Search results for "Multiple Organ Failure"

showing 3 items of 13 documents

Pathology of Rotavirus-driven Multiple Organ Failure in a 16-month-old Boy

2019

International audience; Autopsy investigation of a fatal case of rotavirus severe acute gastroenteritis and multiple organ failure in a 16-month boy with previous intrauterine growth retardation showed colocalization of nonstructural and structural rotavirus proteins within viroplasms in nephrons. This case brings new insights into extraintestinal rotavirus infection and new clues to its abilities to bind to human histo-blood group antigens.

Microbiology (medical)MaleRotavirusFatal outcomeMultiple Organ FailureAutopsymedicine.disease_causeRotavirus Infections03 medical and health sciences0302 clinical medicineFatal OutcomeAntigen[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases030225 pediatricsRotavirusmedicineHumans030212 general & internal medicineHuman histo-blood group antigens[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/PediatricsFetal Growth RetardationGrowth retardationbusiness.industryRotavirus severe acute gastroenteritisInfantvirus diseases[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and GastroenterologyNephronsAcute gastroenteritisAcute Kidney InjuryShock Septic3. Good healthGastroenteritisRotavirus infectionInfectious DiseasesPediatrics Perinatology and Child HealthImmunologyAutopsybusiness[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Single Preoperative Oral Application of Ascorbic Acid Does Not Affect Postoperative Plasma Levels of Ascorbic Acid

2002

<i>Background and Aims:</i> A decrease in ascorbic acid (AA) plasma concentration is well known during the postoperative period and postulated to be caused by increased radical scavenging activity in response to surgical trauma. This often affects postoperative patients and is associated with multiple organ failure. Therefore, substitution of AA could potentially decrease the risk of postoperative complications. This study examines the effect of preoperative oral administration of 1,000 mg AA on the postoperative AA plasma concentration. <i>Methods:</i> 54 patients were randomly split into two groups; patients in group 1 received no AA preoperatively while group 2 re…

medicine.medical_specialtyRandomizationAntioxidantMultiple Organ Failuremedicine.medical_treatmentAdministration OralMedicine (miscellaneous)Ascorbic AcidGastroenterologyAntioxidantsPostoperative ComplicationsOral administrationInternal medicinePreoperative CareBlood plasmamedicineHumansOral applicationPostoperative PeriodAgedNutrition and DieteticsVitamin CChemistryPlasma levelsMiddle AgedAscorbic acidSurgical Procedures OperativeAnesthesiaAnnals of Nutrition and Metabolism
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The role of the microcirculation in multiple organ dysfunction syndrome (MODS): a review and perspective

1996

Major advances in intensive care medicine during the past two decades have altered the spectrum of disease encountered by intensive care physicians, anaesthesiologists, traumatologists and pathologists. One of the most important manifestations of severe trauma or infections is the multiple organ dysfunction syndrome (MODS), a life-threatening condition that often ends in multiple organ failure (MOF) and death. Evidence gathered from clinical and morphological observations in humans, taken together with experimental animal studies and a vast accumulation of in vitro data, clearly indicate that the microcirculation lies at the centre of this complex process, which results in peripheral vascul…

medicine.medical_specialtybusiness.industryMicrocirculationMultiple Organ FailureOrgan dysfunctionCell BiologyGeneral MedicineDiseasemedicine.diseasePathology and Forensic MedicineMicrocirculationSepsisExperimental animalSevere traumaIntensive careAnimalsHumansMedicinemedicine.symptombusinessMultiple organ dysfunction syndromeIntensive care medicineMolecular BiologyVirchows Archiv
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