Pathology of Rotavirus-driven Multiple Organ Failure in a 16-month-old Boy

6533b86efe1ef96bd12cc08f

RESEARCH PRODUCT

Pathology of Rotavirus-driven Multiple Organ Failure in a 16-month-old Boy

Patrick Callier Georges Tarris Alexis De Rougemont Frédéric Huet Laurent Martin Gaël Belliot

subject

Microbiology (medical)Male Rotavirus Fatal outcome Multiple Organ Failure Autopsy medicine.disease_cause Rotavirus Infections 03 medical and health sciences 0302 clinical medicine Fatal Outcome Antigen [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases 030225 pediatrics Rotavirus medicine Humans 030212 general & internal medicine Human histo-blood group antigens [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics Fetal Growth Retardation Growth retardation business.industry Rotavirus severe acute gastroenteritis Infant virus diseases [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology Nephrons Acute gastroenteritis Acute Kidney Injury Shock Septic 3. Good health Gastroenteritis Rotavirus infection Infectious Diseases Pediatrics Perinatology and Child Health Immunology Autopsy business [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition

description

International audience; Autopsy investigation of a fatal case of rotavirus severe acute gastroenteritis and multiple organ failure in a 16-month boy with previous intrauterine growth retardation showed colocalization of nonstructural and structural rotavirus proteins within viroplasms in nephrons. This case brings new insights into extraintestinal rotavirus infection and new clues to its abilities to bind to human histo-blood group antigens.

year	journal	country	edition	language
2019-12-01

10.1097/inf.0000000000002472 https://hal-univ-bourgogne.archives-ouvertes.fr/hal-02380000

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