Search results for "Multidisciplinary"

2013

Following traumatic brain injury (TBI) neuroinflammatory processes promote neuronal cell loss. Alpha-melanocyte-stimulating hormone (α-MSH) is a neuropeptide with immunomodulatory properties, which may offer neuroprotection. Due to short half-life and pigmentary side-effects of α-MSH, the C-terminal tripeptide α-MSH(11–13) may be an anti-inflammatory alternative. The present study investigated the mRNA concentrations of the precursor hormone proopiomelanocortin (POMC) and of melanocortin receptors 1 and 4 (MC1R/MC4R) in naive mice and 15 min, 6, 12, 24, and 48 h after controlled cortical impact (CCI). Regulation of POMC and MC4R expression did not change after trauma, while MC1R levels incr…

Acute selective ablation of rat insulin promoter-expressing (RIP HER ) neurons defines their orexigenic nature

2012

Rat insulin promoter (RIP)-expressing neurons in the hypothalamus control body weight and energy homeostasis. However, genetic approaches to study the role of these neurons have been limited by the fact that RIP expression is predominantly found in pancreatic β-cells, which impedes selective targeting of neurons. To define the function of hypothalamic RIP-expressing neurons, we set out to acutely and selectively eliminate them via diphtheria toxin-mediated ablation. Therefore, the diphtheria toxin receptor transgene was specifically expressed upon RIP-specific Cre recombination using a RIP-Cre line first described by Herrera (RIP HER -Cre) [Herrera PL (2000) Development 127:2317–2322]. Usi…

Single-Center Retrospective Series of Intracranial Aneurysms Treated with the Barricade Coil System: Immediate and Six-Month Results

2020

Abstract Intracranial aneurysms (IAs) are most commonly found at the branch points of large arteries that form the circle of Willis. The prevalence of IAs in the adult population is 1–5%. IAs rupture is associated with subarachnoid haemorrhage (SAH) in 6–8 cases per 100 000 population, causing mortality in 40–50%. Aneurysm treatment is used to prevent rupture or rebleeding (for ruptured IAs). Randomised trials demonstrated the superiority of endovascular treatment (EVT) of ruptured aneurysms with coil systems over surgery. The objective of the study was to evaluate the effectiveness of the Barricade coil system in the treatment of intracranial aneurysms. Detachable platinum coils, since the…

. New ground-based lidar enables volcanic CO2 flux measurements

2015

AbstractThere have been substantial advances in the ability to monitor the activity of hazardous volcanoes in recent decades. However, obtaining early warning of eruptions remains challenging, because the patterns and consequences of volcanic unrests are both complex and nonlinear. Measuring volcanic gases has long been a key aspect of volcano monitoring since these mobile fluids should reach the surface long before the magma. There has been considerable progress in methods for remote and in-situ gas sensing, but measuring the flux of volcanic CO2—the most reliable gas precursor to an eruption—has remained a challenge. Here we report on the first direct quantitative measurements of the volc…

Urban Services to Ecosystems: An Introduction

2021

Green infrastructure is a structural system of naturally developed human societies, capable of preserving and ensuring as much space as possible to the local biodiversity. For this reason, green infrastructure shall be planned and designed so that the urban built environment is in harmony with the surrounding biotic communities. The challenge is to sustain nature-based solutions in order to improve citizens’ awareness towards natural and semi-natural ecosystems while providing our society with a more liveable, healthier, safer and fairer environment. This book puts an emphasis on the services the city can offer to nature, thanks to a multidisciplinary approach involving scientists and pract…

Optimisation of Conditions for Extraction of Biologically Active Compounds from Common Bryophytes in Latvia / Latvijâ Augoðu Briofîtu Ekstrakcijas Ap…

2015

Abstract Bryophytes are the second largest taxonomic group in the plant kingdom. They contain a high number of biologically active compounds. Studies of their composition are important for understanding evolutionary processes in the plant kingdom. The aim of this study was to assess bryophyte secondary metabolite extraction options and to increase the yields of polyphenols and substances determining the free radical scavenging activity of bryophyte extracts. Similar studies have been conducted using higher plants as model organisms, but not using bryophytes. Comparison of five extraction methods (conventional, Soxhlet extraction, treatment with microwaves, ultrasound, and supercritical CO2 …

Importance of music for and in the training of the physiotherapist

2021

espanolResumen Introduccion: son muchos los especialistas de Ciencias de la Salud que han demostrado lo interesante y significativo de utilizar la Musica en sus tratamientos terapeuticos. No obstante, en Espana, solo una universidad publica cuenta con formacion musical para capacitarlos en su utilizacion. Objetivo: esta investigacion intento demostrar la necesidad de formacion musical desde el Grado de Fisioterapia, a traves de propuestas de Movimiento con Musica desde la perspectiva dalcroziana. Materiales y metodos: se realizaron una serie de practicas de concienciacion corporal con Musica, atendiendo al trabajo de distintos elementos musicales y partiendo de las propuestas de Jaques-Dalc…

Modular Small Diameter Vascular Grafts with Bioactive Functionalities.

2015

We report the fabrication of a novel type of artificial small diameter blood vessels, termed biomimetic tissue-engineered blood vessels (bTEBV), with a modular composition. They are composed of a hydrogel scaffold consisting of two negatively charged natural polymers, alginate and a modified chitosan, N,O-carboxymethyl chitosan (N,O-CMC). Into this biologically inert scaffold two biofunctionally active biopolymers are embedded, inorganic polyphosphate (polyP) and silica, as well as gelatin which exposes the cell recognition signal, Arg-Gly-Asp (RGD). These materials can be hardened by exposure to Ca(2+) through formation of Ca(2+) bridges between the polyanions, alginate, N,O-CMC, and polyP…

Landscape Ecological Structure in the Eastern Part of the North Vidzeme Biosphere Reserve, Latvia

2008

Landscape Ecological Structure in the Eastern Part of the North Vidzeme Biosphere Reserve, Latvia Latvia is a country where the forest area has increased and habitat fragmentation has reversed compared with many other European countries. In order to examine the effect of this expansion on biodiversity, vegetation maps dating from 2002 and the years 1930-1936 were used for comparative landscape structure analyses while archive materials from forest plans, and data from the national forest management database were used for land use analysis. Four landscape ecoregions in the eastern side of the North Vidzeme Biosphere Reserve were selected for analysis. Landscape structure indicators derived f…

Biotic and abiotic soil properties influence survival of Listeria monocytogenes in soil

2013

International audience; Listeria monocytogenes is a food-borne pathogen responsible for the potentially fatal disease listeriosis and terrestrial ecosystems have been hypothesized to be its natural reservoir. Therefore, identifying the key edaphic factors that influence its survival in soil is critical. We measured the survival of L. monocytogenes in a set of 100 soil samples belonging to the French Soil Quality Monitoring Network. This soil collection is meant to be representative of the pedology and land use of the whole French territory. The population of L. monocytogenes in inoculated microcosms was enumerated by plate count after 7, 14 and 84 days of incubation. Analysis of survival pr…