co-morbidities, the kind of treatment, the response to treatment, the satisfaction with the treatment, and the feasibility of…

QuestionnairesMalePediatricsmedicine.disease_causeAdrenal Cortex HormoneAllergic rhinitisDrug treatmentAllergenAdrenal Cortex HormonesGrass pollenSurveys and QuestionnairesChildRhinitisAllergen immunotherapybiologyMedicine (all)PyroglyphidaeGeneral MedicineDust mitesResponse to treatmentPhenotypesPhenotypeItalyChild PreschoolFemaleAdolescent; Adrenal Cortex Hormones; Animals; Child; Child Preschool; Female; Histamine Antagonists; Humans; Italy; Male; Rhinitis Allergic Seasonal; Pyroglyphidae; QuestionnairesHistamine AntagonistHumanallergen immunotherapy; phenotypes; aria classification; allergic rhinitis; drug treatmentmedicine.medical_specialtyAllergen immunotherapyAdolescentHistamine AntagonistsAnimals; Questionnaires; Humans; Pyroglyphidae; Child; Italy; Adrenal Cortex Hormones; Child Preschool; Histamine Antagonists; Rhinitis Allergic Seasonal; Adolescent; Female; MaleAllergen immunotherapy; Allergic rhinitis; ARIA classification; Drug treatment; PhenotypesAllergicmedicineAllergic rhinitiAnimalsHumansPreschoolSettore MED/38 - Pediatria Generale e SpecialisticaSeasonalbusiness.industryAnimalQuestionnairePyroglyphidaeRhinitis Allergic Seasonalbiology.organism_classificationDermatologyClinical trialMulticenter studyARIA classificationbusiness
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Knowledge, opinions and attitudes of Italian mothers towards HPV vaccination and Pap test

2015

Aim This study evaluated the knowledge and attitudes of Italian mothers – whose daughters had been vaccinated in 2012 – towards primary (anti-HPV vaccination) and secondary (Pap test screening) cervical cancer prevention, as well as sources of information and mother-daughter communication on health issues. Methods The survey – part of a multicenter study carried out in 4 Italian cities (Ferrara, Rome, Cassino and Palermo) – was conducted through self-administered questionnaires. The first univariate analysis evaluated differences between mothers of under-18s and over-18s relative to knowledge and attitudes on HPV vaccination and Pap test. The second univariate analysis evaluated differences…

QuestionnairesUterine Cervical NeoplasmHealth Knowledge Attitudes PracticeCancer ResearchUterine Cervical NeoplasmsSurveys and QuestionnairesSurveys and QuestionnaireChildPapillomavirus VaccineCervical cancerUnivariate analysisPracticeMothermedicine.diagnostic_testHealth KnowledgeMedicine (all)VaccinationHpv vaccinationGeneral MedicineMiddle AgedVaccinationPap-testItalyOncologyFemaleHumanPapanicolaou TestAdultmedicine.medical_specialtyHuman papillomavirusAdolescentPublic health interventionsSocio-culturaleMothersJudgmentmedicineSexually transmitted infectionsHumansPap testPapillomavirus VaccinesAdolescent; Adult; Child; Female; Humans; Italy; Judgment; Middle Aged; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Self Report; Surveys and Questionnaires; Uterine Cervical Neoplasms; Health Knowledge Attitudes Practice; VaccinationPapillomavirus InfectionSettore MED/42 - IGIENE GENERALE E APPLICATAGynecologySexually transmitted infectionbusiness.industryhuman papillomavirus; mothers; pap-test; sexually transmitted infections; vaccinationPapillomavirus InfectionsHuman papillomavirus; Mothers; Pap-test; Sexually transmitted infections; Vaccination; Adolescent; Adult; Child; Female; Humans; Italy; Judgment; Middle Aged; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Questionnaires; Self Report; Uterine Cervical Neoplasms; Health Knowledge Attitudes Practice; Vaccination; Cancer Research; Oncology; Medicine (all)medicine.diseaseHuman papillomavirus; Mothers; Pap-test; Sexually transmitted infections; Vaccination; Adolescent; Adult; Child; Female; Humans; Italy; Judgment; Middle Aged; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Self Report; Surveys and Questionnaires; Uterine Cervical Neoplasms; Health Knowledge Attitudes Practice; Vaccination; Cancer Research; Oncology; Medicine (all)Sexual intercourseHuman papillomaviruMulticenter studyFamily medicineAttitudesSelf Reportbusiness
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Rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART): study protocol for a randomized controlled trial.

2012

Abstract Background Acute respiratory distress syndrome (ARDS) is associated with high in-hospital mortality. Alveolar recruitment followed by ventilation at optimal titrated PEEP may reduce ventilator-induced lung injury and improve oxygenation in patients with ARDS, but the effects on mortality and other clinical outcomes remain unknown. This article reports the rationale, study design, and analysis plan of the Alveolar Recruitment for ARDS Trial (ART). Methods/Design ART is a pragmatic, multicenter, randomized (concealed), controlled trial, which aims to determine if maximum stepwise alveolar recruitment associated with PEEP titration is able to increase 28-day survival in patients with …

Research designARDSmedicine.medical_specialtyTime FactorsVentilator-Induced Lung InjuryAlveolar recruitmentTreatment outcomeRandomizedMedicine (miscellaneous)Settore MED/41 - AnestesiologiaHospital mortalitylaw.inventionPositive-Pressure RespirationStudy ProtocolMechanical ventilationClinical trialsRandomized controlled trialClinical ProtocolslawMedicineHumansPharmacology (medical)Hospital MortalityPEEPProtocol (science)Respiratory Distress SyndromeAcute respiratory distress syndromebusiness.industryrespiratory systemLength of Staymedicine.diseaseClinical trialPulmonary AlveoliARDS; Alveolar recruitment; PEEPIntensive Care UnitsTreatment OutcomeMulticenter studyBarotraumaResearch DesignPhysical therapyARDSbusinessBrazilTrials
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Rivaroxaban in Peripheral Artery Disease after Revascularization

2020

Abstract Background Patients with peripheral artery disease who have undergone lower-extremity revascularization are at high risk for major adverse limb and cardiovascular events. The efficacy and ...

RivaroxabanAspirinmedicine.medical_specialtyArterial diseasebusiness.industrymedicine.medical_treatmentGeneral MedicineDisease030204 cardiovascular system & hematologyRevascularizationlaw.invention03 medical and health sciences0302 clinical medicinePharmacotherapyRandomized controlled trialMulticenter studylawInternal medicineCardiologyMedicine030212 general & internal medicinebusinessmedicine.drugNew England Journal of Medicine
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