Search results for "Multiple"

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand.

2014

Abstract Ethnopharmacological relevance Thai medicine has a long tradition of tonifying medicinal plants. In the present investigation, we studied the flower extracts of Jasminum sambac, Mammea siamensis, Mesua ferrea, Michelia alba, Mimusops elengi, and Nelumbo nucifera and speculated that these plants might influence metabolism and substance flow in the body. Materials and methods Isolation of porcine brain capillary endothelial cells (PBCECs) as well as multidrug-resistance CEM/ADR5000 leukemia cells, MDA-M;B-231 breast cancer, U-251 brain tumor, and HCT-116 colon cancer cells were used. The calcein-acetoxymethylester (AM) assay was used to measure inhibition of P-glycoprotein transport.…

A symmetric Galerkin BEM for plate bending analysis

2009

Abstract The Symmetric Galerkin Boundary Element Method is employed in thin plate bending analysis in accordance with the Love–Kirchhoff kinematical assumption. The equations are obtained through the stationary conditions of the total potential energy, written for a plate whose boundary is discretized in boundary elements. Since the matrix coefficients are made up as double integrals with high order singularities, a strategy is shown to compute these coefficients in closed form. Furthermore, in order to model the kinematical discontinuities and to weight the mechanical quantities along the boundary elements, the Lagrangian quadratic shape functions, rather than C 1 type (spline, Hermitian),…

Synthetic aperture superresolution with multiple off-axis holograms

2006

An optical setup to achieve superresolution in microscopy using holographic recording is presented. The technique is based on off-axis illumination of the object and a simple optical image processing stage after the imaging system for the interferometric recording process. The superresolution effect can be obtained either in one step by combining a spatial multiplexing process and an incoherent addition of different holograms or it can be implemented sequentially. Each hologram holds the information of each different frequency bandpass of the object spectrum. We have optically implemented the approach for a low-numerical-aperture commercial microscope objective. The system is simple and rob…

Passive time-multiplexing super-resolved technique for axially moving targets

2013

In this paper we present a super-resolving approach for detecting an axially moving target that is based upon a time-multiplexing concept and that overcomes the diffraction limit set by the optics of an imaging camera by a priori knowledge of the high-resolution background in front of which the target is moving. As the movement trajectory is axial, the approach can be applied to targets that are approaching or moving away from the camera. By recording a set of low-resolution images at different target axial positions, the super-resolving algorithm weights each image by demultiplexing them using the high-resolution background image and provides a super-resolved image of the target. Theoretic…

The relationship between BAFF serum levels, anti-NMDAR autoantibodies and fatigue in patients with systemic lupus erythematosus and multiple sclerosi…

2020

A Transition Zone Complex Regulates Mammalian Ciliogenesis and Ciliary Membrane Composition

2011

Mutations in genes encoding ciliary components cause ciliopathies, but how many of these mutations disrupt ciliary function is unclear. We investigated Tectonic1 (Tctn1), a regulator of mouse Hedgehog signaling, and found that it is essential for ciliogenesis in some, but not all, tissues. Cell types that do not require Tctn1 for ciliogenesis require it to localize select membrane-associated proteins to the cilium, including Arl13b, AC3, Smoothened and Pkd2. Tctn1 forms a complex with multiple ciliopathy proteins associated with Meckel (MKS) and Joubert (JBTS) syndromes, including Mks1, Tmem216, Tmem67, Cep290, B9d1, Tctn2, and Cc2d2a. Components of the Tectonic ciliopathy complex colocaliz…

Hypoplastic amelogenesis imperfecta with multiple impacted teeth - report of two cases

2010

Amelogenesis Imperfecta (AI) represents a group of developmental conditions, genomic in origin, which affect the structure and clinical appearance of enamel of all or nearly all the teeth in a more or less equal manner. It is usually inherited either as an X-linked, autosomal dominant or autosomal recessive trait. The enamel may be hypoplastic, hypomineralised or both and affected teeth may be discolored, sensitive or prone to disintegration. Diagnosis is based on the family history, pedigree plotting and meticulous clinical observation. The treatment of patients with AI should start with early diagnosis and intervention to prevent latter restorative problems. Herein, we present two case re…

Exploiting programmable architectures for WiFi/ZigBee inter-technology cooperation

2014

The increasing complexity of wireless standards has shown that protocols cannot be designed once for all possible deployments, especially when unpredictable and mutating interference situations are present due to the coexistence of heterogeneous technologies. As such, flexibility and (re)programmability of wireless devices is crucial in the emerging scenarios of technology proliferation and unpredictable interference conditions. In this paper, we focus on the possibility to improve coexistence performance of WiFi and ZigBee networks by exploiting novel programmable architectures of wireless devices able to support run-time modifications of medium access operations. Differently from software…

Acorn Ants May Create and Use Two Entrances to the Nest Cavity

2021

Many ant species construct large nests that are inhabited by numerous workers, but other species dwell in ready-for-use cavities and live in small colonies. Ants of the genus Temnothorax inhabit small cavities, e.g., in acorns, twigs, and under rocks. Although a preference for nest sites with a narrower entrance is known, recent studies have shown that they also use cavities with wider entrances and may modify the size of such entrances. As good cavities for nest sites are a limited resource, the possibility to modify a potential nest site, including a reduction in the size of the hole, should be a favorable matter for the ants. Through field and laboratory experiments, I studied the acorn …

The influence of climate change on the soil organic carbon content in Italy from 1961 to 2008

2011

Abstract Soils are the biggest carbon store in the world (1500 Gt, e.g. 1.5 × 10 21  g). The European Commission indicates the accounting of soil organic carbon (SOC) variations in space and time as the first step in the strategy for soil protection. It is indeed necessary in evaluating the risk of soil organic matter decline and soil biodiversity decline, and when evaluating the role played by soils in global CO 2 accounting. Previous maps of SOC variations in Italy did not consider the direct effect of climate. There is a marked inter-dependence between SOC and climate. SOC increases with the increase in precipitations and decreases with a rise in temperatures. It is also known that land …