Search results for "Multiple"
showing 10 items of 2678 documents
Sequentially Rejective Test Procedures for Detecting Outlying Cells in One- and Two-Sample Multinomial Experiments
1985
For multiple testing of multinomial models in the case of one or two samples we propose using test procedures based on the principle described by MARCUS, PERITZ and GABRIEL (1976). These methods are based in each step of the sequentially rejective strategy on tests which exhaust the full α level (i.e. which are not conservative). The tests can be performed in a finite or asymptotic version.
Bayesian models for data missing not at random in health examination surveys
2018
In epidemiological surveys, data missing not at random (MNAR) due to survey nonresponse may potentially lead to a bias in the risk factor estimates. We propose an approach based on Bayesian data augmentation and survival modelling to reduce the nonresponse bias. The approach requires additional information based on follow-up data. We present a case study of smoking prevalence using FINRISK data collected between 1972 and 2007 with a follow-up to the end of 2012 and compare it to other commonly applied missing at random (MAR) imputation approaches. A simulation experiment is carried out to study the validity of the approaches. Our approach appears to reduce the nonresponse bias substantially…
Asymptotics of correlation functions of the Heisenberg-Ising chain in the easy-axis regime
2016
We analyze the long-time large-distance asymptotics of the longitudinal correlation functions of the Heisenberg-Ising chain in the easy-axis regime. We show that in this regime the leading asymptotics of the dynamical two-point functions is entirely determined by the two-spinon contribution to their form factor expansion. Its explicit form is obtained from a saddle-point analysis of the corresponding double integral. It describes the propagation of a wave front with velocity $v_{c_1}$ which is found to be the maximal possible group velocity. Like in wave propagation in dispersive media the wave front is preceded by a precursor running ahead with velocity $v_{c_2}$. As a special case we obta…
Visualizing categorical data in ViSta
2003
The modules in the statistical package ViSta related to categorical data analysis are presented These modules are: visualization of frequency data with mosaic and bar plots, correspondence analysis, multiple correspondence analysis and loglinear analysis. All these methods are implemented in ViSta with a big emphasis on plots and graphical representations of data, as well as interactivity for the user with the system. These provide a system that has shown to be easy, useful, and powerful, both for novice and experienced users.
SeqEditor: an application for primer design and sequence analysis with or without GTF/GFF files
2021
[Motivation]: Sequence analyses oriented to investigate specific features, patterns and functions of protein and DNA/RNA sequences usually require tools based on graphic interfaces whose main characteristic is their intuitiveness and interactivity with the user’s expertise, especially when curation or primer design tasks are required. However, interface-based tools usually pose certain computational limitations when managing large sequences or complex datasets, such as genome and transcriptome assemblies. Having these requirments in mind we have developed SeqEditor an interactive software tool for nucleotide and protein sequences’ analysis.
Evaluating currency crises: the case of the European monetary system
2007
In this paper we examine the nature of currency crises. We ascertain whether the currency crises of the European Monetary System (EMS) were based either on fundamentals, or on self-fulfilling market expectations driven by extrinsic uncertainty. In particular, we extend previous work of Jeanne and Masson (J Int Econ 50:327–350, 2000) regarding the evaluation of currency crisis. We contribute to the existing literature proposing the use of Markov regime-switching with time-varying transition probability model. Our empirical results suggest that the currency crises of the EMS were not due only to market expectations driven by external uncertainty, or ‘sunspots’, but also to fundamental variabl…
STATIS and DISTATIS: optimum multitable principal component analysis and three way metric multidimensional scaling
2012
STATIS is an extension of principal component analysis PCA tailored to handle multiple data tables that measure sets of variables collected on the same observations, or, alternatively, as in a variant called dual-STATIS, multiple data tables where the same variables are measured on different sets of observations. STATIS proceeds in two steps: First it analyzes the between data table similarity structure and derives from this analysis an optimal set of weights that are used to compute a linear combination of the data tables called the compromise that best represents the information common to the different data tables; Second, the PCA of this compromise gives an optimal map of the observation…
Multiple factor analysis: principal component analysis for multitable and multiblock data sets
2013
Multiple factor analysis MFA, also called multiple factorial analysis is an extension of principal component analysis PCA tailored to handle multiple data tables that measure sets of variables coll...
CARE: context-aware sequencing read error correction.
2020
Abstract Motivation Error correction is a fundamental pre-processing step in many Next-Generation Sequencing (NGS) pipelines, in particular for de novo genome assembly. However, existing error correction methods either suffer from high false-positive rates since they break reads into independent k-mers or do not scale efficiently to large amounts of sequencing reads and complex genomes. Results We present CARE—an alignment-based scalable error correction algorithm for Illumina data using the concept of minhashing. Minhashing allows for efficient similarity search within large sequencing read collections which enables fast computation of high-quality multiple alignments. Sequencing errors ar…
Multiple Comparisons of Treatments with Stable Multivariate Tests in a Two‐Stage Adaptive Design, Including a Test for Non‐Inferiority
2000
The application of stabilized multivariate tests is demonstrated in the analysis of a two-stage adaptive clinical trial with three treatment arms. Due to the clinical problem, the multiple comparisons include tests of superiority as well as a test for non-inferiority, where non-inferiority is (because of missing absolute tolerance limits) expressed as linear contrast of the three treatments. Special emphasis is paid to the combination of the three sources of multiplicity - multiple endpoints, multiple treatments, and two stages of the adaptive design. Particularly, the adaptation after the first stage comprises a change of the a-priori order of hypotheses.